Protein Alignment Tmep and tmem184c

DIOPT Version :10

• Sequence 1: NP_001097474.1
• Gene: Tmep / 38185
• FlyBaseID: FBgn0035236
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_001016532.1
• Gene: tmem184c / 549286
• XenbaseID: XB-GENE-1016397
• Length: 443
• Species: Xenopus tropicalis
• Alignment Length: 307
• Identity: 113/307 - (36%)
• Similarity: 164/307 - (53%)
• Gaps: 36/307 - (11%)

  Fly    53 LHVGDGIFLQTKTAQVLAGVCVWAALFITCQQIYQHLRWYTNPQEQRWIVRILFIVPIYATYSWI 117
            :.||    :.|| |..:||:.|...:.|:...|.|||..||.|:.|:.|:|||::||||:..|||
 Frog    38 MEVG----VHTK-AWFIAGIFVLMTIPISLWGILQHLVHYTQPELQKPIIRILWMVPIYSVDSWI 97

  Fly   118 SLLFFNSDNVYIYFFTVRDCYEAFVIYNFLSLCYEYLGGE-GNIMSEIRGKPIKTSCLYGTCCLK 181
            :|.:   .::.||..|.|:||||:|||||:.....||... .|:...:..|..:.......||
 Frog    98 ALKY---PDIAIYVDTCRECYEAYVIYNFMIFLLNYLTNRCPNLALVLEAKDQQRHLPPLCCC-- 157

  Fly   182 GKTYTIG--FLRFCKQATLQFCLVKPLVAFIIIFLQAFGHYHDGDWSADGGYIYITIIYNISVSL 244
             ..:.:|  .|..||...||:.:|:|:...|.:..|..|.|.:||:|....:.|:.||.|:|...
 Frog   158 -PPWAMGDVLLFRCKLGVLQYTVVRPVTTVIALICQLTGVYGEGDFSVKNAWTYLVIINNVSQVF 221

  Fly   245 ALYGLYLFYFATRDLLTPFEPVLKFCTIKSVIFLSFWQGVGLAILEKANVIS------PIVDSAG 303
            |:|.|.|||...::.|.|.:||.||..:|.|:|:||||.|.:|||.||.|||      .:.|
 Frog   222 AMYCLVLFYKVLKEELNPIQPVGKFLCVKMVVFVSFWQAVFIAILVKAGVISNTWEWKKVQD--- 283

  Fly   304 TVTVEPGTVSAGYQNFFICIEMLFAAIALRYAFPYQVYAR-----SC 345
                    |:.|.|:|.||:||..||:|..::|.|:.|.:     ||
 Frog   284 --------VATGLQDFIICVEMFLAAVAHHFSFTYKPYVQEAEEGSC 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tmep	NP_001097474.1	Solute_trans_a	66..341	CDD:460991	106/283 (37%)
tmem184c	NP_001016532.1	Solute_trans_a	46..313	CDD:460991	106/283 (37%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	369..422