Protein Alignment drpr and pear1

DIOPT Version :10

• Sequence 1: NP_001261276.1
• Gene: drpr / 38218
• FlyBaseID: FBgn0027594
• Length: 1042
• Species: Drosophila melanogaster
• Sequence 2: XP_017952446.2
• Gene: pear1 / 100489801
• XenbaseID: XB-GENE-6045593
• Length: 1087
• Species: Xenopus tropicalis
• Alignment Length: 1104
• Identity: 361/1104 - (32%)
• Similarity: 516/1104 - (46%)
• Gaps: 135/1104 - (12%)

  Fly     1 MLPVILIACLAQLVLAQADLKDLDGPNICKRRELYNVDVVYTELQSFQERG-----STWCVTFPP 60
            |:|::.:  |.|:...:: |...| ||:|...|.:.:.|..:..|.:.:..     |:|  .:..
 Frog     7 MIPIVWM--LVQIQFGKS-LSPND-PNVCSFWESFTLAVKESYTQPYSQLSPDSCDSSW--NYFK 65

  Fly    61 RCSTYRIKHRVVNKTKTIAKNRIVRD------CCDGYIASAGECVPHCSEPCQHGRCISPEKCKC 119
            .|:..:|.:|      |..::|:..|      ||.||..|...|||.|::.|.|||||:|::|:|
 Frog    66 ACTPQKILYR------TAYRHRVKLDYRRRYWCCKGYYESNDICVPRCTQECVHGRCIAPDQCQC 124

  Fly   120 DHGYGGPACDINCPPGWYGRNCSMQCDCLNNAVCEPFSGDCECAKGYTGARCADICPEGFFGANC 184
            :.|:.|..|...|....:|..|:..|.|.||..|:..||.|.|..|:....|...|..|.:|..|
 Frog   125 EPGWRGKDCSSACEAHVWGPKCNSTCPCQNNGACDAASGTCICPPGFRDPFCEKPCDPGTYGGGC 189

  Fly   185 SEKCRCENGGKCHHVSGECQCAPGFTGPLCDMRCPDGK-HGAQCQQDCPCQNDGKCQPETGACMC 248
            |..|:|:||.:|...:|.|.|..|:|||.|::||.:.: ....|...|.||:.|.|...:|.|.|
 Frog   190 SLSCQCKNGAECDPENGACLCPEGYTGPYCEIRCKEVQPANFSCSDQCLCQSGGICNQSSGECSC 254

  Fly   249 NPGWTGDVCANKCPVGSYGPGCQESCECYKGAPCHHITGQCECPPGYRGERCFDECQLNTYGFNC 313
            .|||.|.:|:..||.|.||..|::.|.|:.|..|...||||.|..||.|:.|.:||.:..||.:|
 Frog   255 PPGWMGSLCSIPCPDGYYGRNCKQECLCHNGGQCDPKTGQCLCSEGYTGDHCREECPIGKYGKDC 319

  Fly   314 SMTCDCANDAMCDRANGTCICNPGWTGAKCAERICEANKYGLDCNRTCECDMEHTDLCHPETGNC 378
            |..|||.|...|...||.|:|..|:.|..|.||:|....||:.||..|.||..|:..|||.:|.|
 Frog   320 SEKCDCINAVRCYHINGGCLCEHGFKGEACDERMCPPGLYGMPCNLRCLCDPLHSQSCHPMSGEC 384

  Fly   379 QCSIGWSSAQCTRPCTFLRYGPNCELTCNCKNGAKCSPVNGTCLCAPGWRGPTCEESCEPGTFGQ 443
            .|..|||...|...|....||.||:..|.|.||..|....|.|:||||:.||.|...|...|:|.
 Frog   385 ACKPGWSGLYCNETCPHGYYGTNCQELCVCLNGGSCDSETGECICAPGFTGPQCSSYCPMETYGP 449

  Fly   444 DCALRCDCQNGAKCEPETGQCLCTAGWKNIKCDRPCDLNHFGQDCAKVCDCHNNAACNPQNGSCT 508
            .|:.:|.|:|...|.|..|.|:|..||:...|..||....:|.:|.:.|:|:|.|:|:|.:|.|:
 Frog   450 KCSQKCGCKNSLACSPIDGSCVCKEGWQKGDCSVPCPKGTWGYNCNRTCECNNGASCSPISGLCS 514

