Protein Alignment Mettl2 and trm140

DIOPT Version :10

• Sequence 1: NP_647636.3
• Gene: Mettl2 / 38197
• FlyBaseID: FBgn0035247
• Length: 325
• Species: Drosophila melanogaster
• Sequence 2: NP_596587.2
• Gene: trm140 / 2540321
• PomBaseID: SPBC21C3.07C
• Length: 307
• Species: Schizosaccharomyces pombe
• Alignment Length: 310
• Identity: 127/310 - (40%)
• Similarity: 180/310 - (58%)
• Gaps: 28/310 - (9%)

  Fly    31 QRKKPSGA-----------GSRVLTDAREVFEFNAWDHVQWDEEQELAAKAAVAKNSTSKMEAEQ 84
            ::||.|..           |.|:||:..:|||.||||||:||:|....||..:.:...  ....:
pombe     9 EKKKTSSVREATFSINESFGGRLLTEEEDVFEQNAWDHVEWDDEHLALAKKCIEEQKL--YPVTE 71

  Fly    85 KERFQTDAPKFWDSFYGIHDNRFFKDRHWLFTEFPELAPLAADSAVLQPRSIFELGCGVGNTILP 149
            |:.:.|...::||.|||.::.:||.:|.|:..|||||..|..:.|  ..:||.|:|||.||||.|
pombe    72 KDAYMTHPERYWDQFYGKNEGKFFMNRRWIAQEFPELLDLLKEDA--GEKSILEIGCGAGNTIWP 134

  Fly   150 LLQYSSEPQLKVFGCDFSARAIEILRSQRQFDEKRCEVFVMDATLDHWQVPFEENSQDIIVMIFV 214
            :|:.:....||:|..|:|.:||::::....:|.|.|...|.|..........||.|.|.|.:||.
pombe   135 ILKENKNSNLKIFAVDYSEKAIDVVKQNPLYDAKFCSASVWDLAGSDLLRSIEEASIDAITLIFC 199

  Fly   215 LSAIEPKKMQRVLDNCYRYLRPGGLLLFRDYGRYDLAQLRFKSGKCMEDNFYVRGDGTMVYFFTE 279
            .||:.|.:.|:.::|.||.|:||||:|||||||.||.|||.|..:.:.:|||:|||||.||:.|.
pombe   200 FSALSPDQWQQAIENLYRLLKPGGLILFRDYGRLDLTQLRAKKNRILSENFYIRGDGTRVYYMTN 264

  Fly   280 EELRGM------MTQAGLQEEQLIVDRRLQVNRCRGLKMYRVWIQTKFRK 323
            |||..:      :.|.|       ||:||.|||.:.:||||.|:|.||:|
pombe   265 EELVDVFGKNFKIIQNG-------VDKRLIVNRKKRVKMYRCWLQAKFQK 307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mettl2	NP_647636.3	Methyltransf_25	136..238	CDD:463945	39/101 (39%)
		COG4627	187..308	CDD:443666	57/126 (45%)
trm140	NP_596587.2	UbiE	107..240	CDD:441828	58/134 (43%)