Protein Alignment Mettl2 and Mettl2

DIOPT Version :10

• Sequence 1: NP_647636.3
• Gene: Mettl2 / 38197
• FlyBaseID: FBgn0035247
• Length: 325
• Species: Drosophila melanogaster
• Sequence 2: NP_001102309.1
• Gene: Mettl2 / 363687
• RGDID: 1310240
• Length: 385
• Species: Rattus norvegicus
• Alignment Length: 367
• Identity: 163/367 - (44%)
• Similarity: 216/367 - (58%)
• Gaps: 65/367 - (17%)

  Fly    23 SKSWEHTRQRKKPSGAGSRVLTDAREVFEFNAWDHVQWDEEQELAAKAAVAKNSTSKMEAEQKER 87
            |:....|..||:|. .|:|.|:|...||..||||:|:|.|||..||:..|.:||:..:..|::..
  Rat     6 SEGVPETEDRKRPQ-FGNRFLSDPARVFHHNAWDNVKWSEEQAAAAERKVQENSSQLVCPEKQAD 69

  Fly    88 FQTDAPKFWDSFYGIHDNRFFKDRHWLFTEFPELAPL----------AADSAVLQPRS------- 135
            ::.:|.|:||.||.:|:|.|||||||||||||||||.          ...:.|.:|||
  Rat    70 YEVNAHKYWDDFYKVHENGFFKDRHWLFTEFPELAPSHDHLVNLHLEKQKNEVSKPRSSEDGPGL 134

  Fly   136 -----------------------------------------------IFELGCGVGNTILPLLQY 153
                                                           |.|:|||||||:.|:||.
  Rat   135 AAEQHKRPCTSHGCETRVPPVEEPVTQKLTHLEICADDFPGSSATYRILEVGCGVGNTVFPILQT 199

  Fly   154 SSEPQLKVFGCDFSARAIEILRSQRQFDEKRCEVFVMDATLDHWQVPFEENSQDIIVMIFVLSAI 218
            ::.|.|.|:.|||||.|||::::..::|..||..||.|...:....|..::|.|:||:|||||||
  Rat   200 NNNPDLFVYCCDFSATAIELVKTNSEYDPSRCFAFVHDLCDEDQSYPMPKDSLDVIVLIFVLSAI 264

  Fly   219 EPKKMQRVLDNCYRYLRPGGLLLFRDYGRYDLAQLRFKSGKCMEDNFYVRGDGTMVYFFTEEELR 283
            .|.|||:.:....|.|:|||::|.|||||||:||||||.|:|:..|||||||||.|||||::||.
  Rat   265 VPDKMQKAISKLSRLLKPGGVMLLRDYGRYDMAQLRFKKGQCLSGNFYVRGDGTRVYFFTQDELD 329

  Fly   284 GMMTQAGLQEEQLIVDRRLQVNRCRGLKMYRVWIQTKFRKPL 325
            .:.|.|||::.|.:|||||||||.:.|.|||||||.|:.|||
  Rat   330 TLFTAAGLEKVQNVVDRRLQVNRGKQLTMYRVWIQCKYSKPL 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mettl2	NP_647636.3	Methyltransf_25	136..238	CDD:463945	48/101 (48%)
		COG4627	187..308	CDD:443666	70/120 (58%)
Mettl2	NP_001102309.1	Methyltransf_25	182..284	CDD:463945	60/101 (59%)