Protein Alignment drpr and drpr

DIOPT Version :10

• Sequence 1: NP_001261276.1
• Gene: drpr / 38218
• FlyBaseID: FBgn0027594
• Length: 1042
• Species: Drosophila melanogaster
• Sequence 2: XP_061519707.1
• Gene: drpr / 1269892
• VectorBaseID: AGAMI1_015089
• Length: 1181
• Species: Anopheles gambiae
• Alignment Length: 1126
• Identity: 517/1126 - (45%)
• Similarity: 668/1126 - (59%)
• Gaps: 116/1126 - (10%)

  Fly     1 MLPVILIACLAQLVLAQADL-KD--LDGPNICKRRELYNVDVVYTELQSFQERGSTWCVTFPPRC 62
            :|.::|..|....|||..:| ||  |:|||:||..|...|.:.....:::|||...||:..||||
Mosquito    23 LLAMLLAICHDVRVLAHTELIKDDHLEGPNVCKEVENITVTITTPREEAYQERYQKWCLGIPPRC 87

  Fly    63 STYRIKHRVVNKTKTIAKNRIVRDCCDGYIASAGE--CVPHCSEPCQHGRCISPEKCKCDHGYGG 125
            |.||||.|.||:|:|:...|||:.||.||.....:  |:|.|...|.:|.||:|:.|:|:.||.|
Mosquito    88 SAYRIKIRTVNETRTVINQRIVKKCCVGYQLDEEQLHCIPECKAGCVYGTCINPDVCRCNKGYAG 152

  Fly   126 PACDINCPPGWYGRNCSMQCDCLNNAVCEPFSGDCECAKGYTGARCADICPEGFFGANCSEKCRC 190
            ..|:|:|||..:|.:|...|.|.|.|||....|.|||::|:.|..|.:.||...||.:|:|.|:|
Mosquito   153 KTCNISCPPNVWGSDCKQPCKCANGAVCNAADGSCECSRGFKGRYCEETCPSDRFGQDCAEICQC 217

  Fly   191 ENGGKCHHVSGECQCAPGFTGPLCDMRCPDGKHGAQCQQDCPCQNDGKCQPETGACMCNPGWTGD 255
            :|||||.||||||.||.|:|||||...||.|.||||||..|.|||.|.|.|.||.|:|..|:||.
Mosquito   218 KNGGKCDHVSGECFCAAGYTGPLCTEPCPAGTHGAQCQSKCRCQNGGTCDPVTGECVCPAGFTGM 282

  Fly   256 VCANKCPVGSYGPGCQESCECYKGAPCHHITGQCECPPGYRGERCFDECQLNTYGFNCSMTCDCA 320
            ||||:|..|.||..|.:.|||:.||.|..:||||.|.||:.|.:|.|.|..|.||.||:.||.|.
Mosquito   283 VCANRCQPGWYGLQCAKRCECFNGADCDRVTGQCICAPGFMGAKCLDSCPNNQYGINCTETCRCQ 347

  Fly   321 NDAMCDRANGTCICNPGWTGAKCAERICEANKYGLDCNRTCECDMEHTDLCHPETGNCQCSIGWS 385
            |:.:||.|:|.|.|..||.||.|.:|||...:||.:|...|:|..::|.:|||.||.|.|..|||
Mosquito   348 NEGICDTADGRCTCPDGWKGADCGQRICPQGRYGANCTGVCDCKWDNTKMCHPWTGKCLCEPGWS 412

  Fly   386 SAQCTRPCTFLRYGPNCELTCNCKNGAKCSPVNGTCLCAPGWRGPTCEESCEPGTFGQDCALRCD 450
            ::.|.|||.|||||.:|:|.|||||.:.||.::|||||..|::|.:|||.|...|:||:|:.||.
Mosquito   413 NSACDRPCRFLRYGQDCQLMCNCKNSSPCSHIDGTCLCIAGFKGESCEEPCSNNTYGQNCSERCQ 477

  Fly   451 CQNGAKCEPETGQCLCTAGWKNIKCDRPCDLNHFGQDCAKVCDCHNNAACNPQNGSCTCAAGWTG 515
            |.|||.|:.|:|:|.|..||:.||||||||..|:|:||.:.|.|.|...|||.||.|||.|||||
Mosquito   478 CMNGAACDGESGKCACAPGWQGIKCDRPCDAQHYGRDCTEKCHCQNGGVCNPINGQCTCPAGWTG 542

