DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13917 and klhl7

DIOPT Version :9

Sequence 1:	NP_001189017.1	Gene:	CG13917 / 38186	FlyBaseID:	FBgn0035237	Length:	2019	Species:	Drosophila melanogaster
Sequence 2:	NP_957171.1	Gene:	klhl7 / 393851	ZFINID:	ZDB-GENE-130212-1	Length:	538	Species:	Danio rerio

Alignment Length:	270	Identity:	57/270 - (21%)
Similarity:	105/270 - (38%)	Gaps:	61/270 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly  1102 ESSLSCRQPRRLGEDLL----KMFLQEIATDMLVEVHGRRIRAHKCILRSRCQYFAAMLAG---H 1159
            |..::.::..||..:::    .:..|.|..|:::.|.|:.|.||:.:|.:...:|:.|...   .
Zfish    17 EKKIASKEEYRLLSNIMGVMNNLRKQGILCDVILVVEGKHILAHRVVLSAASHFFSLMFTSSMME 81

  Fly  1160 GSQSVVSLQGYSYAAVHFALCHIYSGASHPPDGISLMELAALADLLGLEGLKEVTAHALK----- 1219
            .|...|.|.|.....:...:..||: |....:..::..|...|:...::.:|::....||
Zfish    82 ASNHEVELGGAEPEIIELLVEFIYT-ARISVNSNNVQSLLNAANQYQIDPVKKMCVDFLKEQVDA 145

  Fly  1220 TNYCHNFH--KPCSGCSDGILQVLPVALNHALDDLYRKCLRWTCRHYLKVWPTRQFAQLPPDILG 1282
            || |....  ..|..|.:         |..|.||...       :|:..|:...:|.||  |:
Zfish   146 TN-CLGISALAECLNCPE---------LKVAADDFIH-------QHFTNVYKMDEFLQL--DV-- 189

  Fly  1283 RCRQQIVAYMTSDTVL----DTVLDCDHLLAQLSAYRWGHVCEQLVREILEAAYAYVGDHFASL- 1342
               :|:...:..||:.    |.:.|        :|.||      |..::|...: |:.|....:
Zfish   190 ---KQVTHLLQQDTLTVRAEDQIYD--------AAVRW------LKYDVLNRQH-YIVDILGKVR 236

  Fly  1343 --IASDSFLS 1350
              :.|.:|||
Zfish   237 FPLVSKNFLS 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13917	NP_001189017.1	BTB	1117..>1185	CDD:279045	17/74 (23%)
		BTB	1128..>1191	CDD:197585	16/65 (25%)
		BACK	1238..>1281	CDD:197943	10/42 (24%)
klhl7	NP_957171.1	BTB	36..140	CDD:279045	21/104 (20%)
		PHA03098	41..538	CDD:222983	54/246 (22%)
		BACK	148..250	CDD:285009	29/137 (21%)
		KELCH repeat	328..370	CDD:276965
		KELCH repeat	374..418	CDD:276965
		Kelch	385..432	CDD:128874
		KELCH repeat	422..470	CDD:276965
		Kelch	433..482	CDD:128874
		Kelch_1	472..517	CDD:279660
		KELCH repeat	473..517	CDD:276965
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910