DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13917 and rcbtb1

DIOPT Version :9

Sequence 1:	NP_001189017.1	Gene:	CG13917 / 38186	FlyBaseID:	FBgn0035237	Length:	2019	Species:	Drosophila melanogaster
Sequence 2:	NP_956285.1	Gene:	rcbtb1 / 336007	ZFINID:	ZDB-GENE-030131-7951	Length:	531	Species:	Danio rerio

Alignment Length:	187	Identity:	45/187 - (24%)
Similarity:	79/187 - (42%)	Gaps:	34/187 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly  1113 LGEDLLKMFLQEIATDMLVEVHGRRIRAHKCILRSRCQYFAAMLAGHGSQ---SVVSLQGYSYAA 1174
            :.:.|.|.|.....:|:...:.|:.|..||.:|:.||::|.:|...|.::   .|:.:..:||..
Zfish   356 VAQSLKKEFDNPETSDLEFSIDGKYIHVHKAVLKIRCEHFRSMFQSHWNEDMKEVIEIDQFSYPV 420

  Fly  1175 VHFALCHIYSGASH--PPDGISLMELAALADLLGLEGLKEVTAHALKTNYCHN-FHKPCS----- 1231
            ....|..:|:.:..  |.|.|.|::||                    |:||.| ..|.|.
Zfish   421 YRSFLEFLYTDSVDLPPEDAIGLLDLA--------------------TSYCENRLKKLCQHIIKR 465

  Fly  1232 GCS-DGILQVLPVALNHALDDLYRKCLRWTCRHYLKVWPTRQFAQLPPDILGR--CR 1285
            |.: :....:|..|:.:..:||...|.::...|..:|..|..|.|:..::|..  ||
Zfish   466 GITVENAFSLLSAAIRYDAEDLEEFCFKFCVNHLTEVTQTAAFWQIDGNMLKEFICR 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13917	NP_001189017.1	BTB	1117..>1185	CDD:279045	19/70 (27%)
		BTB	1128..>1191	CDD:197585	17/67 (25%)
		BACK	1238..>1281	CDD:197943	10/42 (24%)
rcbtb1	NP_956285.1	RCC1	40..90	CDD:278826
		RCC1_2	77..106	CDD:290274
		RCC1	93..143	CDD:278826
		RCC1	146..196	CDD:278826
		RCC1	199..248	CDD:278826
		RCC1	251..299	CDD:278826
		BTB	360..464	CDD:279045	31/123 (25%)
		BTB	371..467	CDD:197585	28/115 (24%)
		SPOP_C_like	467..525	CDD:269810	13/56 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910