DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG13917 and Klhl21

DIOPT Version :9

Sequence 1:NP_001189017.1 Gene:CG13917 / 38186 FlyBaseID:FBgn0035237 Length:2019 Species:Drosophila melanogaster
Sequence 2:NP_001028524.1 Gene:Klhl21 / 242785 MGIID:1919288 Length:597 Species:Mus musculus


Alignment Length:425 Identity:88/425 - (20%)
Similarity:131/425 - (30%) Gaps:162/425 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly  1135 GRRIRAHKCILRSRCQYFAAMLAGHGSQS---VVSLQGYSYAAVHFALCHIYSGASHPPDGISLM 1196
            ||...||:.:|.:...||.||.||...:|   .|.|.|.....:...|...|:|.. ...|.:..
Mouse    44 GRDFPAHRAVLAAASPYFRAMFAGQLRESRAERVRLHGVPPDMLQLLLDFSYTGRV-AVSGDNAE 107

  Fly  1197 ELAALADLLGLEGLKEVTAHALK-----------TNYCHNFHKPCSGCSDGI------------- 1237
            .|...||||....:||.....|:           .::...|  .|||.:...             
Mouse   108 PLLRAADLLQFPAVKEACGAFLQQQLDLANCLDMQDFAEAF--SCSGLASAAQRFILRHVGELGA 170

  Fly  1238 --LQVLPVA--LNHALDD---------LYRKCLRWT-------CRHYLKVWP----------TRQ 1272
              |:.||:|  |.:..||         .|:..|||.       ..|    ||          .|:
Mouse   171 EQLERLPLARLLRYLRDDGLCVPKEEAAYQLALRWVRADPPRRAPH----WPQLLEAVRLPFVRR 231

  Fly  1273 F------------AQLPP--DILGRCRQ-QIVAYMTSD------------TVLDTVL-------- 1302
            |            |:.||  .:|...|. |...|...|            |.|..:|        
Mouse   232 FYLLAHVEAEPLVARCPPCLRLLREARDFQAARYDRHDRGPCPRMRPRPSTGLAEILVLVGGCDQ 296

  Fly  1303 DCDHLLAQLSAY-----RWGHVCEQLVREILEAAYAYVGDHFASLIASDSFLSLGHDRSRHIPRL 1362
            |||.|:. :..|     :|.::.|  ..:.|...|:.|.      :.:|.:::.|.|.|      
Mouse   297 DCDELVT-VDCYNPQTGQWRYLAE--FPDHLGGGYSIVA------LGNDIYVTGGSDGS------ 346

  Fly  1363 ETLLLHTAAELTPEQACRSYQRVTRLNT----------VLQAKVIHMPASLGQSELARELQGL-- 1415
                             |.|..|.|.|:          :|:|:..|.         :..|.||  
Mouse   347 -----------------RLYDCVWRYNSSVNEWTEVAPMLKAREYHS---------SSVLDGLLY 385

  Fly  1416 -----QEEQLDWQPEYIRLVGALVYAVEQCLIRQC 1445
                 ..|:.|...:....:..:.|.::.|....|
Mouse   386 VVAADSTERYDHATDSWEALQPMTYPMDNCSTTAC 420

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG13917NP_001189017.1 BTB 1117..>1185 CDD:279045 17/52 (33%)
BTB 1128..>1191 CDD:197585 18/58 (31%)
BACK 1238..>1281 CDD:197943 19/84 (23%)
Klhl21NP_001028524.1 BTB 49..547 CDD:333434 86/420 (20%)
Kelch 1 287..335 11/56 (20%)
KELCH repeat 326..368 CDD:276965 11/70 (16%)
Kelch 2 336..382 13/77 (17%)
KELCH repeat 372..409 CDD:276965 6/45 (13%)
Kelch 3 384..422 5/37 (14%)
KELCH repeat 412..451 CDD:276965 2/9 (22%)
Kelch 4 423..470
Kelch 5 472..512
KELCH repeat 502..548 CDD:276965
Kelch 6 513..560
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 570..597
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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