Protein Alignment alphaCOP and AT2G21390

DIOPT Version :10

• Sequence 1: NP_477395.1
• Gene: alphaCOP / 38199
• FlyBaseID: FBgn0025725
• Length: 1234
• Species: Drosophila melanogaster
• Sequence 2: NP_179734.1
• Gene: AT2G21390 / 816678
• AraportID: AT2G21390
• Length: 1218
• Species: Arabidopsis thaliana
• Alignment Length: 1261
• Identity: 675/1261 - (53%)
• Similarity: 883/1261 - (70%)
• Gaps: 70/1261 - (5%)

  Fly     1 MLTNFESKSARVKGLSFHPKRPWILVSLHSGVIQLWDYRMHTLLEKFDEHDGPVRGVAFHQQMPL 65
            |||.||:||.|||||||||||||||.||||||||||||||.||:::||||:||||||.||...||
plant     1 MLTKFETKSNRVKGLSFHPKRPWILASLHSGVIQLWDYRMGTLIDRFDEHEGPVRGVHFHNSQPL 65

  Fly    66 FVSGGDDYKIKVWNYKQRRCIFTLLAHLDYVRTVAFHHEYPWILSASDDQTIRIWNWQSRNCICV 130
            ||||||||||||||||..||:||||.||||:|||.||||.|||:||||||||||||||||.||.|
plant    66 FVSGGDDYKIKVWNYKTHRCLFTLLGHLDYIRTVQFHHENPWIVSASDDQTIRIWNWQSRTCISV 130

  Fly   131 LTGHNHYVMCAQFHPTEDQIVSASLDQTVRVWDISGLRKKNVAPGPGGLDDHLKGHPGATDLFGQ 195
            |||||||||||.|||.||.:||||||||||||||..|:||:.:|.    ||.::.....:||||.
plant   131 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALKKKSASPA----DDLMRFSQMNSDLFGG 191

  Fly   196 ADAVVKHVLEGHDRGVNWASFHPTLPLIVSGADDRLVKLWRMNEYKAWEVDTCRGHYNNVSSVLF 260
            .||:||:||||||||||||||||||||||||||||.||||||||.|||||||.|||.||||||:|
plant   192 VDAIVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNETKAWEVDTLRGHMNNVSSVMF 256

  Fly   261 HPRQDLILSNGEDRSIRVWDMTKRQCLFTFRRDNERFWILTAHPTLNLFAAGHDGGMVVFKLERE 325
            |.:||:|:||.||:||||||.|||..:.||||:::|||||..||.:||.|||||.||:|||||||
plant   257 HAKQDIIVSNSEDKSIRVWDATKRTGIQTFRREHDRFWILAVHPEINLLAAGHDNGMIVFKLERE 321

  Fly   326 RPAYAVHGNILYYVKERFLRKLDFTTTKDTVVMQL-RPG-----KSPVYSMSYNPALNAVLICTR 384
            |||:|:.|:.|:|.|:||||..:::|.||:.|:.: |||     :|| .::||:|..||||||
plant   322 RPAFALSGDSLFYAKDRFLRYYEYSTQKDSQVIPIRRPGTPSLNQSP-RTLSYSPTENAVLIC-- 383

  Fly   385 TNNLENSTYDLCQIPKDTESQSE--SDSKRSSGITAIWVARNRFAVLDRN-QQLVIKNFKNEVTK 446
             ::|:..:|:|..||||:..:|:  .|:||.:|.:|:::||||||||::: .|:::||.||||.|
plant   384 -SDLDGGSYELYIIPKDSVGRSDVVQDAKRGTGGSAVFIARNRFAVLEKSTSQVLVKNLKNEVVK 447

  Fly   447 K--LPTFCEEIFYAGTGMLLIRDPEFVTLYEVQRLVSVGSIKLAKCRYVVWSPDMSLVALLCKHS 509
            |  ||...:.|||||||.||.|..:.|.::::|:.:.:|.::....||||||.||..||||.||:
plant   448 KSSLPIPTDAIFYAGTGNLLCRSEDKVVIFDLQQRLVLGELQTPFVRYVVWSNDMESVALLSKHT 512

