Protein Alignment CG13930 and LOC4576277

DIOPT Version :10

• Sequence 1: NP_647645.1
• Gene: CG13930 / 38210
• FlyBaseID: FBgn0035256
• Length: 685
• Species: Drosophila melanogaster
• Sequence 2: XP_001237748.2
• Gene: LOC4576277 / 4576277
• VectorBaseID: AGAMI1_000491
• Length: 693
• Species: Anopheles gambiae
• Alignment Length: 611
• Identity: 262/611 - (42%)
• Similarity: 360/611 - (58%)
• Gaps: 34/611 - (5%)

  Fly    79 EPNYLKEPASSARSAHSARPPATPFIKVLLRKTPIVVLFERRSMTALADTEEGRQVMEDNRKYDE 143
            :|||  |.....||........|..:|:.|.:|..:||||..|.....|.||..:|.|.||:::.
Mosquito   104 QPNY--EGVIDRRSPSLEAGQKTYHVKIRLTETDDIVLFESPSHVVSLDAEEAARVQEQNRRFET 166

  Fly   144 LLSGTDKTRRTVDADTQTMTALMKSRLVNTERLTTAQMGSYVSNFEMYDTYTDLEKSTTSVQV-Q 207
                ..|.|||.||:.||.....|||.||||.:....:.|:|||::|||||.|||:.|..:.| .
Mosquito   167 ----RPKARRTADAEAQTRDLPCKSRSVNTECIHRQDVASFVSNYDMYDTYNDLERHTKEINVAD 227

  Fly   208 GAKKMEITTYHVGG---VDQFVGINCLPGFRLALMLTMRILASNVFEPQQRRYRNMAPPDPLAED 269
            .|.|:|||||...|   :|:.:..|.  .|.|:.|:..|:||.||:..||.|:|||.||||..||
Mosquito   228 SASKLEITTYSREGMEDIDERLNRNA--NFHLSSMILQRLLAGNVYREQQIRFRNMYPPDPCRED 290

  Fly   270 VKFKYRLGLLWRLSPPSSDPKVHQAVSDMSFCPSNGDIMAVAYGVYSH-GKVSKLPRSGWVYVWN 333
            :::.|||.:||......:   :.:.|:..|:||:||||:|:|||:|.| |...:  ..|:|||||
Mosquito   291 IRYLYRLDVLWTYRTVET---LGKPVASASWCPANGDIVALAYGIYGHTGSDDR--GCGFVYVWN 350

  Fly   334 IKNPVNPERRYHYQVPVVTVEFSPTQPQLLAIGLHNGGVEVRDISGQDLPPLAVSQRLSSPYFEP 398
            |||||||||||.:..||..|.||...|||||:||::|.|:||||:.....|||||.|...|.::|
Mosquito   351 IKNPVNPERRYRFDCPVTCVAFSRRTPQLLAVGLYDGRVQVRDITDTTQTPLAVSNRDRFPVYQP 415

  Fly   399 VTAIKWIYFEGDVGCRNPHITPFLATSQAGAVTKYRLINSPNMLGLEQQRLQRAEGELEG----- 458
            :..:||:.|:      |......:|.||.|.|.||.|.....:|.....||.|.||..||
Mosquito   416 IWDLKWVEFD------NEGKDEVIAVSQNGWVMKYTLTIGQYLLPYPLLRLDRVEGTPEGQTSTG 474

  Fly   459 --IPIERQPPAASLLANRHPQCLEIVLDPVQSDIYYVLTDEGTLYKCSTNYPLQHLELRQVHDGP 521
              .|.::||  ..:.::.|||.|.:.:.|||.|.||:.||||.::.||.|.|.|||.:.|:|...
Mosquito   475 TSAPADQQP--VRVQSDLHPQALCVTIHPVQKDKYYIGTDEGAVHWCSINDPFQHLGVLQMHSRG 537

  Fly   522 AACMEFSPWSPRMYLTCGSDWCIRIWLAGILLPIVTLQHHLSPVHCARWSRTHSTILVSLSRSTV 586
            ..|:|:||||||::|||..||.||||:..:..|||||....:|:..|.||.|:||::.|::||.|
Mosquito   538 IFCLEYSPWSPRIFLTCSGDWSIRIWIEELPEPIVTLCTGFAPIQAAYWSPTNSTVIASVTRSGV 602

  Fly   587 DIWDLRNSTMKPVSSTVIDA-DIFYTTFKFTHCGRSLAVGNEAGNLLMLSFEDMPFPPHFQYKQL 650
            .:|||:..:.||.|.|.:.: ....|..:||:|||.|.||:..|...:.:.|||||||||||::|
Mosquito   603 QLWDLKRRSSKPASETTLGSLTTALTVVRFTNCGRCLLVGDAEGKAHVCALEDMPFPPHFQYREL 667

  Fly   651 KRAIFKALSMQPDLRKQVKSVGYFGY 676
            :.|::..|...|:|..:||.:||.||
Mosquito   668 QSALYGKLVTTPELLTRVKRMGYLGY 693

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13930	NP_647645.1	WD40 repeat	295..344	CDD:293791	30/49 (61%)
		WD40 repeat	350..397	CDD:293791	24/46 (52%)
		WD40 repeat	400..473	CDD:293791	23/79 (29%)
		WD40	442..>629	CDD:441893	83/194 (43%)
		WD40 repeat	478..513	CDD:293791	17/34 (50%)
		WD40	<518..>593	CDD:475233	37/74 (50%)
		WD40 repeat	524..560	CDD:293791	22/35 (63%)
LOC4576277	XP_001237748.2	WD40	<294..650	CDD:441893	159/368 (43%)
		WD40 repeat	368..406	CDD:293791	20/37 (54%)
		WD40 repeat	416..489	CDD:293791	23/80 (29%)
		WD40 repeat	497..533	CDD:293791	17/35 (49%)
		WD40 repeat	538..574	CDD:293791	20/35 (57%)
		WD40 repeat	581..621	CDD:293791	17/39 (44%)
		WD40 repeat	627..664	CDD:293791	19/36 (53%)