Protein Alignment ABCB7 and abcb6a

DIOPT Version :9

• Sequence 1: NP_728642.2
• Gene: ABCB7 / 38193
• FlyBaseID: FBgn0035244
• Length: 743
• Species: Drosophila melanogaster
• Sequence 2: XP_005160347.1
• Gene: abcb6a / 564067
• ZFINID: ZDB-GENE-050517-9
• Length: 851
• Species: Danio rerio
• Alignment Length: 629
• Identity: 262/629 - (41%)
• Similarity: 380/629 - (60%)
• Gaps: 19/629 - (3%)

  Fly   121 GGSGLGKLDAPEVTSKDM---LRAMMAYIWPKEDPLVRKRVGISLGLLAGSKLLTVCVPFLFKGA 182
            |...||..|..:.|.||.   :|.::.|:|||...|::..|.:.||:|...:.:.|.||..:|..
Zfish   217 GAPLLGNSDEDQSTWKDFGKKVRLLVPYMWPKGSVLLQLLVLMCLGMLGIERAINVFVPIYYKNI 281

  Fly   183 VDTMT------TLNMDTAPDAVLSAATALMLGYGIARASAAGF-NELRNAVFAKVAHHSIRKIAS 240
            |:.:|      ||.|......:|.    .:.|.|   |.|:|| :.||:.::.:|..::.|.:..
Zfish   282 VNQLTDGSSWKTLAMTVCVYCLLK----FLQGGG---AGASGFVSNLRSFLWIRVQQYTNRVVQV 339

  Fly   241 NVFLHLHNLDLAFHLNKQTGALSKTIDRGSRGINFVLSAMVFNIVPTIFELALVSSILGVKCGLA 305
            .:|.|||.|.|.:||.::||.:.::||||:..||.:||.:||:|.|||.::.:............
Zfish   340 RLFAHLHALSLRWHLGRRTGDVLRSIDRGTSSINSLLSYIVFSIFPTIADIVIAIVYFISNFNAW 404

  Fly   306 FAGVSMGCVGIYAAYTLSVTQWRTQFRVFMNQAENEAGNKAVDSLINYETVKYFNNEKYEAGCYN 370
            |..:...|:.:|...|:.:|:|||::|..||..:|.|.:||||||:|:|||||:|.|.||.|.:.
Zfish   405 FGLIVFVCMALYLTLTIFITEWRTKYRRDMNTQDNNAKSKAVDSLLNFETVKYYNAESYEVGRFE 469

  Fly   371 EVLKKYEAASLKTSSSLALLNFGQNAIFSSALSLIMVLAAKEIAQGNMTVGDLVMVNALLFQLSI 435
            :.:.||:.:..||::||||||..||.|....|....:|.|..:.:|...|||.|:....:.||..
Zfish   470 DAILKYQVSEWKTNASLALLNQTQNLIIGLGLLTGSLLCAYFVTEGKFQVGDYVLFGTYIIQLYT 534

  Fly   436 PLGFLGSVYREVRQALLDMRAMFTLMNVDSSIQTAANAQPLFVDTTNSSIEFRNVSFEYEPGKPI 500
            ||.:.|:.||.::.:.:||.:||.|...:..::...||..|:.  ....:||.||.|.|..||.|
Zfish   535 PLNWFGTYYRMIQNSFIDMESMFKLFTEEEEVKDEVNAGNLYF--RQGKVEFENVFFSYTQGKEI 597

  Fly   501 FRDLSFTIPAGKNVAIVGGSGSGKSSMVRLLFRFFEPNSGKVLIGGQDISAVDLESLRKVIAVVP 565
            .:|:|||:..|:.||:||.||||||:::||||||::...|.:.|.|||||.|...|||..|.|||
Zfish   598 LKDVSFTVLPGQTVALVGQSGSGKSTIIRLLFRFYDVQGGCIKIDGQDISKVKQSSLRAHIGVVP 662

  Fly   566 QDSVLFHNTIEHNIHYGNLSKSHAEVQNAARMADLHDSIMSWPGQYSTQVGERGLKLSGGEKQRV 630
            ||:|||::.|..||.||.::.:..||:.||..||:||.|:.:|..|.||||||||||||||||||
Zfish   663 QDTVLFNDNIRDNIRYGRVTATDQEVEEAAIAADIHDKIIGFPDGYETQVGERGLKLSGGEKQRV 727

  Fly   631 AIARAILKNTPILIFDEATSSLDSITEHNILQALTRATSGRTSICIAHRLSTVKDADEILVLENG 695
            ||||.|||...|::.|||||:||:.||.||..:|.:..:.||::.:||||||:..||.||||.:|
Zfish   728 AIARTILKAPQIILLDEATSALDTQTERNIQASLAKVCANRTTVVVAHRLSTIIGADVILVLRDG 792

  Fly   696 RVGERGTHSELLRQNGLYARLWETQTQQFDPSREINEEVAAKKT 739
            ::.|||.|.|||.:.|||:.:|:.|.|..|.....:.|...:|:
Zfish   793 QIVERGRHEELLAKGGLYSDMWQKQQQAQDSDSASDSETKDRKS 836

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ABCB7	NP_728642.2	ABC_membrane	164..437	CDD:294371	98/279 (35%)
		ATM1	222..717	CDD:227590	223/494 (45%)
		P-loop_NTPase	485..720	CDD:304359	130/234 (56%)
abcb6a	XP_005160347.1	MTABC_N	6..247	CDD:292803	9/29 (31%)
		ABC_membrane	269..536	CDD:279056	97/273 (36%)
		ATM1	321..816	CDD:227590	224/496 (45%)
		ABCC_ATM1_transporter	582..817	CDD:213220	130/234 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5265
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D248727at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820