  Fly   510 VTICDRRLQYLCTVQENCRVKSGAWDESGVFIYTTSNHIKYAITNGDHGIIRTLDLPIYLTRVKG 574
            :.|..::|...||:.|..||||||||::|||||||.|||||.:.|||.|||||||:|||:|:|.|
plant   513 IIIASKKLVLQCTLHETIRVKSGAWDDNGVFIYTTLNHIKYCLPNGDSGIIRTLDVPIYITKVSG 577

  Fly   575 NQVFCLDRECRTRVLHIDPTEYKFKLALIQRKYDEVLHMVRNARLVGQSIIAYLQQKGYPEVALH 639
            |.:|||||:.:.|.:.|:.|||.|||||:::|||.|:.|::|::|.||::||||||||:||||||
plant   578 NTIFCLDRDGKNRAITINATEYIFKLALLRKKYDHVMSMIKNSQLCGQAMIAYLQQKGFPEVALH 642

  Fly   640 FVKDEKTRFGLALECGNIEIALEAAKALDDKDCWDRLGQSALLQGNHQVVEMCYQRTKNFDKLSF 704
            ||:||:.||.||||.|||.:|:.:|..:::||.|.|||..||.|||.::||..||:||||::|||
plant   643 FVEDERIRFNLALESGNISVAVASATEINEKDHWYRLGVEALRQGNSRIVEFAYQQTKNFERLSF 707

  Fly   705 LYLITGNLEKLKKMNKIAEIRKDVSAQYQGALLLGDVKERVNILKNCGQLSLAYLTAATHGFDEL 769
            ||||||||:||.|:.||||::.:|..|:..||.||||||||.||:|.|.|.|||:||:.||..::
plant   708 LYLITGNLDKLSKLMKIAEVKNNVMGQFHNALYLGDVKERVKILENAGHLPLAYITASVHGLTDI 772

  Fly   770 TESLGESITSQGNSLPEVNPNAQLLQPPVPIQQLETNWPLLSVSKGFFEGAMVTRAGSSATARQA 834
            .|.|...:.....|||| .....||.||.|| ....:||||.|.||.|||.:.
plant   773 AERLAIELGDNVPSLPE-GKTPSLLMPPSPI-MCGGDWPLLRVMKGIFEGGLE------------ 823

  Fly   835 LNINADAALLDEHNGGGDG-WGADADLGLDEDGDDEMHDA-LSNDGDGGAGGE----EGAGWDVG 893
               :|:...:||.....:| ||.    |||:...|.|.:. :....||...||    |..||.:
plant   824 ---SANRGAVDEEEEDVEGDWGE----GLDKFDVDGMENTDIEAILDGAEAGEEEDDEEGGWGL- 880

  Fly   894 DDDLVVPEELASKIKASA-LDSNYYAAPNKGLSPAQQWANNSPLVLDHVKAGSFETAFRLLHDQL 957
              ||.:|.||.:. |||| ..|:.:..|.:|:..:|.|:..|.|..:...||||:||.||||.||
plant   881 --DLDLPPELDTP-KASANARSSTFVTPPQGMPVSQIWSQKSSLAAEQAAAGSFDTAMRLLHRQL 942

  Fly   958 GVVNFQPFKTLFLQNYACSRTSYTANPNLQSLSGYPL------RNYSETNIKLQR--PAVGIKLN 1014
            |:.||.|.|::||..::.|. ||     |::.|..|:      |.:||::....|  ||:....:
plant   943 GIKNFAPLKSMFLDLFSGSH-SY-----LRAFSSSPVVPLAIERGWSESSSPNVRGPPALVFDFS 1001

