DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RabX5 and rab36

DIOPT Version :9

Sequence 1:	NP_647644.2	Gene:	RabX5 / 38209	FlyBaseID:	FBgn0035255	Length:	277	Species:	Drosophila melanogaster
Sequence 2:	XP_004910645.2	Gene:	rab36 / 733793	XenbaseID:	XB-GENE-490801	Length:	264	Species:	Xenopus tropicalis

Alignment Length:	240	Identity:	100/240 - (41%)
Similarity:	144/240 - (60%)	Gaps:	21/240 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 RLRQNLLLPQPPTVVLHDPRTHLRHLPPAYSAAQTPLSKERDFGAQVRYYLEAPRKPKFRPCKVI 68
            |:..|:..|..|. ..|..:|.       :.|....:.::|:.||           ...:..|.:
Frog    13 RIISNMPKPYTPE-ACHQYQTQ-------FDAEVQTVCQQRNAGA-----------IGLKMSKAV 58

  Fly    69 FVGDCSVGKTAIVNRFCYDKFQSNYKATIGVDFELENFSILGHNYSLEMWDTAGQERFRCIAGAY 133
            .|||..||||:::||||.:.|..:||||||||||:|.|.|||..::.::|||||||:|:|||.||
Frog    59 MVGDLYVGKTSLINRFCKNVFDRDYKATIGVDFEIERFEILGIPFNFQIWDTAGQEKFKCIASAY 123

  Fly   134 YRNASVIVVTYDMSKKDSLESAKKWLNSALNYNASKRPLVFLVGTKADLLSKEEFVRMERLAGLA 198
            ||.|.||:..:|:....:||:.::|:..||..|......:||||||.|.||:.|..|.|:.|...
Frog   124 YRGAQVIITAFDLGDISTLENTRRWVQDALKENEPDTCSIFLVGTKKDTLSEAELERTEQDAVRL 188

  Fly   199 AAELQAEYWSVSARSGFKVTELFQRIAALAFEEAVMQEIRSIKNK 243
            |.:||||||||||::|..|.|.|.|:|:||||:::.:|:.  ||:
Frog   189 AIDLQAEYWSVSAKTGENVKEFFFRVASLAFEQSMKKELE--KNR 231

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RabX5	NP_647644.2	P-loop_NTPase	66..230	CDD:304359	85/163 (52%)
RabX5	NP_647644.2	RAB	66..225	CDD:197555	82/158 (52%)
rab36	XP_004910645.2	P-loop_NTPase	55..220	CDD:422963	85/164 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	184	1.000	Domainoid score	I3351
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3610
Inparanoid	1	1.050	196	1.000	Inparanoid score	I3699
OMA	1	1.010	-	-		QHG48903
OrthoDB	1	1.010	-	-		D1048146at2759
OrthoFinder	1	1.000	-	-		FOG0003705
OrthoInspector	1	1.000	-	-		otm47808
Panther	1	1.100	-	-	O	PTHR47977
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2570
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.080