Protein Alignment CG12004 and TMEM184B

DIOPT Version :9

• Sequence 1: NP_001097474.1
• Gene: CG12004 / 38185
• FlyBaseID: FBgn0035236
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: XP_016884243.1
• Gene: TMEM184B / 25829
• HGNCID: 1310
• Length: 452
• Species: Homo sapiens
• Alignment Length: 483
• Identity: 262/483 - (54%)
• Similarity: 307/483 - (63%)
• Gaps: 88/483 - (18%)

  Fly    15 ASSGNATATTAGSLEATGKPNYVVQVKNTPMSTPLDPLLHVGDGIFLQTKTAQVLAGVCVWAALF 79
            ||...|.|:.:.|:...|.|        |.|..|          :||.|..||.::|..||.||.
Human    46 ASPTTAAASPSVSVIPEGSP--------TAMEQP----------VFLMTTAAQAISGFFVWTALL 92

  Fly    80 ITCQQIYQHLRWYTNPQEQRWIVRILFIVPIYATYSWISLLFFNSDNVYIYFFTVRDCYEAFVIY 144
            |||.|||.|||.|:.|.|||:||||||||||||..||:|||||.:|..|:||.||||||||.|||
Human    93 ITCHQIYMHLRCYSCPNEQRYIVRILFIVPIYAFDSWLSLLFFTNDQYYVYFGTVRDCYEALVIY 157

  Fly   145 NFLSLCYEYLGGEGNIMSEIRGKPIKTSCLYGTCCLKGKTYTIGFLRFCKQATLQFCLVKPLVAF 209
            |||||||||||||.:||||||||||::||:||||||.||||:|||||||||||||||:||||:|.
Human   158 NFLSLCYEYLGGESSIMSEIRGKPIESSCMYGTCCLWGKTYSIGFLRFCKQATLQFCVVKPLMAV 222

  Fly   210 IIIFLQAFGHYHDGDWSADGGYIYITIIYNISVSLALYGLYLFYFATRDLLTPFEPVLKFCTIKS 274
            ..:.|||||.|.|||:....||:|:|||||||||||||.|:|||||||:||:|:.|||||..:||
Human   223 STVVLQAFGKYRDGDFDVTSGYLYVTIIYNISVSLALYALFLFYFATRELLSPYSPVLKFFMVKS 287

  Fly   275 VIFLSFWQGVGLAILEKANVISPIVDSAGTVTVEPGTVSAGYQNFFICIEMLFAAIALRYAFPYQ 339
            |||||||||:.||||||...| |.:.|| .|:|..|||:||||:|.||:||.|||:|||:||.|:
Human   288 VIFLSFWQGMLLAILEKCGAI-PKIHSA-RVSVGEGTVAAGYQDFIICVEMFFAALALRHAFTYK 350

  Fly   340 VYARSCISDGH------------GRSVTMQSISSSLKETMNPKDIMTDAIHNFHPQYQQYTQYSS 392
            |||...: |..            ||...|:||||||||||||.||:.||||||.|.||||||.
Human   351 VYADKRL-DAQASSPAPPAPCPAGRCAPMKSISSSLKETMNPHDIVQDAIHNFSPAYQQYTQQ-- 412

  Fly   393 GGKNSRGIRVSSYDPDDPSSGAAAGGMQASQPTSGGYDAVATGPGSGGNGGSNCMASKTLGNQRK 457
                      |:.:| .|:....|.|:..|...||..|
Human   413 ----------STLEP-GPTWRGGAHGLSRSHSLSGARD--------------------------- 439

  Fly   458 FQPGGQRVATISQNYNEKTMLLSSDDEY 485
                           ||||:|||||||:
Human   440 ---------------NEKTLLLSSDDEF 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12004	NP_001097474.1	Solute_trans_a	66..339	CDD:397604	194/272 (71%)
TMEM184B	XP_016884243.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	402	1.000	Domainoid score	I733
eggNOG	1	0.900	-	-		E1_KOG2641
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6396
Inparanoid	1	1.050	473	1.000	Inparanoid score	I1514
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55062
OrthoDB	1	1.010	-	-		D411703at33208
OrthoFinder	1	1.000	-	-		FOG0000529
OrthoInspector	1	1.000	-	-		otm41643
orthoMCL	1	0.900	-	-		OOG6_100407
Panther	1	1.100	-	-	O	PTHR23423
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1529
SonicParanoid	1	1.000	-	-		X1310
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.870