Protein Alignment CG13930 and dync1i2a

DIOPT Version :10

• Sequence 1: NP_647645.1
• Gene: CG13930 / 38210
• FlyBaseID: FBgn0035256
• Length: 685
• Species: Drosophila melanogaster
• Sequence 2: NP_001429003.1
• Gene: dync1i2a / 767729
• ZFINID: ZDB-GENE-060929-1086
• Length: 626
• Species: Danio rerio
• Alignment Length: 699
• Identity: 138/699 - (19%)
• Similarity: 257/699 - (36%)
• Gaps: 155/699 - (22%)

  Fly     6 RKDYRTADFEQLSRMIRDHPLMKE--------PGAEQQQLHKLRTPEYRTKCVMRASLDDI--AL 60
            ||..|.|...:..:...:....||        |..:...|.|           .|...|.:  ::
Zfish    13 RKKQRLAQIREEKKRKEEERKKKEAELKKDAVPLQDDSDLEK-----------KRREADALLQSM 66

  Fly    61 GINLYKLQLDTPMSPTLEEPNYLKEPAS--------SARSAHSARPPATPFIKVLLRKTPIVVLF 117
            ||.........|||||.:......|..|        ..|:.|....|:|..:...|.:.|:
Zfish    67 GITSDVSAAPAPMSPTAKSVGSPSEAGSQDSGDGTTGPRTLHWDCDPSTVLLHSELGRGPL---- 127

  Fly   118 ERRSMTALADTEEGRQVMEDNRKYDELLSGTDKTRRTVDADTQTMTALMKSRLVNTERLTTAQMG 182
             :.:||.:...:...:         |::|.|.:|:      |.|||. .|......|....||.
Zfish   128 -KLAMTKMTHVDFPPK---------EVVSYTKETQ------TPTMTE-QKDEEDEEEETPAAQP- 174

  Fly   183 SYVSNFEMYDTYTDLEKSTTSVQVQGAKKMEIT---TYHVGGVDQFVGINCLPGFRLALMLTMRI 244
                     :..|:.||.... ||:.|...|:|   ...:...::|:..     |..:..:..|.
Zfish   175 ---------EAETEKEKPEEK-QVEEALPHELTEEEKLQILHSEEFMDF-----FDHSTRIVERA 224

  Fly   245 LASNVFEPQQRRYRNMAPPDPLAEDVKFKY------------RLGLLWRLSPPSSDPK--VHQAV 295
            |:.:|                   ||.|.|            :.|....|:....|.:  ..:.|
Zfish   225 LSEHV-------------------DVFFDYSGRDMEEKEGEMQAGTKLSLNRKFVDDRWSKQRVV 270

  Fly   296 SDMSFCPSNGDIMAVAYGVYSHGKVSKLPRSGWVYVWNIK-NPVNPERRYHYQVPVVTVEFSPTQ 359
            :.:.:.|...:::..:   |::.:.:.....|...|||:| ....||..:|.|..|::..|:...
Zfish   271 TCLDWSPQYPELLVAS---YNNNEEAPHEPDGVALVWNMKYKKATPEYVFHCQSAVMSAAFAKFH 332

  Fly   360 PQLLAIGLHNGGVEVRDISGQDLPPLAVSQRLSSPYFEPVTAIKWIYFEGDVGCRNPHITPFLAT 424
            |.|:..|.::|.:.:.|.......|:..:...::.:..||      |....||.:|.|  ..::.
Zfish   333 PNLVVGGTYSGQIVLWDNRSNRRTPVQRTPLSAAAHTHPV------YCVNVVGTQNAH--NLISI 389

  Fly   425 SQAGAVTKYRLINSPNMLGLEQQRLQRAEGELEGIPIERQPPAASLLANRHPQCLEIVLDPVQSD 489
            |..|.:..:.|    :||...|..::.         :.:|..:.::.:...|      |..|.:
Zfish   390 STDGKMCSWSL----DMLSQPQDSMEL---------VFKQSKSVAVTSMSFP------LGDVNN- 434

  Fly   490 IYYVLTDEGTLYKCSTNYPLQHL-ELRQVHDGP---------AACMEFSPWSPRMYLTCGSDWCI 544
             :.|.:::|::|..|.:.....: |:.:.|.||         |..::||    .::||...||.:
Zfish   435 -FVVGSEDGSVYTASRHGSRAGISEMFEGHHGPITGIHCHTAAGPVDFS----HLFLTASFDWTV 494

  Fly   545 RIWLAGILLPIVTLQHHLSPVHCARWSRTHSTILV---SLSRSTVDIWDLRNSTMKPVSSTVIDA 606
            ::|......|:.:.:.:...|:...||..|..:..   .|.|  ||:|:|.|.|..|.:|..:|.
Zfish   495 KLWSNKNNKPLYSFEDNSDYVYDVMWSPVHPALFACVDGLGR--VDLWNLNNDTEVPTASVAVDG 557

  Fly   607 DIFYTTFKFTHCGRSLAVGNEAGNLLMLSF-EDMPFPPHFQYKQLKRAI 654
            .......:::..||.:|||:..|.:.:... |.:..|.:.::.:..|.:
Zfish   558 SPALNRLRWSQSGREIAVGDSEGQIHIYDVGEQIAVPRNDEWTRFVRTL 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13930	NP_647645.1	WD40 repeat	295..344	CDD:293791	10/49 (20%)
		WD40 repeat	350..397	CDD:293791	8/46 (17%)
		WD40 repeat	400..473	CDD:293791	12/72 (17%)
		WD40	442..>629	CDD:441893	43/199 (22%)
		WD40 repeat	478..513	CDD:293791	6/35 (17%)
		WD40	<518..>593	CDD:475233	22/86 (26%)
		WD40 repeat	524..560	CDD:293791	8/35 (23%)
dync1i2a	NP_001429003.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..108		17/98 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	142..197		19/81 (23%)
		WD 1. /evidence=ECO:0000255	265..314		8/51 (16%)
		WD 2. /evidence=ECO:0000255	318..358		9/39 (23%)
		WD 3. /evidence=ECO:0000255	367..408		12/52 (23%)
		WD 4. /evidence=ECO:0000255	417..457		7/47 (15%)
		WD 5. /evidence=ECO:0000255	462..507		12/48 (25%)
		WD 6. /evidence=ECO:0000255	510..550		12/41 (29%)
		WD 7. /evidence=ECO:0000255	556..595		8/38 (21%)