Protein Alignment Mettl2 and trm141

DIOPT Version :10

• Sequence 1: NP_647636.3
• Gene: Mettl2 / 38197
• FlyBaseID: FBgn0035247
• Length: 325
• Species: Drosophila melanogaster
• Sequence 2: NP_595764.1
• Gene: trm141 / 2541032
• PomBaseID: SPBC3H7.11
• Length: 248
• Species: Schizosaccharomyces pombe
• Alignment Length: 255
• Identity: 95/255 - (37%)
• Similarity: 135/255 - (52%)
• Gaps: 21/255 - (8%)

  Fly    78 SKMEAEQKERFQTDAPKFWDSFYGIHDNRFFKDRHWLFTEF------PELAPLAADSAVLQPRSI 136
            ||:.....|:::.::.|.||.||..::.|||||||||..||      |:..||          :|
pombe     5 SKLSDFWVEKYKKESKKSWDKFYKRNETRFFKDRHWLDREFDCYFGLPDKLPL----------TI 59

  Fly   137 FELGCGVGNTILPLLQYSSEPQLKVFGCDFSARAIEILRSQRQFDEKRCEVFVMDATLDHWQVPF 201
            .|:||||||.:.|||:.  :|.||::.||||.|||:.::....::|.|...||.|.|.|......
pombe    60 LEVGCGVGNLVYPLLEV--QPNLKIYCCDFSPRAIDFVKKHSCYNENRVFPFVNDITEDSLLEVL 122

  Fly   202 EENSQDIIVMIFVLSAIEPKKMQRVLDNCYRYLRPGGLLLFRDYGRYDLAQLRFKSG---KCMED 263
            .....|.:..|||||||..:|..|.:.|....::|||.|:||||...|.||.:|.:.   ..:::
pombe   123 GSACIDTLTAIFVLSAIPREKQLRSIKNLASVIKPGGHLVFRDYCDGDFAQEKFMTSGDPSMIDE 187

  Fly   264 NFYVRGDGTMVYFFTEEELRGMMTQAGLQEEQLIVDRRLQVNRCRGLKMYRVWIQTKFRK 323
            ..:||.|||:..||.||::...|..||.....|....|...||.|.|.|.|.::|..::|
pombe   188 QTFVRQDGTLSLFFREEDIAEWMKSAGFGLVTLDRVNRTVDNRKRNLNMKRTFLQGVWKK 247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mettl2	NP_647636.3	Methyltransf_25	136..238	CDD:463945	40/101 (40%)
		COG4627	187..308	CDD:443666	44/123 (36%)
trm141	NP_595764.1	Methyltransf_12	60..161	CDD:400515	41/102 (40%)