  Fly   516 ERCERKCDTGKFGHDCAQKCQCDFNNSLACDATNGRCVCKQDWGGVHCETNCRSGYYGENCDKVC 580
            |.|::||..|:||.:|.|.|.|...|||||:||.|||:||.|||||.||:.|..|||||:|.::|
Mosquito   543 ELCDKKCSPGRFGQNCEQLCDCHLENSLACNATTGRCICKADWGGVRCESRCPLGYYGESCSEIC 607

  Fly   581 RCLNNSSCDPDSGNCICSAGWTGADCAEPCPPGFYGMECKERCPEILHGNKSCDHITGEILCRTG 645
            .|.|||||||.:|.||||.||||..|.||||.||:|..|.|||......|::|:.|||:..|..|
Mosquito   608 TCHNNSSCDPTTGECICSRGWTGPSCNEPCPKGFFGHGCMERCSGSAESNRTCNPITGQYSCPPG 672

  Fly   646 YIGLTCEHPCPAGLYGPGCKLKC-NCEHGGECNHVTGQCQCLPGWTGSNCNESCPTDTYGQGCAQ 709
            |:|.||||||.:|.||..|:.|| .|.:|.||:|:||:|||.|||.|..|...|....||..|:|
Mosquito   673 YVGPTCEHPCSSGYYGQDCQKKCPECRNGAECSHITGECQCTPGWKGPLCETVCEGMYYGTNCSQ 737

  Fly   710 RCRCVHHKVCRKADGMCICETGWSGTRCDEVCPEGFYGEHCMNTCACPSANFQCHAAHGCVCRSG 774
            .|.|.::..|||.||.|||:.||.|.||||||||||||.|||..|.||:.||.||||.||||..|
Mosquito   738 VCNCKNNAKCRKNDGTCICDAGWMGHRCDEVCPEGFYGNHCMEACECPAGNFLCHAAKGCVCSVG 802

  Fly   775 YTGDNCDELIASQRIADQSENSSRASVALTLVLMTLFACIIFAVFIYYRRRVSNLKTEIAHV--H 837
            :||.||||.:.:....|:.:..|.:|....:||:.:|..::.|:.:||||||::||.|:.||  :
Mosquito   803 WTGKNCDERMTNMLTQDRVDEGSSSSTVWMVVLLLMFGAMLTAMLLYYRRRVASLKAEVNHVVNY 867

  Fly   838 YTHDTNPPSWPPNHNFDNPVYG---------------------------MQAETRL----LPNNM 871
            .|.:      .|:| ||||||.                           :.|.|.|    ||||:
Mosquito   868 MTQE------QPSH-FDNPVYARTGGGGAPNGGSIASGTLSSNGTIVPPLDARTGLLRNVLPNNL 925

  Fly   872 RSKMN-----NFDQRSTMSTDYGDDCNASGRVGSYSINYNHDLLTKNLNADRTNPIVYNESLKEE 931
            |..|:     |.|:.|....:|..|       .|.|.::......||..||.|||..      ::
Mosquito   926 RDVMSGRRKQNQDKYSYPDNEYDVD-------KSLSFSHYRPESLKNFEADMTNPNF------KD 977

  Fly   932 HVYDEIKHKEGY----KDP--VKIYSKILFPEDEYDHLDYSRPSTSQKPHYHRMNDA-------- 982
            ||||||:.|:..    :||  ..||:       ||||||||||.:|.|.||.||||.
Mosquito   978 HVYDEIRLKDSIAALSRDPNYAYIYT-------EYDHLDYSRPGSSHKAHYFRMNDGASNGNVTA 1035

  Fly   983 ----------------------MLNINQDEEKPSNVKNMTV-----LLNKPLP--PTEPEPQHEC 1018
                                  .:|:.:|......:.|::.     .:|..||  |:.| .:.:|
Mosquito  1036 NGGGTLTGSIASSNAYGNGSPKAINVLRDTASAGPINNLSAPPTASRVNNLLPAIPSVP-AEAKC 1099

  Fly  1019 FDNTNTNLDN-VSTASPSSSP 1038
            .:..:.:|.| :|::|.||||
Mosquito  1100 SNTDSASLGNDLSSSSNSSSP 1120

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drpr	NP_001261276.1	EMI	26..92	CDD:462204	31/65 (48%)
		EGF_CA	274..319	CDD:473889	24/44 (55%)
		gliding_CglD	<451..579	CDD:468178	76/127 (60%)
		DSL	567..609	CDD:473190	26/41 (63%)
drpr	XP_061519707.1	None