Protein Alignment CG13917 and Klhl12

DIOPT Version :9

• Sequence 1: NP_001189017.1
• Gene: CG13917 / 38186
• FlyBaseID: FBgn0035237
• Length: 2019
• Species: Drosophila melanogaster
• Sequence 2: XP_038946329.1
• Gene: Klhl12 / 266772
• RGDID: 628717
• Length: 592
• Species: Rattus norvegicus
• Alignment Length: 573
• Identity: 108/573 - (18%)
• Similarity: 188/573 - (32%)
• Gaps: 170/573 - (29%)

  Fly  1081 IQTDLSADSSLASSFSRSGMDESSLSCRQPRRLGEDLLKMFLQEIATDMLVEVHGRRIRAHKCIL 1145
            |.|:..|.|.|.   |.:.:.:|:..|                    |:.:.|..:...||:.:|
  Rat    27 IMTNTHAKSILN---SMNSLRKSNTLC--------------------DVTLRVEQKDFPAHRIVL 68

  Fly  1146 RSRCQYFAAMLAGHGSQSV----------VSLQGYSYAAVHFALCHIYSGASHPPDGISLMELAA 1200
            .:...||.||.....:.|:          |.:||.:.:.:...|..:|:...|.... ::.||..
  Rat    69 AACSDYFCAMFTSEVNASLCYLSEKGKPYVDIQGLTASTMEILLDFVYTETVHVTVE-NVQELLP 132

  Fly  1201 LADLLGLEGLKEVTAHALKTNYCHNFHKPCSGCSDGILQVLPVALNHALDDLYRKCLRWTCRHYL 1265
            .|.||.|:|:|:.....|::..     .| |.|    |.:...|..|...||.:....::.:|:.
  Rat   133 AACLLQLKGVKQACCEFLESQL-----DP-SNC----LGIRDFAETHNCVDLMQAAEVFSQKHFP 187

  Fly  1266 KVWPTRQFAQLPPDILGRCRQQIVAYMTSDTVLDTVLDCDHLLAQL------SAYRWGHVCEQLV 1324
            :|....:|..|                 |...::.::.||.:....      :...|....::..
  Rat   188 EVVQHEEFILL-----------------SQGEVEKLIKCDEIQVDSEEPVFEAVINWVKHAKKER 235

  Fly  1325 REILEAAYAYVGDHFASLIASDSFLSLGHDRSRHIPRLETLLLHTAAELTPEQACRSYQRVTRLN 1389
            .|.|.....||                      .:|.|....:....:..|...|....|    :
  Rat   236 EESLPDLLQYV----------------------RMPLLTPRYITDVIDAEPFIRCSLQCR----D 274

  Fly  1390 TVLQAKVIHMPASLGQSELARELQGLQEEQLDWQPEYIRLVGAL------VYAVEQ--------C 1440
            .|.:||..|:     :.||..::||.:........|.:.:||..      :..||:        .
  Rat   275 LVDEAKKFHL-----RPELRSQMQGPRTRARLGANEVLLVVGGFGSQQSPIDVVEKYDPKTQEWS 334

  Fly  1441 LIRQCSRAMRVTAWQRMDLELRKKIQTL------ARLT--EPLDMKR-QNG-----KPVGKAFSF 1491
            .:...:|..|..|    .:.|..:|..:      :||:  |.||... ::|     .|:......
  Rat   335 FLPSITRKRRYVA----SVSLHDRIYVIGGYDGRSRLSSVECLDYTADEDGVWYSVAPMNVRRGL 395

  Fly  1492 GGSTRSQDLVQIKLAIQAQTKRANAQETLMYKATQTQDAAGGAGHVQTADRGVQANHESREGGSK 1556
            .|:|...|::.:.....     .:.:.|.|.:.....|.....|.:|||          |||...
  Rat   396 AGATTLGDMIYVSGGFD-----GSRRHTSMERYDPNIDQWSMLGDMQTA----------REGAGL 445

  Fly  1557 LLKS---------------NS-RAYVPHRAS----SQVATERNS-----LNLH 1584
            ::.|               || ..|.||...    :.:||:|:.     ||.|
  Rat   446 VVASGIIYCLGGYDGLNILNSVEKYDPHTGHWTNVTPMATKRSGAGVALLNDH 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13917	NP_001189017.1	BTB	1117..>1185	CDD:279045	15/77 (19%)
		BTB	1128..>1191	CDD:197585	16/72 (22%)
		BACK	1238..>1281	CDD:197943	9/42 (21%)
Klhl12	XP_038946329.1	BTB_POZ_KLHL12_C3IP1_DKIR	29..159	CDD:349551	34/159 (21%)
		PHA03098	63..574	CDD:222983	98/514 (19%)
		BACK_KLHL12	154..289	CDD:350527	30/192 (16%)
		KELCH repeat	298..339	CDD:276965	5/40 (13%)
		KELCH repeat	343..389	CDD:276965	10/49 (20%)
		KELCH repeat	393..436	CDD:276965	7/47 (15%)
		KELCH repeat	440..483	CDD:276965	9/42 (21%)
		KELCH repeat	487..531	CDD:276965	4/12 (33%)
		KELCH repeat	534..579	CDD:276965

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910