Protein Alignment Mettl2 and ABP140

DIOPT Version :10

• Sequence 1: NP_647636.3
• Gene: Mettl2 / 38197
• FlyBaseID: FBgn0035247
• Length: 325
• Species: Drosophila melanogaster
• Sequence 2: NP_014882.4
• Gene: ABP140 / 854414
• SGDID: S000005765
• Length: 628
• Species: Saccharomyces cerevisiae
• Alignment Length: 295
• Identity: 125/295 - (42%)
• Similarity: 179/295 - (60%)
• Gaps: 4/295 - (1%)

  Fly    32 RKKPSGAGSRVLTDAREVFEFNAWDHVQWDEEQELAAKAAVAKNSTSKMEAEQKERFQTDAPKFW 96
            |..|...|.|.||:..:|::.||||:|:|.|||...|:..:.:.....:....|:.:..:..::|
Yeast   335 RDLPFEFGKRNLTEESDVWDHNAWDNVEWGEEQVQQAEEKIKEQFKHPVPEFDKKLYNENPARYW 399

  Fly    97 DSFYGIHDNRFFKDRHWLFTEFPELAPLAADSAVLQPRSIFELGCGVGNTILPLLQYSSEPQLKV 161
            |.||..:...|||||.||..|||.|  .|:.....:|.:|||:|||.|||..|:|:.:....|::
Yeast   400 DIFYKNNKENFFKDRKWLQIEFPIL--YASTRKDAEPVTIFEIGCGAGNTFFPILKDNENENLRI 462

  Fly   162 FGCDFSARAIEILRSQRQFDEKRCEVFVMDATLDHWQVP--FEENSQDIIVMIFVLSAIEPKKMQ 224
            ...||:.||:|::::..||:.|.....|.|.......:|  .|.:|.||.|||||.||:.|.:..
Yeast   463 IAADFAPRAVELVKNSEQFNPKYGHATVWDLANPDGNLPDGVEPHSVDIAVMIFVFSALAPNQWD 527

  Fly   225 RVLDNCYRYLRPGGLLLFRDYGRYDLAQLRFKSGKCMEDNFYVRGDGTMVYFFTEEELRGMMTQA 289
            :.:||.::.|:|||.::|||||.|||.|:|||..:.:|:|||||||||.||||:||:||.:.|:.
Yeast   528 QAMDNLHKILKPGGKIIFRDYGAYDLTQVRFKKNRILEENFYVRGDGTRVYFFSEEKLREIFTKK 592

  Fly   290 GLQEEQLIVDRRLQVNRCRGLKMYRVWIQTKFRKP 324
            ...|.::..||||.|||.|.|||||.|:|..|..|
Yeast   593 YFLENKIGTDRRLLVNRKRQLKMYRCWVQAVFDVP 627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mettl2	NP_647636.3	Methyltransf_25	136..238	CDD:463945	39/103 (38%)
		COG4627	187..308	CDD:443666	60/122 (49%)
ABP140	NP_014882.4	2A1904	<53..>247	CDD:273344
		Methyltransf_12	438..543	CDD:400515	40/104 (38%)