Protein Alignment CG13930 and Dnai1

DIOPT Version :10

• Sequence 1: NP_647645.1
• Gene: CG13930 / 38210
• FlyBaseID: FBgn0035256
• Length: 685
• Species: Drosophila melanogaster
• Sequence 2: NP_780347.2
• Gene: Dnai1 / 68922
• MGIID: 1916172
• Length: 701
• Species: Mus musculus
• Alignment Length: 698
• Identity: 144/698 - (20%)
• Similarity: 265/698 - (37%)
• Gaps: 167/698 - (23%)

  Fly    14 FEQLSRMIRDHPLMKEPGAEQQQLHKLRTPEYRTKCVMRASLDDIALGINLYKLQLDTPMSPTLE 78
            |.|:..:|   |...:.|..|         .||         |::..| :...:::.|..:..||
Mouse    97 FSQVGNLI---PKDSDEGRRQ---------HYR---------DEMVAG-SQESIKVVTSEAENLE 139

  Fly    79 EPNYLKEPASSARSAHSARPPATPFIKVLLRKTPIVVLFERRSMTALADTEEGRQVMEDNRKYDE 143
            |....||....|.:...|.                    .:..:.|.|:|.|  :|:|     :|
Mouse   140 EEEEPKEGEGEAEAEAEAG--------------------SQTDIPAAAETTE--KVIE-----EE 177

  Fly   144 LLSGTDKTRRTV-------DADTQTMTALMKSRLVNTERLTTAQMGSYVSNFEMYDTYTD-LEKS 200
            |::......|.:       :..:||....::.|....|........:..:.:|:||.|.| |||.
Mouse   178 LMAPVQPKERKLTNQFNFSERASQTFNNPLRDRECQMEPPPRTNFSATANQWEIYDAYVDELEKQ 242

  Fly   201 TTSVQVQGAKKMEITTYHVGGVDQFVGINCLPGFRLALMLTMRILASNVFEPQQ----------- 254
            ..:.:.:.||                    .|..:....:.||.|.|  .|.|.
Mouse   243 EKTKEKEKAK--------------------TPVAKKTEKMAMRKLTS--MESQSDDITKVTQAAK 285

  Fly   255 --RRYRNMAPPDPLAEDVKF------KYR-----LGLLWRLSPPSSDPKVHQAVSDMSFCPSNGD 306
              .|..|....|.:|:|.|:      :||     |..||:.   .:|.....||:.:.:.|...|
Mouse   286 IVERMVNQNTYDDVAQDFKYYEDTADEYRDQEGTLLPLWKF---QNDKAKRLAVTALCWNPKYKD 347

  Fly   307 IMAVAYGVYSHGKVSKLPRSGWVYVWNIKNPVNPERRYHYQVPVVTVEFSPTQPQLLAIGLHNGG 371
            :.||.:|.|...|.|:    |.:.::::|||..||..:..:..::.::.....|.|:.:|.::|.
Mouse   348 LFAVGHGSYDFMKQSR----GMLLLYSMKNPSFPEYMFSSESGIMCLDVHVDHPYLVVVGYYDGN 408

  Fly   372 VEVRDISGQDLPPLAVSQRLSSPYFEPVTAIKWIYFEGDVGCRNPHITPFLATSQAGAVTKYRLI 436
            |.:.::......|...|...|..:.:||..:||...:.|      |...|.:.|..|.:..:.|:
Mouse   409 VAIYNLKKPHSQPCFRSTSKSGKHTDPVWQVKWQKDDMD------HNLNFFSVSSDGRIVSWTLV 467

  Fly   437 NSPNMLGLEQQRLQRAEGELEGIP--IERQPPAASLLANRHPQCLEIVLDPVQSDIYYVLTDEGT 499
            .| .::.::..:| :.||....||  ::..........:.|.:.         ..::.|.|:||.
Mouse   468 KS-ELVHIDIIKL-KTEGSTTEIPEGLQLHTVGCGTAFDFHKEI---------DYMFLVGTEEGK 521

  Fly   500 LYKCSTNYPLQHLELRQVHDGPAACMEFSPWSPRMYLTCGSDWCIRIWLAGILLPIVTLQHHLSP 564
            :||||.:|..|.|:....|:.....:.::|:..:::::|.|||.::||...|..|:.....: |.
Mouse   522 IYKCSKSYSSQFLDTYDAHNMAVDAVLWNPYHTKVFMSCSSDWTVKIWDHTIKTPMFIYDLN-SA 585

  Fly   565 VHCARWSRTHSTILVSLSRSTVD----IWDLRNSTMKPVSSTVIDA----DIFYTTFKFTHCGRS 621
            |....|:...||:..::   |.|    ::||..:..:.:.:..:.|    .|.:..|...|  ..
Mouse   586 VGDVAWAPYSSTVFAAV---TTDGKAHVFDLAVNKYEAICNQPVVAKKKNKITHVQFNPIH--PI 645

  Fly   622 LAVGNEAGNLLMLSFEDMPFPPHFQYKQLKRAIFKALSMQPDLRKQVK 669
            :.||::.|:::                        .|.:.|:|||..|
Mouse   646 IIVGDDRGHII------------------------CLKLSPNLRKMPK 669

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13930	NP_647645.1	WD40 repeat	295..344	CDD:293791	15/48 (31%)
		WD40 repeat	350..397	CDD:293791	8/46 (17%)
		WD40 repeat	400..473	CDD:293791	14/74 (19%)
		WD40	442..>629	CDD:441893	42/196 (21%)
		WD40 repeat	478..513	CDD:293791	10/34 (29%)
		WD40	<518..>593	CDD:475233	19/78 (24%)
		WD40 repeat	524..560	CDD:293791	9/35 (26%)
Dnai1	NP_780347.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..45
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	119..165		9/66 (14%)
		WD40 repeat	336..382	CDD:293791	15/49 (31%)
		WD40	<354..612	CDD:475233	63/282 (22%)
		WD 1	382..422		5/39 (13%)
		WD40 repeat	388..429	CDD:293791	7/40 (18%)
		WD 2	431..474		11/49 (22%)
		WD40 repeat	436..493	CDD:293791	15/64 (23%)
		WD40 repeat	501..538	CDD:293791	12/45 (27%)
		WD 3	539..579		10/39 (26%)
		WD40 repeat	544..581	CDD:293791	9/36 (25%)
		WD 4	581..621		9/43 (21%)
		WD40 repeat	586..627	CDD:293791	8/43 (19%)
		WD 5	629..668		11/64 (17%)