Protein Alignment ABCB7 and Abcb7

DIOPT Version :10

• Sequence 1: NP_728642.2
• Gene: ABCB7 / 38193
• FlyBaseID: FBgn0035244
• Length: 743
• Species: Drosophila melanogaster
• Sequence 2: NP_997683.1
• Gene: Abcb7 / 302395
• RGDID: 1303086
• Length: 752
• Species: Rattus norvegicus
• Alignment Length: 705
• Identity: 384/705 - (54%)
• Similarity: 504/705 - (71%)
• Gaps: 39/705 - (5%)

  Fly    68 GSKLLGGVFGKKAKGGA---PAAAAAKTTTLQRQRPYRPQQQ-------------QSRLC-HVHI 115
            ||.|....:...|.|.|   ....:.:.:|.||......:|.             :.|.| |.|.
  Rat    36 GSGLRWSSYQSGASGSARLSQTTESLRNSTQQRWEKNNSRQLLDASKVLQAWPLIEKRTCWHGHA 100

  Fly   116 GGG--SDGGSGLGKLDAPEVTSKDMLRAMMAYIWPKEDPLVRKRVGISLGLLAGSKLLTVCVPFL 178
            |||  :|...||     .:|.::.:::||::|:|||:.|.:|.||.||||.|.|:|.:.:.|||:
  Rat   101 GGGLHTDPKEGL-----KDVDTRKIIKAMLSYVWPKDRPDLRARVAISLGFLGGAKAMNIVVPFM 160

  Fly   179 FKGAVDTM-----TTLNMDTAPDAVLSAATALMLGYGIARASAAGFNELRNAVFAKVAHHSIRKI 238
            ||.|||::     ..||:..||:.|.:.|||:::|||::||.||.|||:|||||.|||.:|||:|
  Rat   161 FKYAVDSLNQMSGNMLNLSDAPNTVATMATAVLIGYGVSRAGAAFFNEVRNAVFGKVAQNSIRRI 225

  Fly   239 ASNVFLHLHNLDLAFHLNKQTGALSKTIDRGSRGINFVLSAMVFNIVPTIFELALVSSILGVKCG 303
            |.|||||||||||.|||::|||||||.||||:|||:|||||:|||::|.:||:.||||:|..|||
  Rat   226 AKNVFLHLHNLDLGFHLSRQTGALSKAIDRGTRGISFVLSALVFNLLPIVFEMTLVSSVLYYKCG 290

  Fly   304 LAFAGVSMGCVGIYAAYTLSVTQWRTQFRVFMNQAENEAGNKAVDSLINYETVKYFNNEKYEAGC 368
            ..||.|::|.:|.|.|:|::||:|||:||:.||:|:|:|||.|:|||:|||||||||||||||..
  Rat   291 AQFALVTLGTLGAYTAFTVAVTRWRTRFRIEMNKADNDAGNAAIDSLLNYETVKYFNNEKYEAQR 355

  Fly   369 YNEVLKKYEAASLKTSSSLALLNFGQNAIFSSALSLIMVLAAKEIAQGNMTVGDLVMVNALLFQL 433
            |:..||.||.||||::|:||:|||||:||||..|:.|||||::.|..|.:|||||||||.|||||
  Rat   356 YDGFLKTYETASLKSTSTLAMLNFGQSAIFSVGLTAIMVLASQGIVAGALTVGDLVMVNGLLFQL 420

  Fly   434 SIPLGFLGSVYREVRQALLDMRAMFTLMNVDSSIQTAANAQPLFVDTTNSSIEFRNVSFEYEPGK 498
            |:||.|||:||||.||||:||..:|||:.||:.|:..|.|.||.:....:::.|.||.|||..|:
  Rat   421 SLPLNFLGTVYRETRQALIDMNTLFTLLKVDTRIKDKAMASPLQITPQTATVAFDNVHFEYIEGQ 485

  Fly   499 PIFRDLSFTIPAGKNVAIVGGSGSGKSSMVRLLFRFFEPNSGKVLIGGQDISAVDLESLRKVIAV 563
            .:...:||.:||||.||||||||||||::|||||||:||..|.:.:.||:|..|.|||||:.:.|
  Rat   486 KVLSGVSFEVPAGKKVAIVGGSGSGKSTIVRLLFRFYEPQKGSIYLAGQNIQDVSLESLRRAVGV 550

  Fly   564 VPQDSVLFHNTIEHNIHYGNLSKSHAEVQNAARMADLHDSIMSWPGQYSTQVGERGLKLSGGEKQ 628
            ||||:|||||||.:|:.|||::.|..||...|::|.|||:|:..|..|.||||||||||||||||
  Rat   551 VPQDAVLFHNTIYYNLLYGNINASPEEVYAVAKLAGLHDAILRMPHGYDTQVGERGLKLSGGEKQ 615

  Fly   629 RVAIARAILKNTPILIFDEATSSLDSITEHNILQALTRATSGRTSICIAHRLSTVKDADEILVLE 693
            ||||||||||:.|::::||||||||||||..||.|:......||||.||||||||.|||||:||.
  Rat   616 RVAIARAILKDPPVILYDEATSSLDSITEETILGAMRDVVKHRTSIFIAHRLSTVVDADEIIVLS 680

  Fly   694 NGRVGERGTHSELL-RQNGLYARLWETQTQQ--------FDPSRE-INEEVAAKK 738
            .|:|.|||||..|| ..:.:|:.:|.||:.:        :|..:| :::|...||
  Rat   681 QGKVAERGTHYGLLANSSSIYSEMWHTQSTRIQNHDNLGWDAKKESLSKEEERKK 735

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ABCB7	NP_728642.2	ATM1	147..732	CDD:444078	357/599 (60%)
Abcb7	NP_997683.1	ATM1	125..709	CDD:444078	355/583 (61%)