Protein Alignment GC and Ggcx

DIOPT Version :9

• Sequence 1: NP_001163323.1
• Gene: GC / 38194
• FlyBaseID: FBgn0035245
• Length: 672
• Species: Drosophila melanogaster
• Sequence 2: NP_062776.1
• Gene: Ggcx / 56316
• MGIID: 1927655
• Length: 757
• Species: Mus musculus
• Alignment Length: 630
• Identity: 266/630 - (42%)
• Similarity: 372/630 - (59%)
• Gaps: 45/630 - (7%)

  Fly    37 HKSAKKSFLPQNAFFRDCLGHDLSNFTSLTNFTSWLNRPVDGAALGIFRLLYGAAMLIDIAEERG 101
            :|||:.|.|.|.:.....||.:.::.:|..:..:.||:|.|.|.|.:||.|:...||:||.:|||
Mouse    20 NKSAQTSGLKQGSRMEKILGFEWTDLSSWQSVVTLLNKPTDPANLAVFRFLFAFLMLLDIPQERG 84

  Fly   102 GGQLDVRFQEPLH-CHFPLFNGMRALDYPLMGCVYLCMWLGAWGIMLGYRFRTSCLAFLIPYWYI 165
            ...||.::.:.|. |.|||.:.:|.|....|..||..|:|||.|:|||..:|.||:.||:||||:
Mouse    85 LSSLDRKYLDGLDVCRFPLLDALRPLPLDWMYLVYTIMFLGALGMMLGLCYRLSCVLFLLPYWYV 149

  Fly   166 FLLDKPTWNNHSYLFGLVGTLLLFTQAESYCSLDRWLNPRKSHC-IPYWNYFLIKFQFFILYMYA 229
            |||||.:|||||||:||:...|.|..|..|.|:|..||.||.:. :|.|||.:::.|.||:|..|
Mouse   150 FLLDKTSWNNHSYLYGLLAFQLTFMDANHYWSVDGLLNARKKNAHVPLWNYTVLRGQIFIVYFIA 214

  Fly   230 GLKKFSLEWLSGYAMSNLSYHWVFAPFRQVIDPELIDLLIVHWFTAFFDVSIAFFMTLEKTRLLV 294
            |:||...:|:.||:|.:||.||:|:||:.|:..||..||:|||.....|:|..|.:..:.:|.:.
Mouse   215 GVKKLDADWVGGYSMEHLSRHWLFSPFKLVLSEELTSLLVVHWCGLLLDLSAGFLLFFDASRPVG 279

  Fly   295 TPFMLSFHLMNSRLFVIGMFPWVCLAEVPLFFSFDWPRRLGNW--SKIQDVHPKD--PEEELS-- 353
            ..|:..||.|||:||.|||||:|.||..|||.|.:|||:|...  .::|::.|..  |....|
Mouse   280 LFFVSYFHCMNSQLFSIGMFPYVMLASSPLFCSAEWPRKLVARCPKRLQELLPTKAAPRPSASCV 344

  Fly   354 ----------KPGILARLRTGLILAYCGLQLFLPYSHFITKGYNNWTNGLYGYSWDMMVHSYDTL 408
                      |||:..:|.....|.|...|||||||||:|:||||||||||||||||||||....
Mouse   345 YKRSRGKAGPKPGLRHQLGAIFTLLYLLEQLFLPYSHFLTQGYNNWTNGLYGYSWDMMVHSRSHQ 409

  Fly   409 QTSIQVVDNESRQVHNLNPYAFTEYDRWTKYADMAVQYARCI-----EENLQEKQPHIGRNISIY 468
            ...|...|..:.::..|||..||:..||..:|||..|||.|:     :.|:.|.|        ||
Mouse   410 HVKITYRDGLTGELGYLNPGVFTQSRRWKDHADMLKQYATCLSLLLPKYNVTEPQ--------IY 466

  Fly   469 FDIWCSMNGRFQQRSFDPREDLLRAKWSPFESTSWSLPLLNELNHMRPKLRTIETEVLAWNNYSD 533
            ||||.|:|.|||||.||||.|:::|.||||:.|.|..|||.:|:..|.||:.|::.:   :|:::
Mouse   467 FDIWVSINDRFQQRLFDPRVDIVQAVWSPFQRTPWVQPLLMDLSPWRTKLQDIKSSL---DNHTE 528

  Fly   534 VIFVADFPGLTLTNFISPDLINCTLTILEGNVRYRNERDPEAYFLTAGKSIGLESNITHLVTTIG 598
            |:|:||||||.|.||:|.||.|.::.:|:|.|......:.:...|..|:.:.|.:...|.|.|:.
Mouse   529 VVFIADFPGLHLENFVSEDLGNTSIQLLQGEVTVELVAEQKNQTLQEGEKMQLPAGEYHKVYTVS 593

  Fly   599 QKPASYLFTYTNKTMLEQGITIEQPDTEERSVLPLWQEFQHRVTN 643
            ..|:.|::.|.|.|    .:.:||.       |...||.:.:|.|
Mouse   594 SSPSCYMYVYVNTT----EVALEQD-------LAYLQELKEKVEN 627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GC	NP_001163323.1	HTTM	73..330	CDD:214802	123/258 (48%)
		VKG_Carbox	83..505	CDD:282887	206/444 (46%)
		cupin_like	<557..608	CDD:304367	11/50 (22%)
Ggcx	NP_062776.1	HTTM	56..315	CDD:214802	123/258 (48%)
		VKG_Carbox	66..502	CDD:282887	205/443 (46%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	729..757

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837668
Domainoid	1	1.000	395	1.000	Domainoid score	I760
eggNOG	1	0.900	-	-		E1_28JF2
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H639
Inparanoid	1	1.050	487	1.000	Inparanoid score	I1413
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG50094
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0008238
OrthoInspector	1	1.000	-	-		oto94439
orthoMCL	1	0.900	-	-		OOG6_105840
Panther	1	1.100	-	-	LDO	PTHR12639
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5771
SonicParanoid	1	1.000	-	-		X6209
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790