  Fly  1015 DLVARLQAGYQLTTSGKFSEAVEKFHSILISIPLLVVDTKLDAAEAQQLLRICAEYIVGLKMETV 1079
            .|.|:|::||:.||:||.|||:..|.|||.:|||:||:::.:..|.::|:.|..||::||::|..
plant  1002 QLEAKLKSGYKATTAGKLSEALRVFLSILQTIPLVVVESRREVDEVKELVIIVKEYVLGLQLELK 1066

  Fly  1080 RKGMPKSTLEEQKRLCEMAAYFTHCKLQPVHQILTLRTALNMFFKLKNYKTAASFARRLLELAPR 1144
            |:.|....:.:|    |:||||||||||..|..|...:|:.:.:|.||..|||.|||.||:..|.
plant  1067 RREMKDDPVRQQ----ELAAYFTHCKLQTPHLRLAYFSAMTVCYKSKNMATAAHFARSLLDTNPT 1127

  Fly  1145 -PDVAQQVRKILQACEVNPVDEHQLQYEEFNPFTICGISWKPLYRGKPEVTCPFCSSSFDPQFKG 1208
             ...|:..|:::||.|.|..|...|.|:..|||.|||.::.|:|:|:.:|.||:|::.|.|..:|
plant  1128 IESQARTARQVMQAAERNMTDATTLNYDFRNPFVICGSTYVPIYKGQKDVACPYCTARFVPSQEG 1192

  Fly  1209 NLCTVCEVSQIGKDSIGLRISNLQFR 1234
            |:|:||:::.||.|:.||..|..|.|
plant  1193 NICSVCDLAVIGADASGLLCSASQVR 1218

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaCOP	NP_477395.1	WD40	5..321	CDD:238121	239/315 (76%)
		WD40 repeat	15..49	CDD:293791	28/33 (85%)
		WD40 repeat	57..91	CDD:293791	26/33 (79%)
		WD40 repeat	97..133	CDD:293791	30/35 (86%)
		WD40 repeat	138..205	CDD:293791	38/66 (58%)
		WD40 repeat	212..249	CDD:293791	34/36 (94%)
		WD40 repeat	255..291	CDD:293791	23/35 (66%)
		WD40 repeat	299..352	CDD:293791	32/52 (62%)
		Coatomer_WDAD_alpha	327..773	CDD:438573	245/456 (54%)
		WD40 repeat	327..340	CDD:438573	6/12 (50%)
		WD40 repeat	365..414	CDD:438573	22/50 (44%)
		WD40 repeat	417..439	CDD:438573	10/22 (45%)
		WD40 repeat	458..487	CDD:438573	10/28 (36%)
		WD40 repeat	490..522	CDD:438573	16/31 (52%)
		WD40 repeat	538..564	CDD:438573	20/25 (80%)
		WD40 repeat	566..591	CDD:438573	13/24 (54%)
		COPI_C	815..1228	CDD:462050	161/428 (38%)
AT2G21390	NP_179734.1	WD40	9..317	CDD:238121	236/311 (76%)
		WD40 repeat	15..49	CDD:293791	28/33 (85%)
		WD40 repeat	55..91	CDD:293791	28/35 (80%)
		WD40 repeat	96..132	CDD:293791	29/35 (83%)
		WD40 repeat	139..201	CDD:293791	37/65 (57%)
		WD40 repeat	207..245	CDD:293791	35/37 (95%)
		WD40 repeat	251..288	CDD:293791	24/36 (67%)
		WD40 repeat	295..316	CDD:293791	13/20 (65%)
		Coatomer_WDAD_alpha	323..776	CDD:438573	245/456 (54%)
		WD40 repeat	323..336	CDD:438573	6/12 (50%)
		WD40 repeat	366..414	CDD:438573	22/51 (43%)
		WD40 repeat	417..440	CDD:438573	10/22 (45%)
		WD40 repeat	461..490	CDD:438573	10/28 (36%)
		WD40 repeat	493..525	CDD:438573	16/31 (52%)
		WD40 repeat	541..567	CDD:438573	20/25 (80%)
		WD40 repeat	569..594	CDD:438573	13/24 (54%)
		COPI_C	816..1212	CDD:462050	161/428 (38%)