DRSC/TRiP Functional Genomics Resources

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Protein Alignment drpr and CSF1R

DIOPT Version :9

Sequence 1:NP_001261276.1 Gene:drpr / 38218 FlyBaseID:FBgn0027594 Length:1042 Species:Drosophila melanogaster
Sequence 2:NP_001275634.1 Gene:CSF1R / 1436 HGNCID:2433 Length:972 Species:Homo sapiens


Alignment Length:69 Identity:20/69 - (28%)
Similarity:25/69 - (36%) Gaps:28/69 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly   383 GWSSAQCTRPCTF---LRYGPNCELTCNCKNGAKCSPVNGTCLC-APGWRGPT------------ 431
            ||      |..||   |||.|...:.....||      :||.|| |.|:..|.            
Human   388 GW------RALTFELTLRYPPEVSVIWTFING------SGTLLCAASGYPQPNVTWLQCSGHTDR 440

  Fly   432 CEES 435
            |:|:
Human   441 CDEA 444

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
drprNP_001261276.1 EMI 27..92 CDD:284877
EGF_CA 274..319 CDD:304395
DSL <479..518 CDD:302925
DSL <567..606 CDD:302925
CSF1RNP_001275634.1 IG_like 28..85 CDD:214653
ig 207..293 CDD:365836
Ig4_SCFR_like 299..400 CDD:319281 6/17 (35%)
Ig 416..495 CDD:319273 8/29 (28%)
Regulatory juxtamembrane domain 542..574
PTKc_CSF-1R 543..914 CDD:133237
Activation loop 796..818
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 918..950
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0200
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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