Protein Alignment ABCB7 and abcb7

DIOPT Version :10

• Sequence 1: NP_728642.2
• Gene: ABCB7 / 38193
• FlyBaseID: FBgn0035244
• Length: 743
• Species: Drosophila melanogaster
• Sequence 2: NP_001410903.2
• Gene: abcb7 / 566515
• ZFINID: ZDB-GENE-050517-10
• Length: 743
• Species: Danio rerio
• Alignment Length: 746
• Identity: 397/746 - (53%)
• Similarity: 505/746 - (67%)
• Gaps: 58/746 - (7%)

  Fly    23 KCYTLAKGPGTHVQARVLYSSLTK--------VDDKNSSDAKRKKITPFTPTPGSKLLGGVFGKK 79
            ||       |.|:|.|.|...|.:        ..|..:::.::::.|.....|
Zfish     9 KC-------GFHMQRRKLSLLLQRSSAVQAWTFHDHRAANKRKERNTYLLSDP------------ 54

  Fly    80 AKGGAPAAAAAKTTTLQRQRPYRPQQQQSRLCHVHI-------GGGSDGGSGLGKLDAPEVTSKD 137
                     :.:::|....|....||....:.|:|:       |....|.|...|....||.|..
Zfish    55 ---------SRESSTWANNRGQNSQQILEAVKHLHLQERQCWHGNAGGGLSADPKNVLKEVNSSK 110

  Fly   138 MLRAMMAYIWPKEDPLVRKRVGISLGLLAGSKLLTVCVPFLFKGAVDTMT-----TLNMDTAPDA 197
            :|.||..|:|||:.|.:|.||.|||.||||:|:..|.|||:||.|||::.     .||:..||:.
Zfish   111 ILGAMFTYVWPKDRPDLRARVVISLSLLAGAKITNVIVPFMFKYAVDSLNQMSGHMLNLSDAPNT 175

  Fly   198 VLSAATALMLGYGIARASAAGFNELRNAVFAKVAHHSIRKIASNVFLHLHNLDLAFHLNKQTGAL 262
            |::.|||:::|||::|..:|.|||||||||.|||..|||:||.|||||||||||.|||::|||||
Zfish   176 VVTMATAVLIGYGVSRTGSALFNELRNAVFGKVAQSSIRRIAKNVFLHLHNLDLGFHLSRQTGAL 240

  Fly   263 SKTIDRGSRGINFVLSAMVFNIVPTIFELALVSSILGVKCGLAFAGVSMGCVGIYAAYTLSVTQW 327
            ||.||||:|||:|||||:|||:.||:||:.|||.||..|||..||.|::|.:..|.|:|::||||
Zfish   241 SKAIDRGTRGISFVLSALVFNLGPTLFEMMLVSGILYYKCGGHFALVTLGTLSAYTAFTVAVTQW 305

  Fly   328 RTQFRVFMNQAENEAGNKAVDSLINYETVKYFNNEKYEAGCYNEVLKKYEAASLKTSSSLALLNF 392
            |||||:.||:|:|||||.|:|||:|||||||||||||||..|:..||.||::||||:|:||:|||
Zfish   306 RTQFRIEMNKADNEAGNAAIDSLLNYETVKYFNNEKYEAERYDGFLKVYESSSLKTTSTLAMLNF 370

  Fly   393 GQNAIFSSALSLIMVLAAKEIAQGNMTVGDLVMVNALLFQLSIPLGFLGSVYREVRQALLDMRAM 457
            ||:||||..|:.|||||:|.|..|.||||||||||.||||||:||.|||:||||.||||:||..:
Zfish   371 GQSAIFSVGLTAIMVLASKGIMSGTMTVGDLVMVNGLLFQLSLPLNFLGTVYRETRQALIDMNTL 435

  Fly   458 FTLMNVDSSIQTAANAQPLFVDTTNSSIEFRNVSFEYEPGKPIFRDLSFTIPAGKNVAIVGGSGS 522
            |||::||:.|:....|.||.|....::|.|.:|.|||..|:.:...:||.:||||.|||||||||
Zfish   436 FTLLSVDTKIKEKEMAPPLIVTPQEATIRFEDVYFEYLEGQKVLNGVSFEVPAGKKVAIVGGSGS 500

  Fly   523 GKSSMVRLLFRFFEPNSGKVLIGGQDISAVDLESLRKVIAVVPQDSVLFHNTIEHNIHYGNLSKS 587
            |||::|||||||:||..|.:.|.||:|..|.||||||.:.|||||:|||||||.:|:.|||::.:
Zfish   501 GKSTIVRLLFRFYEPQQGNIYIAGQNIRDVGLESLRKAVGVVPQDAVLFHNTIFYNLMYGNINAT 565

  Fly   588 HAEVQNAARMADLHDSIMSWPGQYSTQVGERGLKLSGGEKQRVAIARAILKNTPILIFDEATSSL 652
            ..:|...||:|.:||:|:..|.:|.|||||||||||||||||||||||||||.|||::|||||||
Zfish   566 AEDVYRVARLAGIHDAILKMPHKYDTQVGERGLKLSGGEKQRVAIARAILKNPPILLYDEATSSL 630

  Fly   653 DSITEHNILQALTRATSGRTSICIAHRLSTVKDADEILVLENGRVGERGTHSELLRQNG-LYARL 716
            ||:||.|||.::......|||:.|||||||:.|||||:||..|:|.|||.|..||...| |||.|
Zfish   631 DSVTEENILTSMKEMVKDRTSVFIAHRLSTIVDADEIIVLNQGKVAERGNHQTLLDTPGSLYANL 695

  Fly   717 WETQTQQF---------DPSREINEEVAAKK 738
            |.||..:.         .|.|...:|...||
Zfish   696 WNTQNSRILSNGSKPEPVPERVSQKEEERKK 726

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ABCB7	NP_728642.2	ATM1	147..732	CDD:444078	366/599 (61%)
abcb7	NP_001410903.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	45..64		3/39 (8%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	703..724		3/20 (15%)