DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12104 and tox3

DIOPT Version :9

Sequence 1:	NP_001261267.1	Gene:	CG12104 / 38187	FlyBaseID:	FBgn0035238	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	XP_005169075.1	Gene:	tox3 / 555286	ZFINID:	ZDB-GENE-090312-209	Length:	587	Species:	Danio rerio

Alignment Length:	207	Identity:	59/207 - (28%)
Similarity:	95/207 - (45%)	Gaps:	28/207 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 LTDTPAESQSPS-QASRRMLSLDQSMLNDDDEENCDTY------ASGGGQNLLVQPE--QQQNQA 71
            :|.:.....||| .||:.......|.:|:||:|..:..      |...|:    :|:  :::.:.
Zfish   199 MTGSNIAHTSPSPPASKSATPSPSSSINEDDQEEGNRVIGEKRPAPDAGK----KPKTPKKKKKK 259

  Fly    72 MAQAPPKPLAPFALFFRDTVTAIKQQNPTCSLEQMQVIVQTMWESLDETQKNVYALRHEQEKREY 136
            ....|.||::.:|||||||..|||.|||..:..::..||.:||:.|.|.||.||..:.|..|:||
Zfish   260 DPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDGLGEEQKQVYKSKTEAAKKEY 324

  Fly   137 VRLMRGYRHQLSESEGTSEAEA---------------PPAVATNQPPPLVTTKLESVEDLQQSVD 186
            ::.:..||..|........|||               .||:....|.....:...:.:.|||::.
Zfish   325 LKALAAYRASLVSKAAAESAEAQTIRSVQQTLASTSLSPALVLPSPLSQHPSMSAAAQALQQALP 389

  Fly   187 AQQEPPPDQIQL 198
            ....|.|.|:::
Zfish   390 RAIAPKPLQMRV 401

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12104	NP_001261267.1	HMG-box	76..140	CDD:238037	30/63 (48%)
tox3	XP_005169075.1	HMG-box	264..329	CDD:238037	30/64 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	72	1.000	Domainoid score	I9262
eggNOG	1	0.900	-	-		E1_COG5648
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000742
OrthoInspector	1	1.000	-	-		otm25163
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X923
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	6	5.860