DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12104 and Tox4

DIOPT Version :9

Sequence 1:NP_001261267.1 Gene:CG12104 / 38187 FlyBaseID:FBgn0035238 Length:250 Species:Drosophila melanogaster
Sequence 2:NP_075923.2 Gene:Tox4 / 268741 MGIID:1915389 Length:619 Species:Mus musculus


Alignment Length:447 Identity:88/447 - (19%)
Similarity:137/447 - (30%) Gaps:223/447 - (49%)


- Green bases have known domain annotations that are detailed below.


  Fly    26 PSQASRRMLSLDQSMLNDDDEENCDTYAS--GGGQNLLVQPEQQQNQAMAQ------APPKPLAP 82
            |:|:....||...|..|...|:..|.:..  ...:.::|:..::|.....:      .|.||::.
Mouse   165 PAQSPEDRLSTTPSPTNSLHEDGVDDFRRQLPAQKTVVVETGKKQKAPKKRKKKDPNEPQKPVSA 229

  Fly    83 FALFFRDTVTAIKQQNPTCSLEQMQVIVQTMWESLDETQKNVYALRHEQEKREYVRLMRGYRHQ- 146
            :|||||||..|||.|||..:..::..||.:||:||.|.||.||..:.|..|:||::.:..|:.. 
Mouse   230 YALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKKEYLKALAAYKDNQ 294

  Fly   147 ------------------------------LSESEGTSEAEA-PPAVATN--------------- 165
                                          .|.:..::|:.| ||.:..|               
Mouse   295 ECQATVETVELDPVPQSQTPSPPPVTAADPASPAPASTESPALPPCIIVNSTLSSYVANQASSGP 359

  Fly   166 ----------------------------------------------------------------- 165
                                                                             
Mouse   360 GGQPNITKLIITKQMLPSSITMSQGGMVTVIPATVVTSRGLQVGQTSTATIQPSQQAQIVTRSVL 424

  Fly   166 -----------------QPPPL-------------VTTKLESVEDLQQ------SVDAQQEPPPD 194
                             |||||             :..:...::.:||      .::.||:|||.
Mouse   425 QAAAAAAASMQLPPPRLQPPPLQQMPQPPTQQQVTILQQPPPLQAMQQPPPQKVRINLQQQPPPL 489

  Fly   195 QIQLL---------------------------TEAARVQ-------------------------- 206
            |.:::                           .||..|:                          
Mouse   490 QSKIVPPPTLKIQTTVVPPTVESSPEQPMNSSPEAHTVEATSPETICEMIADVVPEVESPSQMDV 554

  Fly   207 --------------KCTREQCNKPAIINPDWEDEYCSNECVVIHCRNVFNHWVISMN 249
                          :|.|..|..|.:::.||::|||||||||.|||:||..||.|.|
Mouse   555 ELVSGSPVALSPQPRCVRSGCENPPVVSKDWDNEYCSNECVVKHCRDVFLAWVASRN 611

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12104NP_001261267.1 HMG-box 76..140 CDD:238037 31/63 (49%)
Tox4NP_075923.2 NHP6B 140..>306 CDD:227935 42/140 (30%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 155..227 12/61 (20%)
Nuclear localization signal. /evidence=ECO:0000255 213..218 0/4 (0%)
HMG-box 223..288 CDD:238037 31/64 (48%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 306..335 2/28 (7%)
PHA03160 <464..530 CDD:165431 11/65 (17%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 73 1.000 Domainoid score I9195
eggNOG 1 0.900 - - E1_COG5648
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000742
OrthoInspector 1 1.000 - - otm42995
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R4401
SonicParanoid 1 1.000 - - X923
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
76.890

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