DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13917 and abtb1

DIOPT Version :9

Sequence 1:	NP_001189017.1	Gene:	CG13917 / 38186	FlyBaseID:	FBgn0035237	Length:	2019	Species:	Drosophila melanogaster
Sequence 2:	NP_001096209.1	Gene:	abtb1 / 100124760	XenbaseID:	XB-GENE-976579	Length:	477	Species:	Xenopus tropicalis

Alignment Length:	436	Identity:	95/436 - (21%)
Similarity:	163/436 - (37%)	Gaps:	118/436 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly  1107 CRQPRRLGEDLLKMFLQEIA-TDMLVEVHGRRIRAHKCILRSRCQYFAAMLAGH-GSQSVVSLQG 1169
            |.| |...:|.|:..|::.: :|.:..|||...:||:|:|.:|..|||.|.... ..::|:.|:.
Frog    95 CMQ-RDYYDDFLQRLLEQGSYSDTVFIVHGESFQAHRCVLSARSPYFAEMFENKWKGKNVIGLKH 158

  Fly  1170 --YSYAAVHFALCHIYSG-----ASHPPDGISLMELAALADLLGLEGLKEVTAHALKTNYCHNFH 1227
              .:.||....|.::|:|     ..|..|...|.:...|.||  ::.|:|      |....:.|.
Frog   159 PLVNPAAFGSILQYLYTGHMDIDVEHVEDCKRLAKQCRLQDL--IDDLEE------KCKKVYEFV 215

  Fly  1228 KPCSGCSDGILQVLPVALNHALDDLYRKCLRWTCR--HYLKVWPTRQFAQLP----------PDI 1280
            ....|....:|.|.|....|..:||   .:...|.  ..|:|    .|.:||          ||:
Frog   216 SSKPGTCVKVLSVEPSGNGHLQEDL---AILADCALPAELRV----GFGELPFDSTDNFSSYPDV 273

  Fly  1281 LGRCRQQIVAYMTSDTVLDTVLDC---DHLLAQLSAYRWGHVCEQ------------LVREILEA 1330
               | .||..|   :.:......|   |:..|.|.    .|.||.            .:..|.|.
Frog   274 ---C-FQIAGY---NFLCHKSFFCGRSDYFKALLE----DHFCESHELQALPSIPVITLHNITEE 327

  Fly  1331 A------YAYVGD-------HFASLIASDSFLSLGHDRSRHIPRLETLLLHTAAELTPE------ 1376
            .      |.|..|       .:..|..:|.:|         :|.|:.|...|.|::..|
Frog   328 TFMRVLYYIYSDDTELSPDNAYEVLCVADMYL---------LPGLKRLCGKTLAQMLDEDSIIGI 383

  Fly  1377 -QACRSYQRVTRLN---TVLQAKVIHMPASLGQSE-----LARELQGLQEEQLDWQPEYIRLVGA 1432
             :..:.:| :|||.   |...|::|.   .|..||     :..:.:.::|.|   :.:.|.|:..
Frog   384 WKTAKLFQ-LTRLEDQCTEYMARIIE---KLVDSEEFAAAVREDAEAVEERQ---ETDSIPLIDD 441

  Fly  1433 LVYAVEQCLIRQCSRAMRVTAWQRMDLELRKKIQTLARLTEPLDMK 1478
            :.:.:          ...|..:..:: |..::::.|..|...|:::
Frog   442 IRFHI----------TSNVQTYSAIE-EANQRLEALENLLASLELE 476

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13917	NP_001189017.1	BTB	1117..>1185	CDD:279045	21/71 (30%)
		BTB	1128..>1191	CDD:197585	21/70 (30%)
		BACK	1238..>1281	CDD:197943	14/54 (26%)
abtb1	NP_001096209.1	ANK	6..94	CDD:238125
		ANK repeat	35..66	CDD:293786
		BTB	105..210	CDD:306997	31/112 (28%)
		BTB	272..375	CDD:197585	25/122 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910