DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7974 and RGD1305178

DIOPT Version :9

Sequence 1:	NP_001261273.1	Gene:	CG7974 / 38207	FlyBaseID:	FBgn0035254	Length:	294	Species:	Drosophila melanogaster
Sequence 2:	XP_006233977.1	Gene:	RGD1305178 / 311855	RGDID:	1305178	Length:	289	Species:	Rattus norvegicus

Alignment Length:	292	Identity:	144/292 - (49%)
Similarity:	194/292 - (66%)	Gaps:	28/292 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 KNLRQRKNSDEEEKEEQ------LTLDEIKERQRLRQRPNGVSLVGLALGKKIAPEEELAIKDPF 81
            |..|:|:...|.|::||      |.|:|.:|.|.||:||||||...|.:|:|: .||...:.|||
  Rat     6 KTFRRRRADSESEEDEQESEEVRLKLEETREVQNLRKRPNGVSAAALLVGEKV-QEETTLVDDPF 69

  Fly    82 NVKTGGLVNMKQLKS-GKMKEADDAYDVGIGTQFSAETNKRDEDEEMMKYIEQELQKRKGGGTED 145
            .:.|||:|:||:||. ||.|.:::. |:.:||.||||||:||||.:||||||.||:||||
  Rat    70 QMATGGMVDMKKLKERGKDKVSEEE-DLHLGTSFSAETNRRDEDADMMKYIETELKKRKG----- 128

  Fly   146 AAEDDGDVNKYLTPEDAALYALPDHLRQSSSHRSEEMLSNQMLNGIPEVDLGIVAKIRNIEATEE 210
            ..|.:....|....|| .||.||:::|.||:.::|||||||||:|||||||||.|||:||.:||:
  Rat   129 IVEQEEQKAKPKNAED-CLYELPENIRVSSAKKTEEMLSNQMLSGIPEVDLGIDAKIKNIISTED 192

  Fly   211 AKQKLLQDAKN-KKDGPSQFVPTNMAVNFMQHNRFNIED-NSDQRRRKREER-------EGNKSA 266
            ||.:||.:.:| |||..:.|||||||||::|||||..|: |:..||.|.|.:       :..|..
  Rat   193 AKARLLAEQQNKKKDSETSFVPTNMAVNYVQHNRFYHEELNAPIRRNKEEPKARPLRVGDTEKPE 257

  Fly   267 QHQTNPN----GVKRATDDYHYDKFRKQFRRY 294
            ..::.||    ..::|||||||:||:|..|||
  Rat   258 PERSPPNRKRPANEKATDDYHYEKFKKMNRRY 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7974	NP_001261273.1	Hep_59	113..214	CDD:284467	60/100 (60%)
RGD1305178	XP_006233977.1	Hep_59	101..196	CDD:399794	60/100 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342155
Domainoid	1	1.000	110	1.000	Domainoid score	I6189
eggNOG	1	0.900	-	-		E1_KOG3345
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	243	1.000	Inparanoid score	I3227
OMA	1	1.010	-	-		QHG59632
OrthoDB	1	1.010	-	-		D1493869at2759
OrthoFinder	1	1.000	-	-		FOG0006447
OrthoInspector	1	1.000	-	-		oto95733
orthoMCL	1	0.900	-	-		OOG6_103943
Panther	1	1.100	-	-	LDO	PTHR13486
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X5410
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.770