DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12004 and Tmem184c

DIOPT Version :9

Sequence 1:	NP_001097474.1	Gene:	CG12004 / 38185	FlyBaseID:	FBgn0035236	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_001351374.1	Gene:	Tmem184c / 234463	MGIID:	2384562	Length:	662	Species:	Mus musculus

Alignment Length:	442	Identity:	132/442 - (29%)
Similarity:	196/442 - (44%)	Gaps:	90/442 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 PLLHVGDGIFLQTKTAQVLAGVCVW----------------AALF------ITCQQIYQHLRWYT 93
            |||     :.....|..|...:|:|                |.:|      ::...|.|||..||
Mouse    56 PLL-----VLFYATTILVAVPICIWKFQKMKVGMHTKSWFIAGIFLLLTIPVSLWGILQHLVHYT 115

  Fly    94 NPQEQRWIVRILFIVPIYATYSWISLLFFNSDNVYIYFFTVRDCYEAFVIYNFLSLCYEYLGGE- 157
            .|:.|:.|:|||::||||:..||::|::   ..:.||..|.|:||||:|||||:.....||...
Mouse   116 QPELQKPIIRILWMVPIYSVDSWVALVY---PKIAIYVDTWRECYEAYVIYNFMIFLTNYLTIRF 177

  Fly   158 GNIMSEIRGKPIKTSCLYGTCCLKGKTYTIG-FLRF-CKQATLQFCLVKPLVAFIIIFLQAFGHY 220
            .|::..:..|..:...|...||   ..:.:| .|.| ||...||:.:|:|:.....:..:....|
Mouse   178 PNLILHLEAKDQQNHILPLCCC---PPWAMGEMLLFRCKLGVLQYTVVRPITTVTALVCEILDVY 239

  Fly   221 HDGDWSADGGYIYITIIYNISVSLALYGLYLFYFATRDLLTPFEPVLKFCTIKSVIFLSFWQGVG 285
            .:|::.....:.|:.|:.|:|...|:|.|.|||...::.|:|.:||.||..:|.|:|:||||.|.
Mouse   240 DEGNFGFSNAWTYLVILNNLSQLFAMYCLLLFYKVLKEELSPIQPVGKFLCVKLVVFVSFWQAVL 304

  Fly   286 LAILEKANVISPIVDSAGTVTVEPGT--------VSAGYQNFFICIEMLFAAIALRYAFPYQVYA 342
            :|:|.|..|||           |..|        |:.|.|:|.|||||.|||||..|.|.|:.|.
Mouse   305 IALLVKLGVIS-----------EKRTWEWQSAEAVATGLQDFIICIEMFFAAIAHHYTFSYKPYV 358

  Fly   343 R-----SCISDGHGRSVTMQSISSSLKETMNPKDIMTDAIHNFHPQYQQYTQYSSGGKNSRGIRV 402
            .     ||...    .:.|..:|          ||..|...          |....|:..||...
Mouse   359 HEAEEGSCFDS----FLAMWDVS----------DIRDDISE----------QVRRVGRTMRGYPK 399

  Fly   403 SSYDPDDPSSGAAAGGM-QASQPTSGGYDAVATGPGSGG--NGGSNCMASKT 451
            ....|.||.....:..: .:||..:.|...|   |..||  .|..:.::|::
Mouse   400 KKCFPGDPDHNEHSSLLSSSSQDLTSGSSKV---PSPGGLYQGFGHTISSQS 448

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12004	NP_001097474.1	Solute_trans_a	66..339	CDD:397604	103/305 (34%)
Tmem184c	NP_001351374.1	Solute_trans_a	90..356	CDD:308940	101/282 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2641
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D411703at33208
OrthoFinder	1	1.000	-	-		FOG0000529
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100407
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.720