  Fly   509 CAAGWTGERCERKCDTGKFGHDCAQKCQCDFNNSLACDATNGRCVCKQDWGGVHCETNCRSGYYG 573
            |.:||.|::||:.|..|.||..|.|:|:|:  ||..||...|:|.|...|.|..|:.:|..|::|
 Frog   515 CTSGWHGDKCEQPCKDGTFGPGCRQQCECE--NSDNCDPITGQCWCLPGWTGPECKQSCEEGFWG 577

  Fly   574 ENCDKVCRCLNNSSCDPDSGNCICSAGWTGADCAEPCPPGFYGMECKERCPEILHGNKSCDHITG 638
            ..|:..|.|.|.:||.|..|.|.|:||:.|.||...||.|.||.:|...|.  ...:.:|:||.|
 Frog   578 RKCNMTCDCKNGASCSPKDGTCTCAAGFRGPDCDNICPHGRYGKKCVLTCK--CSNHSTCNHIDG 640

  Fly   639 EILCRTGYIGLTCEHPCPAGLYGPGCKLKCNCEHGGECNHVTGQCQCLPGWTGSNCNESCPTDTY 703
            ...|..|:.|..|..||..|.:|..|...|||:|||.|:...|.|.|..||||..|:|.||..:|
 Frog   641 SCKCFPGWKGNDCSEPCTLGFWGKDCASTCNCQHGGHCSPTDGTCICPIGWTGKTCSEVCPLGSY 705

  Fly   704 GQGCAQRCRCVHHKVCRKADGMCICETGWSGTRCDEVCPEGFYGEHCMNTCACPSANFQCHAAHG 768
            |:.|..:|||.:...|....|.|.|..|:.|..|:..||:..||..|...|.|.: |..||...|
 Frog   706 GENCIHKCRCQNGAECDHMTGKCSCLPGYHGAFCEIKCPDRTYGLKCHQVCECLN-NATCHHVTG 769

  Fly   769 -CVCRSGYTGDNCDELIASQRIADQSENSSRASVA----LTLVLMTLFACIIFAVFIYYRRRVSN 828
             |.|.:.:.|.:|::.:..:.......|:..|:.:    :.:|.:.:...::...|:|||....:
 Frog   770 SCQCEAAWFGVHCEKSLNVEVPFTMVPNTPPATDSIGPIIGIVALAILVVVLIGFFLYYRHWQKD 834

  Fly   829 LKTEIAHVHYTHDTNP-------PSWPP---NHNFDNPVYGMQAETRLLPNNMRSK--------- 874
            ..|....|.|: .|.|       |..||   .|.:.||.|...::....|..:.||
 Frog   835 KVTRSLTVAYS-PTRPASSVYEVPDVPPVGYLHYYSNPSYHTLSQCGPCPPPVPSKPERPNSVKM 898

  Fly   875 --MNNF----------------DQRSTMSTDY-------------GDDCNASGRVGSYSINYNHD 908
              ..:|                |..:|:..|:             |...:.|..||.|....||.
 Frog   899 AGKGHFPKVKHPDRERIGGYGTDYNATLPADWKHHGVPLNPRDMGGHRIDRSYSVGVYYNKANHY 963

  Fly   909 LLTKNLNADRTNPIVYNESLKEEHVYDEIKH--------KEG----YKDPV---KIYSKI-LFPE 957
            :....|:..       :.||..|:.|..||.        .||    .|.||   ..|::| ||.|
 Frog   964 VKDSGLSTS-------SSSLNSENPYATIKDFPTLPGKLTEGSYMEMKSPVHREMSYAEIGLFDE 1021

  Fly   958 D-EYDHLDYSRPSTSQKPHYHRMNDAMLNINQDEEKPSNVKNMTVLLNKPLPPT----EPEPQH 1016
            | :|..                      ::.::|..|...:.:|.:....:|||    .|:..|
 Frog  1022 DAQYQQ----------------------DLMEEENFPLGAEGVTTIHRNSVPPTSHYDSPKNSH 1063

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drpr	NP_001261276.1	EMI	26..92	CDD:462204	17/76 (22%)
		EGF_CA	274..319	CDD:473889	20/44 (45%)
		gliding_CglD	<451..579	CDD:468178	50/127 (39%)
		DSL	567..609	CDD:473190	18/41 (44%)
pear1	XP_017952446.2	EMI	28..98	CDD:462204	18/77 (23%)
		EGF_CA	280..325	CDD:473889	20/44 (45%)
		Laminin_EGF	546..586	CDD:395007	14/39 (36%)