Protein Alignment Tmep and Tmem184c

DIOPT Version :10

• Sequence 1: NP_001097474.1
• Gene: Tmep / 38185
• FlyBaseID: FBgn0035236
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: XP_006255484.1
• Gene: Tmem184c / 291946
• RGDID: 727852
• Length: 545
• Species: Rattus norvegicus
• Alignment Length: 419
• Identity: 133/419 - (31%)
• Similarity: 189/419 - (45%)
• Gaps: 89/419 - (21%)

  Fly    51 PLLHVGDGIFLQTKTAQVLAGVCVW----------------AALF------ITCQQIYQHLRWYT 93
            |||     |.|......|...||:|                |.:|      ::...|.|||..||
  Rat    58 PLL-----ILLYALAILVTVPVCIWEFQKLKVGIHTKVWFIAGIFLLLTIPVSMCGILQHLVHYT 117

  Fly    94 NPQEQRWIVRILFIVPIYATYSWISLLFFNSDNVYIYFFTVRDCYEAFVIYNFLSLCYEYLGGE- 157
            .|:.|:.|:|||::||||:..||::|.:   ..:.||..|.|:||||:|||||:.....||...
  Rat   118 QPELQKPIIRILWMVPIYSLDSWVALKY---PKIAIYVDTWRECYEAYVIYNFMIFLTNYLTIRF 179

  Fly   158 GNIMSEIRGKPIKTSCLYGTCCLKGKTYTIG-FLRF-CKQATLQFCLVKPLVAFIIIFLQAFGHY 220
            .|:|..:..|. :.:.|...||.  ..:.:| .|.| ||...||:.:|:|:.....:..:..|.|
  Rat   180 PNLMLHLEAKD-QQNHLPPLCCC--PPWAMGEMLLFRCKLGVLQYTVVRPITTVTSLVCEILGVY 241

  Fly   221 HDGDWSADGGYIYITIIYNISVSLALYGLYLFYFATRDLLTPFEPVLKFCTIKSVIFLSFWQGVG 285
            .:|::|....:.|:.|:.|:|...|:|.|.|||...::.|:|.:||.||..:|.|:|:||||.|.
  Rat   242 DEGNFSFSNAWTYLVILNNLSQLFAMYCLLLFYKVLKEELSPIQPVGKFLCVKLVVFVSFWQAVL 306

  Fly   286 LAILEKANVISPIVDSAGTVTVEPGT--------VSAGYQNFFICIEMLFAAIALRYAFPYQVYA 342
            :|:|.|..|||           |..|        |:.|.|:|.|||||.|||||..|.|.|:.|.
  Rat   307 IALLVKVGVIS-----------EKRTWEWQSAEAVATGLQDFIICIEMFFAAIAHHYTFSYKPYV 360

  Fly   343 RS-----CISDGHGRSVTMQSISSSLKETMNPKDIMTDAIHNFHPQYQQYTQYSSGGKNSRGIRV 402
            ..     |...    .:.|..:|          ||..|...          |....|:..||...
  Rat   361 HEAEEGPCFDS----FLAMWDVS----------DIREDISE----------QVRRVGRTMRGYPK 401

  Fly   403 SSYDPDDP-----SSGAAAGGMQASQPTS 426
            ....|.||     ||..:|....:|:|:|
  Rat   402 KKCFPGDPDHNEHSSLLSASSQDSSKPSS 430

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tmep	NP_001097474.1	Solute_trans_a	66..341	CDD:460991	108/307 (35%)
Tmem184c	XP_006255484.1	Solute_trans_a	90..359	CDD:460991	104/285 (36%)