DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12104 and UBTFL1

DIOPT Version :9

Sequence 1:	NP_001261267.1	Gene:	CG12104 / 38187	FlyBaseID:	FBgn0035238	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	NP_001137447.1	Gene:	UBTFL1 / 642623	HGNCID:	14533	Length:	393	Species:	Homo sapiens

Alignment Length:	164	Identity:	30/164 - (18%)
Similarity:	64/164 - (39%)	Gaps:	16/164 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 EENCDTYASGGGQNLLVQPEQ--------QQNQAMAQAPPKPLAPFALFFRDTVTAIKQQNPTCS 102
            |.:|:....|..:.|:::.::        |:.:.....|.:||..:..||:::.....|..|...
Human    62 EISCNLRKFGTLKELVLEAKKCVKKMNKSQKYRNGPDFPKRPLTAYNRFFKESWPQYSQMYPGMR 126

  Fly   103 LEQMQVIVQTMWESLDETQKNVYALRHEQEKREYVRLMRGYRHQLSESEGTSEAEAPPAVATNQP 167
            .:::..|:...:..|.|..|..|.....:||:|:...:..:|.:..:....::..:......|:.
Human   127 SQELTKILSKKYRELPEQMKQKYIQDFRKEKQEFEEKLARFREEHPDLVQKAKKSSVSKRTQNKV 191

  Fly   168 PPLVTTKLESVEDLQQS------VDAQQEP--PP 193
            .......:|.|..|.::      |....||  ||
Human   192 QKKFQKNIEEVRSLPKTDRFFKKVKFHGEPQKPP 225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12104	NP_001261267.1	HMG-box	76..140	CDD:238037	15/63 (24%)
UBTFL1	NP_001137447.1	HMGB-UBF_HMG-box	100..165	CDD:238686	15/64 (23%)
		HMGB-UBF_HMG-box	223..285	CDD:238686	2/3 (67%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	308..393
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5648
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900