Protein Alignment CG13930 and dync1i1b

DIOPT Version :10

• Sequence 1: NP_647645.1
• Gene: CG13930 / 38210
• FlyBaseID: FBgn0035256
• Length: 685
• Species: Drosophila melanogaster
• Sequence 2: XP_005158174.1
• Gene: dync1i1b / 561525
• ZFINID: ZDB-GENE-061215-62
• Length: 645
• Species: Danio rerio
• Alignment Length: 714
• Identity: 147/714 - (20%)
• Similarity: 254/714 - (35%)
• Gaps: 187/714 - (26%)

  Fly     6 RKDYRTADFEQLSRMIRDHPLMKEPGAEQQQLHKLRTPEY--------RTKCVMRASLDDIALGI 62
            ||..|.|       .||:....||...::::...|:.||.        |.:....|.|..|  ||
Zfish    13 RKKQRLA-------QIREEKKRKEEERKKKESEMLQRPENVTEDSDLDRKRRETEALLQSI--GI 68

  Fly    63 N-----LYKLQL------------DTPMSPTLEEPNYLKEPASSARSAHSARPPATPFIKVLLRK 110
            :     :..|||            .|||||                |:.|..||
Zfish    69 SPEPPLVQPLQLLTWDTCYFHYLVPTPMSP----------------SSQSVSPP----------- 106

  Fly   111 TPIVVLFERRSMTALADTEEGRQVMEDNRKYDELLS-GTDKTRRTVDADT------QTMTA---- 164
                             :|.|.|...|....:..|. .||.:...:.||:      |.:.|
Zfish   107 -----------------SETGSQESIDGGTVERTLQWDTDPSALQLLADSVHGCRMQRLGASKIV 154

  Fly   165 ---LMKSRLVNTERLTTAQMGSYVSNFEMYDTYTDLEKSTTSVQVQGAKKMEITTYHVGGV---- 222
               .|...||...:.|...:.|.....|..:..:..:....|.|::..|..|:...|...:
Zfish   155 QIDFMPKELVTYSKETQTPVASNQPEEEDDEELSVPKSEPASQQLEEEKTQEVEEVHPRELTNEE 219

  Fly   223 -DQFV-GINCLPGFRLALMLTMRILASNVFEPQQRRYRNMAPPDPLAEDVKFKY-------RLGL 278
             :|.| ..:.|..|..::.:..|:||.:                   :|:.|.|       :.|.
Zfish   220 KEQIVHSEDFLFFFDRSIRVVERVLAED-------------------KDIFFDYSGRDMEDKEGD 265

  Fly   279 LWRLSPPSSDP-------KVHQAVSDMSFCPSNGDIMAVAYGVYSHGKVSKLPR--SGWVYVWNI 334
            |...|..|.:.       ..|:.|:.:.:.|...:::..:|......     |.  .|.|.|||:
Zfish   266 LQAGSNLSFNRHFYDEHWSKHRVVTSLDWSPQYPELLVASYNTNEDA-----PHEPDGVVLVWNM 325

  Fly   335 K-NPVNPERRYHYQVPVVTVEFSPTQPQLLAIGLHNGGVEVRDISGQDLPPLAVSQRLSSPYFEP 398
            | ....||..:|.|..|::|.|:...|.|:..|.::|.:.:.|.......|:..:...::.:..|
Zfish   326 KFKKATPEYIFHCQSSVMSVGFAQFHPNLVIGGTYSGQIAMWDNRSHRRTPVQRTPLSATAHTHP 390

  Fly   399 VTAIKWIYFEGDVGCRNPHITPFLATSQAGAVTKYRLINSPNMLGLEQQRLQRAEGELEGIPIER 463
            |      |....||.:|.:  ..:..|..|.:..:.|    :||...|:       .:|.|..:.
Zfish   391 V------YCVNVVGTQNAN--NLITVSTDGKMCSWSL----DMLSQPQE-------SMELIYNKS 436

  Fly   464 QPPAASLLANRHPQCLEIVLDPVQSDI--YYVLTDEGTLYKCSTNYPLQHL-ELRQVHDGPA--- 522
            :|.|.:.:|  .|          .||:  |.|.::|||:|..|.:.....: |:...|.||.
Zfish   437 KPVAVTCMA--FP----------ASDVNNYVVGSEEGTVYTASRHGSKAGIGEIFDGHQGPVTGI 489

  Fly   523 AC------MEFSPWSPRMYLTCGSDWCIRIWLAGILLPIVTLQHHLSPVHCARWSRTHSTILVSL 581
            :|      ::||    .::.|...||.:::|......|:.:.:.:...|:...||..|..:..::
Zfish   490 SCHNAVGPVDFS----HLFTTSSFDWTVKLWSTKHNKPLYSFEDNADYVYDVMWSPVHPALFATV 550

  Fly   582 -SRSTVDIWDLRNSTMKPVSSTVIDADIFYTTFKFTHCGRSLAVGNEAGNLLMLSFEDMPFPPH 644
             ....:|:|:|.|.|..|.:|..::........::...||.:|||:..|.:.:....:....||
Zfish   551 DGNGRLDLWNLNNYTEVPSASVSVEGGCALNRVRWASGGREVAVGDSEGRVWIYDVGEQLAVPH 614

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13930	NP_647645.1	WD40 repeat	295..344	CDD:293791	12/51 (24%)
		WD40 repeat	350..397	CDD:293791	9/46 (20%)
		WD40 repeat	400..473	CDD:293791	14/72 (19%)
		WD40	442..>629	CDD:441893	45/199 (23%)
		WD40 repeat	478..513	CDD:293791	9/37 (24%)
		WD40	<518..>593	CDD:475233	18/84 (21%)
		WD40 repeat	524..560	CDD:293791	8/41 (20%)
dync1i1b	XP_005158174.1	Dynein_IC2	143..173	CDD:463291	6/29 (21%)
		WD40	286..625	CDD:441893	82/369 (22%)
		WD40 repeat	290..335	CDD:293791	11/49 (22%)
		WD40 repeat	345..386	CDD:293791	8/40 (20%)
		WD40 repeat	392..435	CDD:293791	12/55 (22%)
		WD40 repeat	441..488	CDD:293791	15/58 (26%)
		WD40 repeat	496..528	CDD:293791	7/35 (20%)
		WD40 repeat	534..572	CDD:293791	10/37 (27%)
		WD40 repeat	580..606	CDD:293791	6/25 (24%)