DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12104 and HMGB3

DIOPT Version :9

Sequence 1:NP_001261267.1 Gene:CG12104 / 38187 FlyBaseID:FBgn0035238 Length:250 Species:Drosophila melanogaster
Sequence 2:NP_001288160.1 Gene:HMGB3 / 3149 HGNCID:5004 Length:220 Species:Homo sapiens


Alignment Length:152 Identity:35/152 - (23%)
Similarity:68/152 - (44%) Gaps:24/152 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly    45 DEENCDTYASGGGQNLLVQPEQQQNQAMAQAPPKPLAPFALFFRDTVTAIKQQNPTCSLEQMQVI 109
            |.|..|...:.||:.     ::..|     ||.:|.:.|.||..:....||..||..|:..:...
Human    92 DREMKDYGPAKGGKK-----KKDPN-----APKRPPSGFFLFCSEFRPKIKSTNPGISIGDVAKK 146

  Fly   110 VQTMWESLDETQKNVYALRHEQEKREYVRLMRGYRHQLSESEGTSE-AEAPPAVATNQPPPLVTT 173
            :..||.:|::::|..|..:..:.|.:|.:.:..|:     |:|..: |:.|..||..        
Human   147 LGEMWNNLNDSEKQPYITKAAKLKEKYEKDVADYK-----SKGKFDGAKGPAKVARK-------- 198

  Fly   174 KLESVEDLQQSVDAQQEPPPDQ 195
            |:|..::.::..:.::|...|:
Human   199 KVEEEDEEEEEEEEEEEEEEDE 220

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12104NP_001261267.1 HMG-box 76..140 CDD:238037 17/63 (27%)
HMGB3NP_001288160.1 HMG_box_2 33..98 CDD:370242 2/5 (40%)
HMG_box 113..180 CDD:366139 17/66 (26%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5648
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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