Protein Alignment CG13930 and dync2i2

DIOPT Version :10

• Sequence 1: NP_647645.1
• Gene: CG13930 / 38210
• FlyBaseID: FBgn0035256
• Length: 685
• Species: Drosophila melanogaster
• Sequence 2: NP_001099160.1
• Gene: dync2i2 / 794361
• ZFINID: ZDB-GENE-070928-9
• Length: 501
• Species: Danio rerio
• Alignment Length: 537
• Identity: 127/537 - (23%)
• Similarity: 199/537 - (37%)
• Gaps: 101/537 - (18%)

  Fly   142 DELLS--GTDKTRRTVDADTQTMTALMKSRLVNTERLTTAQMGSYVSNFEMYDTYTDLEKSTTSV 204
            ||.|.  |.:.|.|.....||...:.....:..||..|.|:               |:.::.|..
Zfish     4 DETLDLVGAESTWRKSHQQTQESRSCQTRPVHTTETETQAK---------------DVSENGTQT 53

  Fly   205 QVQGAKKMEITTYHVGGVDQFVGINCLPGFRLALMLTMRILASN----VFEPQQRRYRNMAPPDP 265
            |.|..:.:.:..    .:..|.|:  |...|.|..:.:|.|..|    .|:..:..:...
Zfish    54 QDQSGQTLSLDR----DLTDFPGL--LDFMRRAEDVVIRELVKNSKSHAFDGFEVNWEEQ----- 107

  Fly   266 LAEDVKFKYRLGLLWRLSPPSSDPKVHQAVSDMSFCPSNGDIMAVAYGVYSHGKVSKLPRSGWVY 330
             .|.|...|      ||....:..|..|..|....|  .|.::|..:|....|..|.  ....|.
Zfish   108 -NESVSCMY------RLQHVDAQEKSLQVTSVSWNC--TGSVIACGFGRVDDGDWSN--EKACVC 161

  Fly   331 VWNIK----NPVNPERRYHYQVPVVTVEFSPTQPQLLAIGLHNGGVEVRDIS-GQDLPPLAVSQR 390
            .||:.    ||..|:.......||:.:.|.|.:|.::|.||::|.|.|.|.| .||| .||.:..
Zfish   162 TWNVDRQNLNPKRPDVIIDVATPVMCLCFHPVRPSVVAGGLYSGEVVVWDTSRSQDL-ILAQTGM 225

  Fly   391 LSSPYFEPVTAIKWIYFEGDVGCRNPHITPFLATSQAGAVTKYRLINSPNMLGLEQQRLQRAEGE 455
            .:..:.|||..|.|:     .|.|....: .|:....|.|..:.:..|...|.|.
Zfish   226 SADTHREPVYQINWV-----PGARRGEFS-VLSAGSGGRVLLWTIDGSEAKLLLS---------- 274

  Fly   456 LEGIPIERQPPAASLLANRHPQCLEI-----VLDPVQSDIYYVLTDEGTLYKCS----------- 504
             .|..:.||....|..|::....|.|     .|.|...|.:.|.::.|.:.|||
Zfish   275 -SGYALVRQQMPQSGAASKTRGSLTIGVTAVALSPWDLDTFLVGSEGGLVLKCSFSSETAAAVPS 338

  Fly   505 ------TNYPLQHLELRQVHDGPAACMEFSPWSPRMYLTCGSDWCIRIWLAGILLPIVTLQHHLS 563
                  ...|:|.  ......||...:.|||:...::::.|:|....:.......|::.|:...|
Zfish   339 DGESVILRAPMQF--SFSPRGGPIHSVHFSPFHRNLFVSVGTDGLAHLHSVLQPCPLLALRVSDS 401

  Fly   564 PVHCARWSRTHSTILVSLS-RSTVDIWDLRNSTMKPVSSTVIDAD-----IFYTTFKFTHCGRSL 622
            .|...|||.|...:..::: :..|.::||...:::||::  ||.:     .:...|...|. ..|
Zfish   402 YVFGVRWSPTRPLVFAAVTGQGLVQMFDLGRRSLRPVAT--IDQNAGGQPAYCLEFNPKHT-NLL 463

  Fly   623 AVGNEAG--NLLMLSFE 637
            ||||..|  |:..||.|
Zfish   464 AVGNADGSVNIWQLSAE 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13930	NP_647645.1	WD40 repeat	295..344	CDD:293791	13/52 (25%)
		WD40 repeat	350..397	CDD:293791	17/47 (36%)
		WD40 repeat	400..473	CDD:293791	14/72 (19%)
		WD40	442..>629	CDD:441893	48/214 (22%)
		WD40 repeat	478..513	CDD:293791	12/56 (21%)
		WD40	<518..>593	CDD:475233	18/75 (24%)
		WD40 repeat	524..560	CDD:293791	7/35 (20%)
dync2i2	NP_001099160.1	WD40 repeat	130..180	CDD:293791	13/53 (25%)
		WD40	<163..478	CDD:441893	84/337 (25%)
		WD40 repeat	187..229	CDD:293791	16/42 (38%)
		WD40 repeat	235..296	CDD:293791	15/77 (19%)
		WD40 repeat	301..338	CDD:293791	8/36 (22%)
		WD40 repeat	361..399	CDD:293791	7/37 (19%)
		WD40 repeat	403..442	CDD:293791	10/40 (25%)
		WD40 repeat	450..477	CDD:293791	9/27 (33%)