Protein Alignment CG13930 and dync2i2

DIOPT Version :10

• Sequence 1: NP_647645.1
• Gene: CG13930 / 38210
• FlyBaseID: FBgn0035256
• Length: 685
• Species: Drosophila melanogaster
• Sequence 2: XP_012823678.1
• Gene: dync2i2 / 448417
• XenbaseID: XB-GENE-953027
• Length: 503
• Species: Xenopus tropicalis
• Alignment Length: 518
• Identity: 103/518 - (19%)
• Similarity: 181/518 - (34%)
• Gaps: 140/518 - (27%)

  Fly   152 RRTVDADTQTMTALMKSRLVNTERLTTAQMGSYVSNFEMYDTYTDLEKSTTSVQVQGAKKMEITT 216
            :||:|.|...:             |....:|.::...|.. ...:|.|:..|....|
 Frog    59 QRTLDVDLGPL-------------LDYPDLGQFLKRVEGI-MIKELNKNWKSHAFDG-------- 101

  Fly   217 YHVGGVDQFVGINCLPGFRLALMLTMRILASNVFEPQQRRYRNMAPPDPLAEDVKFKYRLGLLWR 281
            |.|...:|...:.||                          .::..||.|.:.::
 Frog   102 YEVNWEEQHEQVTCL--------------------------HSLQYPDALEQQLQ---------- 130

  Fly   282 LSPPSSDPKVHQAVSDMSFCPSNGDIMAVAYGVYSHGKVSKLPRSGWVYVWNIK----NPVNPER 342
                         |:.:|: .|.|.|:|.:||.:..|..|  ....:|..||:.    |..||:.
 Frog   131 -------------VTSVSW-NSTGSIIACSYGRFGDGDWS--TEKSYVCTWNLDRRGFNANNPDT 179

  Fly   343 RYHYQVPVVTVEFSPTQPQLLAIGLHNGGVEVRDISGQDLPPLAVSQRLSSPYFEPVTAIKWIYF 407
            .......|:.:.:.|:||.|:|.||.||.|.|.|.|..|.|.:..:..:...:.:.|..:.|:.
 Frog   180 VLDVPSSVMCLAWHPSQPSLIAGGLFNGDVLVWDTSRTDDPLIGRTGHVGDTHTDAVYQVGWMQ- 243

  Fly   408 EGDVGCRNPHITPFLATSQAGAVTKYRLINSPNMLGLEQQRLQRAEGELEGIPIERQPPA----- 467
            |...|    |.....:.|..|.:..:::....:::.|:...|           :.:|.|:
 Frog   244 EKSQG----HRHQVFSVSSDGKILVWQMEKEGHLVLLDGFAL-----------VAQQIPSNTKIH 293

  Fly   468 ----------ASLLANRHPQCLEIVLDPVQSDIYYVLTDEGTLYKCSTNY----PL---QHLELR 515
                      .:.|:..|       .||   .::.|..:.|.|.|||::.    |:   ..:.||
 Frog   294 KPGRGDTAVGVTCLSYSH-------FDP---SLFIVGVEGGYLLKCSSSVQTLAPINMGSSVPLR 348

  Fly   516 -------QVHDGPAACMEFSPWSPRMYLTCGSDWCIRIWLAGILLPIVTLQHHLSPVHCARWSRT 573
                   ..|.||...:..||:...::|:.|:|....::......|:|:||.....:...|||..
 Frog   349 APAQFTFSPHGGPVYSVTCSPFHRNLFLSAGTDGHAHLYSMLQAKPLVSLQLSQKYLFSIRWSPV 413

  Fly   574 HSTILVSLS-RSTVDIWDLRNSTMKP---VSSTVIDADIFYTTFKFTHC-GRSLAVGNEAGNL 631
            ...:..:.| ...|.:.|...|..||   :..|.....::  ..:|.|. .:.||.|:..|.:
 Frog   414 RPLVFAAASGDGEVVLVDFAKSFQKPSLCIKQTASGRPVY--CLEFNHAQSQLLAAGDGTGTV 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13930	NP_647645.1	WD40 repeat	295..344	CDD:293791	16/52 (31%)
		WD40 repeat	350..397	CDD:293791	16/46 (35%)
		WD40 repeat	400..473	CDD:293791	11/87 (13%)
		WD40	442..>629	CDD:441893	44/220 (20%)
		WD40 repeat	478..513	CDD:293791	9/41 (22%)
		WD40	<518..>593	CDD:475233	18/75 (24%)
		WD40 repeat	524..560	CDD:293791	8/35 (23%)
dync2i2	XP_012823678.1	WD40	<131..481	CDD:441893	84/375 (22%)
		WD40 repeat	131..182	CDD:293791	16/53 (30%)
		WD40 repeat	188..227	CDD:293791	15/38 (39%)
		WD40 repeat	236..297	CDD:293791	11/76 (14%)
		WD40 repeat	305..355	CDD:293791	13/59 (22%)
		WD40 repeat	362..399	CDD:293791	7/36 (19%)
		WD40 repeat	405..446	CDD:293791	9/40 (23%)
		WD40 repeat	452..477	CDD:293791	6/25 (24%)