DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG13917 and Klhl21

DIOPT Version :9

Sequence 1:NP_001189017.1 Gene:CG13917 / 38186 FlyBaseID:FBgn0035237 Length:2019 Species:Drosophila melanogaster
Sequence 2:NP_001101466.1 Gene:Klhl21 / 313743 RGDID:1305863 Length:597 Species:Rattus norvegicus


Alignment Length:411 Identity:87/411 - (21%)
Similarity:134/411 - (32%) Gaps:134/411 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly  1135 GRRIRAHKCILRSRCQYFAAMLAGHGSQS---VVSLQGYSYAAVHFALCHIYSGASHPPDGISLM 1196
            ||...||:.:|.:...||.||.||...:|   .|.|.|.....:...|...|:|.. ...|.:..
  Rat    44 GRDFPAHRAVLAAASPYFRAMFAGQLRESRAERVRLHGVPPDMLQLLLDFSYTGRV-AVSGDNAE 107

  Fly  1197 ELAALADLLGLEGLKEVTAHALK-----------TNYCHNFHKPCSGCSDGI------------- 1237
            .|...||||....:||.....|:           .::...|  .|||.:...             
  Rat   108 PLLRAADLLQFPAVKEACGAFLQQQLDLANCLDMQDFAEAF--SCSGLASAAQRFILRHVGELGA 170

  Fly  1238 --LQVLPVA--LNHALDD---------LYRKCLRWT-------CRHYLKVWP----------TRQ 1272
              |:.||:|  |.:..||         .|:..|||.       ..|    ||          .|:
  Rat   171 EQLERLPLARLLRYLRDDGLCVPKEEAAYQLALRWVRADPPRRAAH----WPQLLEAVRLPFVRR 231

  Fly  1273 F------------AQLPP--DILGRCRQ-QIVAYMTSD------------TVLDTVL-------- 1302
            |            |:.||  .:|...|. |...|...|            |.|..:|        
  Rat   232 FYLLAHVEAEPLVARCPPCLRLLREARDFQAARYDRHDRGPCPRMRPRPSTGLAEILVLVGGCDQ 296

  Fly  1303 DCDHLLAQLSAY-----RWGHVCEQLVREILEAAYAYVGDHFASLIASDSFLSLGHDRSR---HI 1359
            |||.|:. :..|     :|.::.|  ..:.|...|:.|.      :.:|.:::.|.|.||   .:
  Rat   297 DCDELVT-VDCYNPQTGQWRYLAE--FPDHLGGGYSIVA------LGNDIYVTGGSDGSRLYDCV 352

  Fly  1360 PRLETLLLHTAAELTPEQACRSYQRVTRLNTVLQAKVIHMPASLGQSELARELQGLQEEQLDWQP 1424
            .|..: .::...|:.|....|.|...:.||.:|..             :|.:    ..|:.|...
  Rat   353 WRYNS-SVNEWTEVAPMLKAREYHSSSVLNGLLYV-------------VAAD----STERYDHAT 399

  Fly  1425 EYIRLVGALVYAVEQCLIRQC 1445
            :....:..:.|.::.|....|
  Rat   400 DSWEALQPMTYPMDNCSTTAC 420

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG13917NP_001189017.1 BTB 1117..>1185 CDD:279045 17/52 (33%)
BTB 1128..>1191 CDD:197585 18/58 (31%)
BACK 1238..>1281 CDD:197943 19/84 (23%)
Klhl21NP_001101466.1 BTB 25..130 CDD:279045 26/86 (30%)
PHA03098 49..547 CDD:222983 85/406 (21%)
BACK 138..239 CDD:285009 20/106 (19%)
Kelch_1 <286..321 CDD:279660 8/37 (22%)
Kelch 1 287..335 11/56 (20%)
KELCH repeat 326..368 CDD:276965 9/48 (19%)
Kelch_1 327..368 CDD:279660 9/47 (19%)
Kelch 2 336..382 11/46 (24%)
Kelch_1 371..409 CDD:279660 8/54 (15%)
KELCH repeat 372..409 CDD:276965 8/53 (15%)
Kelch 3 384..422 7/54 (13%)
KELCH repeat 412..451 CDD:276965 2/9 (22%)
Kelch_1 414..451 CDD:279660 2/7 (29%)
Kelch 4 423..470
Kelch 5 472..512
Kelch_6 502..549 CDD:290672
KELCH repeat 502..548 CDD:276965
Kelch 6 513..560
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 570..597
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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