DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12104 and ubtf

DIOPT Version :9

Sequence 1:	NP_001261267.1	Gene:	CG12104 / 38187	FlyBaseID:	FBgn0035238	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	NP_001005395.1	Gene:	ubtf / 368509	ZFINID:	ZDB-GENE-030616-252	Length:	735	Species:	Danio rerio

Alignment Length:	219	Identity:	47/219 - (21%)
Similarity:	94/219 - (42%)	Gaps:	44/219 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 QSPSQASRRML-----SLDQSMLNDDD-----EENCDTYASGGG--QNLLVQPEQQQNQAMAQAP 76
            |.|..:.::.:     ||:|..|.::.     :::.:...:.|.  ::.|.:.|:|........|
Zfish   226 QWPQLSDKKRIKWIAKSLEQHKLYEEKMREFIQQHPEMNMTQGDIVKSSLTKAERQLKDKFDGRP 290

  Fly    77 PKPLA-PFALFFRDTVTAIKQQNPTCSLEQMQVIVQTMWESLDETQKNVYALRHEQEKREYVRLM 140
            .||.: .::||..:.::::|.   ..|.|:| |:....|:.|.:.:|:.|..|.||:|:||...|
Zfish   291 DKPPSNGYSLFCAELMSSMKD---VPSTERM-VMCSQRWKLLKQAEKDAYQKRCEQKKKEYEVEM 351

  Fly   141 RGYRHQLSESE-----------------GTS-------EAEAPPAVATNQPPPLVTTKLESVEDL 181
            ..|...:||.|                 |.|       .::|.|  :..:|.|.::......|:.
Zfish   352 NRYLLSISEEEQQRILSEQKMGSFKKAGGISSPASKKKSSKAKP--SAEKPKPPISAMFIFSEEK 414

  Fly   182 QQSVDAQQEPPPDQIQLLTEAARV 205
            :..: .|::|....::|....||:
Zfish   415 RPKL-KQEKPELSDMELTRLLARM 437

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12104	NP_001261267.1	HMG-box	76..140	CDD:238037	20/64 (31%)
ubtf	NP_001005395.1	HMGB-UBF_HMG-box	104..168	CDD:238686
		HMGB-UBF_HMG-box	189..254	CDD:238686	6/27 (22%)
		HMGB-UBF_HMG-box	292..351	CDD:238686	19/62 (31%)
		HMGB-UBF_HMG-box	400..463	CDD:238686	8/39 (21%)
		HMG_box_5	469..552	CDD:291548
		HMGB-UBF_HMG-box	557..621	CDD:238686
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5648
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900