DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12004 and Tmem184a

DIOPT Version :9

Sequence 1:	NP_001097474.1	Gene:	CG12004 / 38185	FlyBaseID:	FBgn0035236	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	XP_038945317.1	Gene:	Tmem184a / 304325	RGDID:	1306702	Length:	460	Species:	Rattus norvegicus

Alignment Length:	474	Identity:	242/474 - (51%)
Similarity:	304/474 - (64%)	Gaps:	69/474 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 AGSLEATGKPNYVVQVKNTPMSTPLDPLLHVG-------DG------IFLQTKTAQVLAGVCVWA 76
            :|.|:..|.| .|......|...|..|::..|       :|      :||.:..|:.::||.||.
  Rat    40 SGFLKTAGAP-LVSATWLPPSPPPAMPMVAAGPQMERVDNGSQGAPQLFLTSALARGVSGVFVWT 103

  Fly    77 ALFITCQQIYQHLRWYTNPQEQRWIVRILFIVPIYATYSWISLLFFNSDNVYIYFFTVRDCYEAF 141
            ||.:|..|||.|||.||.|:|||:::|:||||||||..||:|||.......|:||.:||||||||
  Rat   104 ALLLTGHQIYSHLRSYTVPREQRFVIRLLFIVPIYAFDSWLSLLLLGGHPYYVYFDSVRDCYEAF 168

  Fly   142 VIYNFLSLCYEYLGGEGNIMSEIRGKPIKTSCLYGTCCLKGKTYTIGFLRFCKQATLQFCLVKPL 206
            |||:||:||::|||||..||:|||||||::||.||||||:|.:|:|.|||||||||||||:|||:
  Rat   169 VIYSFLTLCFQYLGGESAIMAEIRGKPIRSSCFYGTCCLRGMSYSITFLRFCKQATLQFCIVKPV 233

  Fly   207 VAFIIIFLQAFGHYHDGDWSADGGYIYITIIYNISVSLALYGLYLFYFATRDLLTPFEPVLKFCT 271
            :|.|.|.||||..|||||::...||:|:|::||.|||||||.|:||||||||||.||||||||.|
  Rat   234 MALITIILQAFDKYHDGDFNIHSGYLYVTLVYNASVSLALYALFLFYFATRDLLRPFEPVLKFLT 298

  Fly   272 IKSVIFLSFWQGVGLAILEKANVISPIVDSAGTVTVEPGTVSAGYQNFFICIEMLFAAIALRYAF 336
            ||::||||||||:.|||||:..|| |.|.:.....|..||::||||||.||||||||::||||||
  Rat   299 IKAIIFLSFWQGMLLAILERCGVI-PEVQAVDGTRVGAGTLAAGYQNFLICIEMLFASLALRYAF 362

  Fly   337 PYQVYARSCISDGHGRSVTMQSISSSLKETMNPKDIMTDAIHNFHPQYQQYTQYSSGGKNSRGIR 401
            |.|||:..  .:.......||||||.||||::|:||:.||||||.|.||||||.|:
  Rat   363 PSQVYSEK--KNSPAPPAPMQSISSGLKETISPQDIVQDAIHNFSPAYQQYTQQST--------- 416

  Fly   402 VSSYDPDDPSSGAAAGGMQASQPTSGGYDAVAT--GPGSGGNGGSNCMASKTLGNQRKFQPGGQR 464
                             .:|..|..||:.:.:|  ||.||..||..
  Rat   417 -----------------HEAPGPGQGGHPSPSTHPGPASGSGGGKK------------------- 445

  Fly   465 VATISQNYNEKTMLLSSDD 483
                |:|. ||.||:.|:|
  Rat   446 ----SRNI-EKRMLIPSED 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12004	NP_001097474.1	Solute_trans_a	66..339	CDD:397604	181/272 (67%)
Tmem184a	XP_038945317.1	Solute_trans_a	96..365	CDD:397604	180/269 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	400	1.000	Domainoid score	I715
eggNOG	1	0.900	-	-		E1_KOG2641
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	465	1.000	Inparanoid score	I1478
OMA	1	1.010	-	-		QHG55062
OrthoDB	1	1.010	-	-		D411703at33208
OrthoFinder	1	1.000	-	-		FOG0000529
OrthoInspector	1	1.000	-	-		otm45765
orthoMCL	1	0.900	-	-		OOG6_100407
Panther	1	1.100	-	-	LDO	PTHR23423
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1310
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.840