Protein Alignment CG12004 and TMEM184C

DIOPT Version :9

• Sequence 1: NP_001097474.1
• Gene: CG12004 / 38185
• FlyBaseID: FBgn0035236
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_060711.2
• Gene: TMEM184C / 55751
• HGNCID: 25587
• Length: 438
• Species: Homo sapiens
• Alignment Length: 442
• Identity: 137/442 - (30%)
• Similarity: 215/442 - (48%)
• Gaps: 74/442 - (16%)

  Fly    53 LHVGDGIFLQTKTAQVLAGVCVWAALFITCQQIYQHLRWYTNPQEQRWIVRILFIVPIYATYSWI 117
            |.||    :.|| |..:||:.:...:.|:...|.|||..||.|:.|:.|:|||::||||:..|||
Human    40 LEVG----IHTK-AWFIAGIFLLLTIPISLWVILQHLVHYTQPELQKPIIRILWMVPIYSLDSWI 99

  Fly   118 SLLFFNSDNVYIYFFTVRDCYEAFVIYNFLSLCYEYLGGE-GNIMSEIRGK-------PIKTSCL 174
            :|.:   ..:.||..|.|:||||:|||||:.....||... .|::..:..|       |:   |
Human   100 ALKY---PGIAIYVDTCRECYEAYVIYNFMGFLTNYLTNRYPNLVLILEAKDQQKHFPPL---C- 157

  Fly   175 YGTCCLKGKTYTIG--FLRFCKQATLQFCLVKPLVAFIIIFLQAFGHYHDGDWSADGGYIYITII 237
               ||   ..:.:|  .|..||...||:.:|:|....:.:..:..|.|.:|::|....:.|:.||
Human   158 ---CC---PPWAMGEVLLFRCKLGVLQYTVVRPFTTIVALICELLGIYDEGNFSFSNAWTYLVII 216

  Fly   238 YNISVSLALYGLYLFYFATRDLLTPFEPVLKFCTIKSVIFLSFWQGVGLAILEKANVISPIVDSA 302
            .|:|...|:|.|.|||...::.|:|.:||.||..:|.|:|:||||.|.:|:|.|..|||. ..:.
Human   217 NNMSQLFAMYCLLLFYKVLKEELSPIQPVGKFLCVKLVVFVSFWQAVVIALLVKVGVISE-KHTW 280

  Fly   303 GTVTVEPGTVSAGYQNFFICIEMLFAAIALRYAFPYQVYAR-----SCISDGHGRSVTMQSISSS 362
            ...|||  .|:.|.|:|.|||||..||||..|.|.|:.|.:     ||...    .:.|..:|
Human   281 EWQTVE--AVATGLQDFIICIEMFLAAIAHHYTFSYKPYVQEAEEGSCFDS----FLAMWDVS-- 337

  Fly   363 LKETMNPKDIMTDAIHNF------HPQYQQYTQYSSGGKNSRGIRVSSYDPDDPSSGAAAGGMQA 421
                 :.:|.:::.:.:.      ||:.:.:.:.....:::..:..||.|         |..:.:
Human   338 -----DIRDDISEQVRHVGRTVRGHPRKKLFPEDQDQNEHTSLLSSSSQD---------AISIAS 388

  Fly   422 SQPTS--GGYDAVA------TGPGSGGNGGSNCMASKTLGNQRKFQPGGQRV 465
            |.|.|  |.|....      |.|.:...  |:.:.|.|:|.::  :|..:.|
Human   389 SMPPSPMGHYQGFGHTVTPQTTPTTAKI--SDEILSDTIGEKK--EPSDKSV 436

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12004	NP_001097474.1	Solute_trans_a	66..339	CDD:397604	106/282 (38%)
TMEM184C	NP_060711.2	Solute_trans_a	50..316	CDD:308940	106/281 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	355..438		19/95 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2641
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D411703at33208
OrthoFinder	1	1.000	-	-		FOG0000529
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100407
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1529
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.750