Protein Alignment CG13930 and Dnai4

DIOPT Version :10

• Sequence 1: NP_647645.1
• Gene: CG13930 / 38210
• FlyBaseID: FBgn0035256
• Length: 685
• Species: Drosophila melanogaster
• Sequence 2: NP_001019957.1
• Gene: Dnai4 / 313417
• RGDID: 1311027
• Length: 803
• Species: Rattus norvegicus
• Alignment Length: 643
• Identity: 155/643 - (24%)
• Similarity: 272/643 - (42%)
• Gaps: 86/643 - (13%)

  Fly    73 MSPTLEEPNYLKEPASSARSAHSARPPATPFI---------KVLLRKTPIVVLFERRSMTALADT 128
            |:..||:|:|.::..:|.......|.||...|         ::.|.:|..:..|:..::....|:
  Rat   156 MTEDLEDPSYKRDRLASFADVRVMRAPAEAAITKEELERNVEIFLMETETLRFFDLPTVMISTDS 220

  Fly   129 EEGRQVMEDNRKYDELLSGTDKTRRTVDADTQTMTALMKSRLVNTERLTTAQMGSYVSNFEMYDT 193
            ||..:|:|.|..|:.|..........|:...||.....|::.|..:::...:.|...:.:::||:
  Rat   221 EEAEKVIEKNINYEILCRNRLGNDLYVERMMQTFNGAPKNKDVQCDKIIMEEKGVMATTWDLYDS 285

  Fly   194 YTDLEKS-------------------------TTSVQVQGAKKMEITTYHVGGVDQFVGINCLPG 233
            :...|.|                         :.|..:...:.:.:...|....|....|.....
  Rat   286 FNIPEASLAAKRSAYLSKASLLVRDRDPKIQDSESSSLMDIESVILAKSHEDEEDNSEKILKSDK 350

  Fly   234 FRLALMLTMRILASNVFEPQQRRYR--------------------NMAPPDPLAEDVKFKYRLGL 278
            ....|....|:|..|||:|:...||                    |....|.:.:|.:.:....|
  Rat   351 LHQDLFYMERVLMENVFQPKLAAYRQLPIYKELEPGQPEEDLQVVNKVTEDEVKKDEEEEMETEL 415

  Fly   279 --------------LWRLSPPSSDPKVHQAVSDMSFCPSNGDIMAVAYGVYSHGKVSKLPRSGWV 329
                          |.||...|.|......||.:|:..:|.|::||.||.:..    |..:.|..
  Rat   416 EIEITTEQSTIPANLERLWSFSCDLTKGLNVSSLSWNKANSDLLAVGYGNFGF----KEQKRGMA 476

  Fly   330 YVWNIKNPVNPERRYHYQVPVVTVEFSPTQPQLLAIGLHNGGVEVRDISGQDLPPLAVSQRLSSP 394
            ..|:||||:.|||.|.....|.:|:||.:.|.|||:|.|||.|.:.::......|:..|......
  Rat   477 CCWSIKNPMWPERIYQSPYGVTSVDFSISSPNLLAVGYHNGTVAIYNVQSNHNTPVLDSSESPQK 541

  Fly   395 YFEPVTAIKWIYFEGDVGCRNPHITPFLATSQA-GAVTKYRL---INSPNMLGLEQQRLQRAEGE 455
            :..||..::||  |.|.|.........|.:..| |.::|:.:   ::..:::.|::..:..::
  Rat   542 HLGPVWQVQWI--EQDRGTTGDDRREILVSISADGRISKWVIRKGLDCHDLMHLKRTTVTSSK-- 602

  Fly   456 LEGIPIERQPPAASLLANRHP-QCLEIVLDPVQSDIYYVLTDEGTLYKCSTNYPLQHLELRQVHD 519
             :|  ||::....:|::.:.| .|  .......::||...|:||.::|||.:|..|:||..:.|.
  Rat   603 -KG--IEKEKKGEALISRQAPGMC--FAFHTKDTNIYLAGTEEGLIHKCSCSYNEQYLETYRGHK 662

  Fly   520 GPAACMEFSPWSPRMYLTCGSDWCIRIWLAGILLPIVTLQHHLSPVHCARWSRTHSTILVSLSRS 584
            ||...:.::|:.|.::|:|.:||.:.||....:.|..|.......|:...||...:.|..:.:.:
  Rat   663 GPVYKVTWNPFCPDVFLSCSADWGVMIWHQDNVKPFFTFYPTTYVVYDVAWSPKSAYIFAAANEN 727

  Fly   585 TVDIWDLRNSTMKPVSSTVIDADIFYTTFKFTHCGRSLAVGNEAGNLLMLSFEDMPFP 642
            .|:||||:.||:.|:...|.:..|.:||..|......|.||:..|.:.:....:||.|
  Rat   728 RVEIWDLQISTLDPLIVNVANPGIKFTTVLFAKQTDCLLVGDSDGQVAVYELRNMPTP 785

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13930	NP_647645.1	WD40 repeat	295..344	CDD:293791	19/48 (40%)
		WD40 repeat	350..397	CDD:293791	15/46 (33%)
		WD40 repeat	400..473	CDD:293791	14/76 (18%)
		WD40	442..>629	CDD:441893	52/187 (28%)
		WD40 repeat	478..513	CDD:293791	11/34 (32%)
		WD40	<518..>593	CDD:475233	22/74 (30%)
		WD40 repeat	524..560	CDD:293791	10/35 (29%)
Dnai4	NP_001019957.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..41
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	88..109
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	143..163		3/6 (50%)
		WD40 repeat	447..492	CDD:293791	18/48 (38%)
		WD 1. /evidence=ECO:0000255	492..532		13/39 (33%)
		WD40	496..778	CDD:475233	79/290 (27%)
		WD40 repeat	497..541	CDD:293791	15/43 (35%)
		WD 2. /evidence=ECO:0000255	541..589		11/49 (22%)
		WD40 repeat	547..616	CDD:293791	14/75 (19%)
		WD 3. /evidence=ECO:0000255	616..656		12/41 (29%)
		WD40 repeat	621..659	CDD:293791	13/39 (33%)
		WD 4. /evidence=ECO:0000255	660..700		12/39 (31%)
		WD40 repeat	666..701	CDD:293791	9/34 (26%)
		WD 5. /evidence=ECO:0000255	703..742		11/38 (29%)
		WD40 repeat	708..740	CDD:293791	11/31 (35%)
		WD 6. /evidence=ECO:0000255	748..787		11/38 (29%)
		WD40 repeat	750..779	CDD:293791	8/28 (29%)