Protein Alignment CG12104 and TOX2

DIOPT Version :9

• Sequence 1: NP_001261267.1
• Gene: CG12104 / 38187
• FlyBaseID: FBgn0035238
• Length: 250
• Species: Drosophila melanogaster
• Sequence 2: XP_006723947.1
• Gene: TOX2 / 84969
• HGNCID: 16095
• Length: 515
• Species: Homo sapiens
• Alignment Length: 313
• Identity: 75/313 - (23%)
• Similarity: 107/313 - (34%)
• Gaps: 108/313 - (34%)

  Fly    25 SPSQASRRMLSLDQSMLNDDDEENCDTYASG----------GGQNLLVQPEQQQNQAMAQAPPKP 79
            |||....:..:...|....::|.......||          ..:|...:.::..|:     |.||
Human   199 SPSPPGSKSATPSPSSSTQEEESEVHFKISGEKRPSADPGKKAKNPKKKKKKDPNE-----PQKP 258

  Fly    80 LAPFALFFRDTVTAIKQQNPTCSLEQMQVIVQTMWESLDETQKNVYALRHEQEKREYVRLMRGYR 144
            ::.:|||||||..|||.|||:.:...:..||.:||:||.|.||..|..:.|..|:||::.:..||
Human   259 VSAYALFFRDTQAAIKGQNPSATFGDVSKIVASMWDSLGEEQKQAYKRKTEAAKKEYLKALAAYR 323

  Fly   145 HQLSESEGTSEAEA------PPA--VATNQP----PPLVTTKLESVEDLQ--------------- 182
            ..|.......:.|.      |||  :...||    |.|.:....|  |||
Human   324 ASLVSKSSPDQGETKSTQANPPAKMLPPKQPMYAMPGLASFLTPS--DLQAFRSGASPASLARTL 386

  Fly   183 ------QSVDAQQEPPPD-----------------QIQLLTE-----------------AARVQ- 206
                  ..:.|...|||.                 |..||:.                 |.:||
Human   387 GSKSLLPGLSASPPPPPSFPLSPTLHQQLSLPPHAQGALLSPPVSMSPAPQPPVLPTPMALQVQL 451

  Fly   207 ------------------KCTREQCNKPAIINP----DWEDEYCSNECVVIHC 237
                              ..:...|: |...||    ||:..|.|.||.:..|
Human   452 AMSPSPPGPQDFPHISEFPSSSGSCS-PGPSNPTSSGDWDSSYPSGECGISTC 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12104	NP_001261267.1	HMG-box	76..140	CDD:238037	30/63 (48%)
TOX2	XP_006723947.1	HMG-box	255..320	CDD:238037	30/64 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	73	1.000	Domainoid score	I9245
eggNOG	1	0.900	-	-		E1_COG5648
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000742
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	4	3.860