DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG13930 and Dnai3

DIOPT Version :10

Sequence 1:NP_647645.1 Gene:CG13930 / 38210 FlyBaseID:FBgn0035256 Length:685 Species:Drosophila melanogaster
Sequence 2:NP_766452.2 Gene:Dnai3 / 242253 MGIID:3045269 Length:923 Species:Mus musculus


Alignment Length:868 Identity:158/868 - (18%)
Similarity:280/868 - (32%) Gaps:318/868 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly    12 ADFEQLSRMIRDHPLMKEPGAEQQQLHKLRTPEYRTKCVMRASLDDIALGINLYKLQLDTPMSPT 76
            :||..:.:::|::     ||.|...::.                .|...|:|.|.:..:.     
Mouse    88 SDFHPVKKIVREY-----PGEELLLVYD----------------KDFKYGLNFYLIGTED----- 126

  Fly    77 LEEPNYLKEPASSARSAHSARPPATPFIKVLLRKTPIVVLFERRSMTALADTEEGRQ-VMEDNRK 140
             .:.|:||             ||..|                       .:.||.:: |.||...
Mouse   127 -GKENFLK-------------PPEVP-----------------------EEQEEPKEHVQEDVYV 154

  Fly   141 YDELLS------GTDK--TRRTVDADTQTMTALMKSR-------LVNTERLTTAQMGSYV----- 185
            |:..:|      |::|  ...:|....:.:|.::..:       :..:::..::...:|:     
Mouse   155 YNPPVSKPWVSLGSEKEIEEESVQESGKRVTYMISRKRSEFGAPVTFSDQNASSVKDAYIECTSY 219

  Fly   186 --SNFEMYDTYTDL------EKSTTSVQVQGAKKMEITTYH------------VGGVDQFVGI-- 228
              .|:.:.....|:      |...||.|.:.|.....||.:            :|.....|..  
Mouse   220 PEKNYTLSQVEKDVGLQVIAEVKDTSTQTKWAFPKNATTQYYPREFSEEEKSLIGKSKSLVDFFN 284

  Fly   229 NCLPGFRLALMLTMRILASNVFEPQQRRYRNMAPPDPLAEDVKFKYRLGLLWRLSPPSSDPKVHQ 293
            |......:||... .|:  |.|...   ::|:|..:....|....:       |....|...:|.
Mouse   285 NVSTSVEVALQQN-EIM--NTFIDD---WKNLAEEESTFGDKTDTH-------LKEYQSFTDLHN 336

  Fly   294 AVSDMSFC----PSNGDIMAVAYG--------VYSHGKVSKLPRSGWVYVWNIKNPVNPERRYHY 346
            .:..|..|    |:...::.|:..        |.:.|::  |.:...:..|:..:|::|:.....
Mouse   337 TMEKMITCVSWHPTIFGLIVVSVAVRLSYEERVQNSGRL--LLQPSLLLFWSFSDPIHPQLMLES 399

  Fly   347 QVPVVTVEFSPTQPQLLAIGLHNGGVEVRDISGQ-----------------DLPPL--------- 385
            ...:...||.|:.|.::|.|..||.:.:.||:..                 .|.|:         
Mouse   400 PDDIFCFEFCPSDPNIIAGGCINGQIVLWDITAHADRIENIKTGGHRSKKTSLKPMFLLEPDSNK 464

  Fly   386 --------AVSQRLSSPYFEPVTAIKWI-----------YFEG--------------------DV 411
                    |||. :.:.:.:.:|.|.|:           .||.                    |:
Mouse   465 ESMYIRHCAVSS-IENGHRKVITDIHWLPDSFEINRMGSVFENRSGINCQLVTCSADCTICFWDI 528

  Fly   412 GCRNPHITPFLATSQAGAVTKYRLINSPNMLGLEQQRLQRAEGELEGIPIE----------RQPP 466
            ..:.|.:|...|.|.|...|     |:.|.   :|..:::.:.|...||.:          ...|
Mouse   529 RPQKPAVTAAAAASAATTAT-----NNANS---QQSPVEKKKEENIDIPFDVPSTFLHLDLSWKP 585

  Fly   467 AASLLANR------H-PQCLEIVLDP----VQ--SDIYYVLTD----EGTLYKCSTNYPLQHLE- 513
            .:.|..::      | |..|.:..||    :|  |.|:.:|.|    :..:.|.|...|.|:|| 
Mouse   586 LSRLKLSKGDTSLDHCPTKLSLGEDPFLCKIQGTSSIHIILRDKMLSQIKMVKTSEINPYQNLEA 650

  Fly   514 ------------------------------------------------LRQVHDGPAACMEFSPW 530
                                                            |..||||....::.||:
Mouse   651 GIANILKPIEDFCTKFFVGTEEGEVIYTDWKMERDSDTGRLMAKKPVSLYTVHDGAVHTIQRSPF 715

  Fly   531 SPRMYLTCGSDWCIRIWLAGILL-PIVTLQHHLSPVH--CARWSRTHSTIL-VSLSRSTVDIWDL 591
            ...:.||.|. |.:.||...::. |:  ||....|..  ...||.|...:. :......||||||
Mouse   716 FNDIVLTVGG-WNVAIWKEEVMTGPL--LQTCCGPKRYTAGHWSLTRPGVFYIGREDGNVDIWDL 777

  Fly   592 RNSTMKPVSS-----TVIDADIFYTTFKFTHCGRSLAVGNEAGNLLMLSFEDMPFPPHFQYKQLK 651
            ...|.:|..|     |:|   .:...:.|:...:.:||.:..|.|.:|   ::|:          
Mouse   778 LEKTHEPAQSQNICITMI---TYIKPWTFSSKQQFIAVADYYGTLHIL---EIPW---------- 826

  Fly   652 RAIFKALSMQPDLRKQVKSVGYF 674
                 .|| .|.| .:|.||.|:
Mouse   827 -----TLS-HPSL-NEVSSVNYY 842

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG13930NP_647645.1 WD40 repeat 295..344 CDD:293791 10/60 (17%)
WD40 repeat 350..397 CDD:293791 15/80 (19%)
WD40 repeat 400..473 CDD:293791 20/113 (18%)
WD40 442..>629 CDD:441893 56/271 (21%)
WD40 repeat 478..513 CDD:293791 12/44 (27%)
WD40 <518..>593 CDD:475233 24/78 (31%)
WD40 repeat 524..560 CDD:293791 10/36 (28%)
Dnai3NP_766452.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..35
WD 1. /evidence=ECO:0000255 398..438 10/39 (26%)
WD40 479..527 CDD:197651 5/47 (11%)
WD 2. /evidence=ECO:0000255 480..536 7/55 (13%)
WD 3. /evidence=ECO:0000255 702..741 13/41 (32%)
WD 4. /evidence=ECO:0000255 745..785 11/39 (28%)
Blue background indicates that the domain is not in the aligned region.

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