Protein Alignment Mettl2 and mettl6

DIOPT Version :10

• Sequence 1: NP_647636.3
• Gene: Mettl2 / 38197
• FlyBaseID: FBgn0035247
• Length: 325
• Species: Drosophila melanogaster
• Sequence 2: NP_956497.2
• Gene: mettl6 / 791999
• ZFINID: ZDB-GENE-040426-926
• Length: 286
• Species: Danio rerio
• Alignment Length: 304
• Identity: 117/304 - (38%)
• Similarity: 162/304 - (53%)
• Gaps: 35/304 - (11%)

  Fly    36 SGAGSRVLTDAREVFEFNAWDHVQWDEEQELAAKAAVAKNSTSKMEAE------------QKERF 88
            |.:|..|..:.|.||.               .....|.:.|.:..|.|            ::::.
Zfish     2 SASGESVSLEYRPVFP---------------PQSTVVRERSLTPEEMEKLGNDRVLVSDFKQQKL 51

  Fly    89 QTDAPKFWDSFYGIHDNRFFKDRHWLFTEFPELAPLAADSAVLQPRSIFELGCGVGNTILPLLQY 153
            :|||.|.||.||..:...|||||||...||.||........  |...:.|.||||||.|.|||:
Zfish    52 ETDAQKNWDLFYKRNTTNFFKDRHWTTREFDELKNCRESEG--QKLVLLEAGCGVGNCIFPLLE- 113

  Fly   154 SSEPQLKVFGCDFSARAIEILRSQRQFDEKRCEVFVMDATLDHWQVPFEENSQDIIVMIFVLSAI 218
             .:..:.::.||||.||:|.::....:..:||..|..|.|.|..|...:..:.|:..:|||||||
Zfish   114 -EDLNIFIYACDFSPRAVEFVKKNALYCTERCLAFQCDLTKDDLQANIQVGTVDVATLIFVLSAI 177

  Fly   219 EPKKMQRVLDNCYRYLRPGGLLLFRDYGRYDLAQLRFKSGKCMEDNFYVRGDGTMVYFFTEEELR 283
            .|.|||:.|:..|:.|||||::.|||||.||.|.||||||..:.:|||||.|||..:||:.|.|.
Zfish   178 HPDKMQKSLEQIYKVLRPGGIVFFRDYGLYDHAMLRFKSGNKLGENFYVRQDGTRSFFFSREYLA 242

  Fly   284 GMMTQAGLQEEQLIVDRRLQ--VNRCRGLKMYRVWIQTKFRKPL 325
            |:...||.  |.|:.:..|:  ||:..||.:.||::|:|||:|:
Zfish   243 GLFQNAGF--ETLVNEYVLRETVNKKEGLCVPRVFLQSKFRRPV 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mettl2	NP_647636.3	Methyltransf_25	136..238	CDD:463945	42/101 (42%)
		COG4627	187..308	CDD:443666	58/122 (48%)
mettl6	NP_956497.2	Methyltransf_12	98..199	CDD:400515	44/102 (43%)