Protein Alignment Mettl2 and Mettl2

DIOPT Version :10

• Sequence 1: NP_647636.3
• Gene: Mettl2 / 38197
• FlyBaseID: FBgn0035247
• Length: 325
• Species: Drosophila melanogaster
• Sequence 2: XP_061501457.1
• Gene: Mettl2 / 1276647
• VectorBaseID: AGAMI1_010650
• Length: 362
• Species: Anopheles gambiae
• Alignment Length: 357
• Identity: 192/357 - (53%)
• Similarity: 245/357 - (68%)
• Gaps: 38/357 - (10%)

  Fly     6 SSTMLGKY-----------GWQILRRLASK---SWEHTRQRKKPSGAGSRVLTDAREVFEFNAWD 56
            |||.||:.           ....::|..|:   .:|:||.||||:|.|:|.|.|..:|:.||.||
Mosquito     3 SSTTLGRLLLSSVILARHRAACAVQRAGSRHYCDYEYTRYRKKPAGGGTRFLRDPAQVYRFNTWD 67

  Fly    57 HVQWDEEQELAAKAAVAKNSTSKMEAEQKERFQTDAPKFWDSFYGIHDNRFFKDRHWLFTEFPEL 121
            :||||||||.||...|.|||:.|:...:..|.:|:|.:.||.|||||.|||||||||||||||||
Mosquito    68 NVQWDEEQENAALEGVKKNSSVKLSDAEVTRLETEADQNWDRFYGIHQNRFFKDRHWLFTEFPEL 132

  Fly   122 APLAADSAV------------------------LQPRSIFELGCGVGNTILPLLQYSSEPQLKVF 162
            ||....:.|                        .:.|:|||:|||||||:.|:|:||.|..|.::
Mosquito   133 APAKGPNTVPERVLPDGEPVKRAEEVSQESDGQQRRRTIFEIGCGVGNTVFPILKYSEEKNLMIY 197

  Fly   163 GCDFSARAIEILRSQRQFDEKRCEVFVMDATLDHWQVPFEENSQDIIVMIFVLSAIEPKKMQRVL 227
            ..|||.:||:|:....::|..||:.||:|||.|.|.|||.|||.||:|:|||||||:|::||.|:
Mosquito   198 ASDFSRQAIDIMCQSPEYDTNRCKAFVLDATADRWDVPFAENSIDIVVLIFVLSAIDPERMQHVV 262

  Fly   228 DNCYRYLRPGGLLLFRDYGRYDLAQLRFKSGKCMEDNFYVRGDGTMVYFFTEEELRGMMTQAGLQ 292
            :...|||:|||:::.||||||||||||||.|||::||||||||||:|||||:|:||.:.|.|||.
Mosquito   263 NQIARYLKPGGMVMLRDYGRYDLAQLRFKPGKCLKDNFYVRGDGTLVYFFTQEDLRTLFTSAGLV 327

  Fly   293 EEQLIVDRRLQVNRCRGLKMYRVWIQTKFRKP 324
            |||.||||||||||.:.:||||||:|.|||||
Mosquito   328 EEQNIVDRRLQVNRGKMVKMYRVWVQVKFRKP 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mettl2	NP_647636.3	Methyltransf_25	136..238	CDD:463945	56/101 (55%)
		COG4627	187..308	CDD:443666	85/120 (71%)
Mettl2	XP_061501457.1	None