Protein Alignment ABCB7 and Hmt-1

DIOPT Version :10

• Sequence 1: NP_728642.2
• Gene: ABCB7 / 38193
• FlyBaseID: FBgn0035244
• Length: 743
• Species: Drosophila melanogaster
• Sequence 2: XP_061503102.1
• Gene: Hmt-1 / 1269280
• VectorBaseID: AGAMI1_013986
• Length: 849
• Species: Anopheles gambiae
• Alignment Length: 626
• Identity: 248/626 - (39%)
• Similarity: 378/626 - (60%)
• Gaps: 35/626 - (5%)

  Fly   128 LDAPEVTSKDM-----------------------LRAMMAYIWPKEDPLVRKRVGISLGLLAGSK 169
            |.||.:||...                       :|.::.::|||:|.|::.||.....||...:
Mosquito   192 LKAPGITSTQFTEEYHHLHQAQENRSTFANAWTKMRTLLPFLWPKKDALLQFRVVFCFLLLIAGR 256

  Fly   170 LLTVCVPFLFKGAVDTMTTLNMDTAPDAVLSAATALMLGYGIARASAAG----FNELRNAVFAKV 230
            |:.|.|....|..||::|........|.:|     |.:|:...:....|    .|.||:.::.::
Mosquito   257 LINVYVQIYNKKIVDSLTEKPTVFRWDWIL-----LYVGFKFLQGGGTGSMGLLNNLRSFLWIRI 316

  Fly   231 AHHSIRKIASNVFLHLHNLDLAFHLNKQTGALSKTIDRGSRGINFVLSAMVFNIVPTIFELALVS 295
            ..::.|:|...:|.|||:|.|.:|||::||.:.:.:|||:..||.:|:.::|:|.|||.::.:..
Mosquito   317 QQYTTREIELELFRHLHSLSLRWHLNRKTGEVLRVMDRGTDSINNLLNYILFSITPTIVDILIAV 381

  Fly   296 SILGVKCGLAFAGVSMGCVGIYAAYTLSVTQWRTQFRVFMNQAENEAGNKAVDSLINYETVKYFN 360
            ..........|..:....:.:|...|:.||:|||:|:..||.|:|:...::||||:|:|||||:.
Mosquito   382 VFFITAFNWWFGFIVFLTMTLYIVATIMVTEWRTKFQRRMNLADNQQKARSVDSLLNFETVKYYG 446

  Fly   361 NEKYEAGCYNEVLKKYEAASLKTSSSLALLNFGQNAIFSSALSLIMVLAAKEIA-QGNMTVGDLV 424
            .|:||..||.:.:.|::....::..:|.:||..||.|....|....:|.|..:. :..:||||.|
Mosquito   447 AEQYEVSCYRDAILKFQDEEWRSIITLNILNTMQNIIVCGGLLAGSLLCAYLVVYEEGLTVGDYV 511

  Fly   425 MVNALLFQLSIPLGFLGSVYREVRQALLDMRAMFTLMNVDSSIQTAANAQPLFVDTTNSSIEFRN 489
            :..:.:.||.:||.:.|:.||.:::..:||..||.||..|..:..|.:|..|.|  ....|:|.:
Mosquito   512 LFASYIIQLYVPLNWFGTFYRAIQKNFVDMENMFELMREDQEVVDAPSAPGLAV--ARGRIDFND 574

  Fly   490 VSFEYEPGKPIFRDLSFTIPAGKNVAIVGGSGSGKSSMVRLLFRFFEPNSGKVLIGGQDISAVDL 554
            |:|.|...:.:.|::||::|.||.|||||.||:|||:::||||||::.|:|.:|:.||:|..|..
Mosquito   575 VTFGYNAERLVLRNVSFSVPGGKTVAIVGPSGAGKSTIMRLLFRFYDVNNGSILVDGQNIKTVRQ 639

  Fly   555 ESLRKVIAVVPQDSVLFHNTIEHNIHYGNLSKSHAEVQNAARMADLHDSIMSWPGQYSTQVGERG 619
            .|||:.|.|||||:|||:|||::||.||.:....|:|..|||.||:|:.|:::|.||.|||||||
Mosquito   640 ASLRQAIGVVPQDTVLFNNTIKYNIQYGRVGAPEADVIMAARSADIHERILTFPEQYETQVGERG 704

  Fly   620 LKLSGGEKQRVAIARAILKNTPILIFDEATSSLDSITEHNILQALTRATSGRTSICIAHRLSTVK 684
            |:|||||||||||||.|||:..|::.|||||:||:.||.||..||.:..:.||:|.|||||||:.
Mosquito   705 LRLSGGEKQRVAIARTILKSPAIVLLDEATSALDTQTERNIQSALAKVCANRTTIIIAHRLSTII 769

  Fly   685 DADEILVLENGRVGERGTHSELLRQNGLYARLWETQTQQFD 725
            .|||||||::|.:.|||.|..||.|:|:||.:|..|.:..:
Mosquito   770 HADEILVLKDGSIVERGRHDNLLEQSGVYAEMWNQQLKNLE 810

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ABCB7	NP_728642.2	ATM1	147..732	CDD:444078	242/584 (41%)
Hmt-1	XP_061503102.1	None