DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17249 and prcc

DIOPT Version :9

Sequence 1:	NP_647638.1	Gene:	CG17249 / 38201	FlyBaseID:	FBgn0035249	Length:	472	Species:	Drosophila melanogaster
Sequence 2:	NP_001107967.1	Gene:	prcc / 100038213	XenbaseID:	XB-GENE-488406	Length:	514	Species:	Xenopus tropicalis

Alignment Length:	545	Identity:	134/545 - (24%)
Similarity:	207/545 - (37%)	Gaps:	158/545 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 SVPQVEVIKPQA-----KPSTPSEAYLARESTSGHISDEDDDYVPQEVSLQELKPPNGRLLLALP 80
            |:|..:..:||:     .||:|:.|.:.:..             |...:...|.||.|...|..|
Frog    35 SLPPPQGARPQSGTGMTLPSSPNTAGMNQPP-------------PPGTTGINLPPPQGGSGLNFP 86

  Fly    81 KP--KVTAPAKDLENEDVDNQVTSAF----------ANLPMPR---TAAKGKAIVEEKDDEFLHK 130
            .|  .:..|..         .::|..          .|:|.|:   |:|.|          ..|:
Frog    87 PPGHGINLPPP---------HISSGLKLPPPQGGQGLNIPPPQLSPTSASG----------LDHR 132

  Fly   131 KALPVEIEKPP-----PPP-------VKGK-----VKISIPSLRDFSDVDQEKADRAKNKVDKPN 178
            ..||     ||     |||       .|.|     |||::|.|.. :..|.|:.:....|.....
Frog   133 MPLP-----PPGYNVLPPPSIENVGNPKPKKRTEPVKITVPELHT-AGSDSEEDEPTTKKAVVQG 191

  Fly   179 VPKGSGLLSLLPQAKSERNFSKNSSSAVAYPSASTTLASSLSNNPAQPRAAPAFVPDTVKQRRAA 243
            ..:|.||.:||||.|   |.|.:.|.....|......||:.:::...||:.|...|....:
Frog   192 SREGYGLSALLPQPK---NASGSDSKRQLLPYNFLKKASNPASDLKHPRSTPLTKPKLSSK---- 249

  Fly   244 HNTEGVDGPKAGHKKNPETKDALKSTKSKPISKPTSLVNASDSEDDDED-GTGDFFSLNSEQKLP 307
                    |:..|..:|   .|:|:.......:.|..:...:.||.||| ..|:||||:..::.|
Frog   250 --------PEVSHTPSP---SAIKAAAKNAALQVTKQITQEEDEDSDEDLQHGNFFSLSDTKETP 303

  Fly   308 -------------------------EVSSNEISA-LVAKRAAKMVE------------ASSKYLE 334
                                     |:..:..:| |..|.||...:            :|.:|.:
Frog   304 AMMRESYPYPAPTVDETAPPGVEPVELQDDAANAPLDFKTAAGSSDNHQWPASNAEAYSSQQYSQ 368

  Fly   335 --EVAEKEA---------------AEAEAARLQEEQSQIAQKRYHEQQLNAEAMDALVGKNAKRR 382
              |.|:..|               :::.:|.|:|..:..|     :..::.||...|.||    |
Frog   369 YPEYADTSASGYYQDYYSSDYYQESDSSSAALKETAAAAA-----DSFMDDEAFKRLQGK----R 424

  Fly   383 RKEAKEMQVIDISGSQVLPDREEWMRSALASSTTFQPTGVLTDEEPVAGTRRKHQITYLAHKAKA 447
            .:..:|:..:||.|...|...::|:..:|....|.:.......|:|....|||||||||.|:||.
Frog   425 NRGREEINFVDIKGDDQLSGNQQWLTKSLTEEKTMKSFSKRKGEQPTGQQRRKHQITYLIHQAKE 489

  Fly   448 NEAELQAMWSANRQTRRATQSKYGF 472
            .|.||:..||.|:.:||.||:||||
Frog   490 RELELKNSWSDNKMSRRQTQAKYGF 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17249	NP_647638.1	PRCC	<371..472	CDD:287255	38/100 (38%)
prcc	NP_001107967.1	PRCC	393..514	CDD:287255	44/129 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	85	1.000	Domainoid score	I8106
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1430154at2759
OrthoFinder	1	1.000	-	-		FOG0007347
OrthoInspector	1	1.000	-	-		oto103549
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3708
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.040