DRSC/TRiP Functional Genomics Resources

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Protein Alignment RabX5 and RAB6C

DIOPT Version :9

Sequence 1:NP_647644.2 Gene:RabX5 / 38209 FlyBaseID:FBgn0035255 Length:277 Species:Drosophila melanogaster
Sequence 2:NP_115520.2 Gene:RAB6C / 84084 HGNCID:16525 Length:254 Species:Homo sapiens


Alignment Length:244 Identity:73/244 - (29%)
Similarity:118/244 - (48%) Gaps:42/244 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    40 LSKERDFGAQVRYYLEAPRKPKFRPCKVIFVGDCSVGKTAIVNRFCYDKFQSNYKATIGVDFELE 104
            :|...|||..:|         ||   |::|:|:.||.||:::.||.||.|.:.|:|.||:||..:
Human     1 MSAGGDFGNPLR---------KF---KLVFLGEQSVAKTSLITRFRYDSFDNTYQAIIGIDFLSK 53

  Fly   105 NFSILGHNYSLEMWDTAGQERFRCIAGAYYRNASVIVVTYDMSKKDSLESAKKWLNSALNYNASK 169
            ...:......|.:||||||||.|.:...|.|:::..||.||::..:|.:...||::.......|.
Human    54 TMYLEDGTIGLRLWDTAGQERLRSLIPRYIRDSAAAVVVYDITNVNSFQQTTKWIDDVRTERGSD 118

  Fly   170 RPLVFLVGTKADLLSKEEFVRMERLAGLAAAELQAEYWSVSARSGFKVTELFQRIAAL-----AF 229
             .::.|||.:.||..|.: |.:|. ....|..|...:....|::|:.|.:||:|:||.     :.
Human   119 -VIITLVGNRTDLADKRQ-VSVEE-GERKAKGLNVTFIETRAKAGYNVKQLFRRVAAALPGMEST 180

  Fly   230 EEAVMQEIRSIK-NKPQEQATQASVKSQTFDLRNFFGSRLSQQKSGCTC 277
            ::...:::..|| .|||||..                     .:.||:|
Human   181 QDGSREDMSDIKLEKPQEQTV---------------------SEGGCSC 208

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RabX5NP_647644.2 P-loop_NTPase 66..230 CDD:304359 56/168 (33%)
RAB 66..225 CDD:197555 54/158 (34%)
RAB6CNP_115520.2 Required for centrosome localization 1..174 63/187 (34%)
Rab6 14..174 CDD:206654 57/165 (35%)
RAB 14..171 CDD:197555 55/162 (34%)
Effector region. /evidence=ECO:0000250 42..50 4/7 (57%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0094
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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