Protein Alignment ABCB7 and abtm-1

DIOPT Version :9

• Sequence 1: NP_728642.2
• Gene: ABCB7 / 38193
• FlyBaseID: FBgn0035244
• Length: 743
• Species: Drosophila melanogaster
• Sequence 2: NP_001021830.1
• Gene: abtm-1 / 171807
• WormBaseID: WBGene00022281
• Length: 704
• Species: Caenorhabditis elegans
• Alignment Length: 644
• Identity: 347/644 - (53%)
• Similarity: 460/644 - (71%)
• Gaps: 28/644 - (4%)

  Fly   108 SRLCHVHIGGGSD---GGSGLGKLDAPEVTSKDMLRAMMAYIWPKEDPLVRKRVGISLGLLAGSK 169
            :|.| .|.|..|.   ..||       :::...:::.::.::|||:.|.:::||.::|.||..:|
 Worm    55 TRTC-FHPGASSQVPLQASG-------QLSGYQLVQRLLKFVWPKDKPEIKRRVLVALCLLIAAK 111

  Fly   170 LLTVCVPFL-------FKGAVDTMTTLNMDTAP-DAVLSAATALMLGYGIARASAAGFNELRNAV 226
            |..|.||||       :.|.......|..|..| ..:.:|..|..:.||||||:|:.||||||||
 Worm   112 LANVSVPFLLRDIVNYYNGKAPEFLKLTFDGTPSQTIFTAGIATCIAYGIARATASLFNELRNAV 176

  Fly   227 FAKVAHHSIRKIASNVFLHLHNLDLAFHLNKQTGALSKTIDRGSRGINFVLSAMVFNIVPTIFEL 291
            |||||.:|||.|:.::|||||:|||:||||:|||||||.||||:||::||||:::||::||..|:
 Worm   177 FAKVAQNSIRSISRSIFLHLHSLDLSFHLNRQTGALSKAIDRGTRGMSFVLSSLIFNLIPTAVEI 241

  Fly   292 ALVSSILGVKCGLAFAGVSMGCVGIYAAYTLSVTQWRTQFRVFMNQAENEAGNKAVDSLINYETV 356
            .:||::.....|..||.::||.:|:|...||.||:|||:||..||||:|:|||||:|||||||||
 Worm   242 GMVSALFTGTLGPEFAYMTMGSIGMYGIATLGVTKWRTKFRHQMNQADNDAGNKAIDSLINYETV 306

  Fly   357 KYFNNEKYEAGCYNEVLKKYEAASLKTSSSLALLNFGQNAIFSSALSLIMVLAAKEIAQGNMTVG 421
            |||||||:||..|:..|||||.|||||:||||||||.||||||.||..:|.:|...||.|::|:|
 Worm   307 KYFNNEKFEADRYDHFLKKYEGASLKTTSSLALLNFTQNAIFSGALIGVMCMAGTRIAAGDLTIG 371

  Fly   422 DLVMVNALLFQLSIPLGFLGSVYREVRQALLDMRAMFTLMNVDSSIQTAANAQPLFVDTTNSSIE 486
            ||::.|.|||||||||.|||||||||||.|:||..||:|:.:...|..||:|:.|.:...:.|::
 Worm   372 DLILANTLLFQLSIPLNFLGSVYREVRQGLVDMNQMFSLLTLKPKIVEAADAKRLEIVDNDISLK 436

  Fly   487 FRNVSFEYEPGKPIFRDLSFTIPAGKNVAIVGGSGSGKSSMVRLLFRFFEPNSGKVLIGGQDISA 551
            |.||.|.|.|.|||.:.|...||.||.||||||||||||::||||:|.::..||.|.|.|.:...
 Worm   437 FENVHFGYLPEKPILKGLDLEIPVGKKVAIVGGSGSGKSTIVRLLYRLYDTESGNVRINGLETRD 501

  Fly   552 VDLESLRKVIAVVPQDSVLFHNTIEHNIHYGNLSKSHAEVQNAARMADLHDSIMSWPGQYSTQVG 616
            :.|:|||:.|::|||||||||:||.:|:.||..|.|..||..||::||||:|:::.|..|.|.||
 Worm   502 LTLDSLRQSISIVPQDSVLFHDTIFYNLAYGRPSASMEEVYQAAKLADLHESVLAMPNGYETLVG 566

  Fly   617 ERGLKLSGGEKQRVAIARAILKNTPILIFDEATSSLDSITEHNILQALTRATSGRTSICIAHRLS 681
            |||||||||||||||||||||||.|.:|:||||||||:|||.||::||..|...|||:.|||||:
 Worm   567 ERGLKLSGGEKQRVAIARAILKNAPFVIYDEATSSLDAITESNIMKALKGAVEKRTSLFIAHRLA 631

  Fly   682 TVKDADEILVLENGRVGERGTHSELLRQNGLYARLWETQTQQFDPSREINEEVAAKKTR 740
            |:.|||.|.||::|:|.|:|:|.:||..:||||:||::|.         ...||.||::
 Worm   632 TIVDADIIYVLQDGKVAEKGSHFDLLAVDGLYAQLWKSQN---------IHGVAPKKSK 681

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ABCB7	NP_728642.2	ABC_membrane	164..437	CDD:294371	163/280 (58%)
		ATM1	222..717	CDD:227590	301/494 (61%)
		P-loop_NTPase	485..720	CDD:304359	140/234 (60%)
abtm-1	NP_001021830.1	ABC_membrane	104..387	CDD:294371	164/282 (58%)
		ATM1	172..667	CDD:227590	301/494 (61%)
		P-loop_NTPase	437..670	CDD:304359	140/232 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157573
Domainoid	1	1.000	320	1.000	Domainoid score	I661
eggNOG	1	0.900	-	-		E1_COG5265
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3175
Inparanoid	1	1.050	656	1.000	Inparanoid score	I410
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53794
OrthoDB	1	1.010	-	-		D248727at2759
OrthoFinder	1	1.000	-	-		FOG0003749
OrthoInspector	1	1.000	-	-		oto20193
orthoMCL	1	0.900	-	-		OOG6_101840
Panther	1	1.100	-	-	LDO	PTHR24221
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2158
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770