DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12104 and Hmg20b

DIOPT Version :9

Sequence 1:	NP_001261267.1	Gene:	CG12104 / 38187	FlyBaseID:	FBgn0035238	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	XP_006513311.1	Gene:	Hmg20b / 15353	MGIID:	1341190	Length:	415	Species:	Mus musculus

Alignment Length:	144	Identity:	25/144 - (17%)
Similarity:	57/144 - (39%)	Gaps:	28/144 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 PAESQSPSQASRRMLSLDQSMLNDDDEENCDTYASGGGQNLLVQPEQQQ-------------NQA 71
            ||..::|.|....::::.|..          :..|..|:.   .|::::             .:.
Mouse    14 PAGGKTPGQHGAFVVAVKQER----------SEGSRAGEK---GPQEEEPVKKRGWPKGKKRKKI 65

  Fly    72 MAQAPPKPLAPFALFFRDTVTAIKQQNPTCSLEQMQVIVQTMWESLDETQKNVYALRHEQEKREY 136
            :...|..|:..:..|..:....|:.::|.....::..::...|..|...:|..|....|:||::|
Mouse    66 LPNGPKAPVTGYVRFLNERREQIRTRHPDLPFPEITKMLGAEWSKLQPAEKQRYLDEAEKEKQQY 130

  Fly   137 VRLMRGYRHQLSES 150
            ::.:..|  |.||:
Mouse   131 LKELWAY--QQSEA 142

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12104	NP_001261267.1	HMG-box	76..140	CDD:238037	13/63 (21%)
Hmg20b	XP_006513311.1	HMGB-UBF_HMG-box	70..134	CDD:238686	13/63 (21%)
		OmpH	190..>254	CDD:214922
		FAM222A	<314..>400	CDD:373691
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5648
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900