DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RabX5 and rab34

DIOPT Version :9

Sequence 1:	NP_647644.2	Gene:	RabX5 / 38209	FlyBaseID:	FBgn0035255	Length:	277	Species:	Drosophila melanogaster
Sequence 2:	NP_001006769.1	Gene:	rab34 / 448455	XenbaseID:	XB-GENE-494108	Length:	259	Species:	Xenopus tropicalis

Alignment Length:	263	Identity:	108/263 - (41%)
Similarity:	149/263 - (56%)	Gaps:	24/263 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LRQNLLLPQPPTVVLHDPRTHLRHLPPAYSAAQTPLSKERDFGAQVRYYLEAPRKPKFRPCKVIF 69
            :|::.::.:.|.....:...|.|.   ::.:..|...|::..|. |.|.:.          |||.
Frog     7 VRRDRIVAELPQCFRKEACLHTRE---SFHSKVTSACKQQRTGT-VGYKIS----------KVIV 57

  Fly    70 VGDCSVGKTAIVNRFCYDKFQSNYKATIGVDFELENFSILGHNYSLEMWDTAGQERFRCIAGAYY 134
            |||.|||||.::||||.|.|..|||||||||||:|.|.|||..:||::|||||||||:|||..||
Frog    58 VGDLSVGKTCLINRFCKDTFDKNYKATIGVDFEMERFEILGVPFSLQLWDTAGQERFKCIASTYY 122

  Fly   135 RNASVIVVTYDMSKKDSLESAKKWLNSALNYNASKRPLVFLVGTKADLLSKEEFVRMERLAGLAA 199
            |.|..|::.:|::...|||..|:||..||..|.....|:||||:|.||....::..||:.|...|
Frog   123 RGAQAIIIAFDLTDVSSLEHTKQWLQDALKENDPSSALLFLVGSKKDLSPPAQYALMEKDAIKVA 187

  Fly   200 AELQAEYWSVSARSGFKVTELFQRIAALAFEEAVMQEIRSIK----------NKPQEQATQASVK 254
            .|:||||||||:.:|..|.|.|.|:|:|.||.:|:.|:....          |.......|.|.|
Frog   188 KEMQAEYWSVSSLTGENVKEFFFRVASLTFESSVLAELEKTNARRIGEVVRINSNDRNLYQCSKK 252

  Fly   255 SQT 257
            ::|
Frog   253 NKT 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RabX5	NP_647644.2	P-loop_NTPase	66..230	CDD:304359	90/163 (55%)
RabX5	NP_647644.2	RAB	66..225	CDD:197555	88/158 (56%)
rab34	NP_001006769.1	Rab36_Rab34	53..219	CDD:206693	91/175 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	184	1.000	Domainoid score	I3351
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	196	1.000	Inparanoid score	I3699
OMA	1	1.010	-	-		QHG48903
OrthoDB	1	1.010	-	-		D1048146at2759
OrthoFinder	1	1.000	-	-		FOG0003705
OrthoInspector	1	1.000	-	-		otm47808
Panther	1	1.100	-	-	LDO	PTHR47977
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R8208
SonicParanoid	1	1.000	-	-		X2570
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.110