DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7879 and rbm12b.1

DIOPT Version :9

Sequence 1:	NP_647626.1	Gene:	CG7879 / 38184	FlyBaseID:	FBgn0035235	Length:	985	Species:	Drosophila melanogaster
Sequence 2:	NP_001039079.1	Gene:	rbm12b.1 / 733876	XenbaseID:	XB-GENE-22063327	Length:	418	Species:	Xenopus tropicalis

Alignment Length:	570	Identity:	93/570 - (16%)
Similarity:	157/570 - (27%)	Gaps:	309/570 - (54%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSVIIRLQNLPWTANARDIRNFFSGLSIPEGGVHIIGGEMGDAFIAFSTDEDARCAMLKDREKLM 65
            |..|:||:.|...|::.||..||.|.::.:  :.|:.||.|:|||.|.:|..||.|:.|....:.
Frog     1 METIVRLEGLHADADSTDIEEFFKGFNVSD--IQIVRGERGEAFIVFGSDNHAREAIKKTGSWIK 63

  Fly    66 EIQVRLLLSSRAEMQKVIETARKAASAQAPVSVPVPMPVVVPVTAAKVAGPAAPLPPIIGGLNTF 130
            ..::.|.||::.||....|..||              .||..:.|||
Frog    64 NKRILLTLSNKTEMLCAFEVYRK--------------KVVQTLEAAK------------------ 96

  Fly   131 LGQGQVKGVATGTVPSFLTYQQQAGITLSDVTGRRSRSRSSSSDDSDRERERDRQRERERGRKRR 195
                                                                      ::.|||:
Frog    97 ----------------------------------------------------------QQSRKRK 103

  Fly   196 SDRLDKSQERELKMVAGGGALPSPWAQPPQNQLPAVGLGLNMGLNLNLPQIPSLQSYTTSTTTTN 260
            .|
Frog   104 VD--------------------------------------------------------------- 105

  Fly   261 VTNNYNLEPSATSVQLLTALQQVSSGSAAPAQPSKSESEPIAFASVNPYAQMYPQLFQQQQMLLQ 325
                                                                         |||.
Frog   106 -------------------------------------------------------------MLLA 109

  Fly   326 QQQTQAKVSPTMGGSPGGGSTPQVVADTCYIRMSGMCQNTSYSDIRKYFQGMYIPHNGIKIMMV- 389
            |              ||          :.|:.:||:.|.|..:.|..:|:.:.:.    :|:..
Frog   110 Q--------------PG----------SLYVYLSGISQETKEAGIIDFFKSLAVE----QIIFCK 146

  Fly   390 --NGSRTGVAYVEFSRVSSAQKAVQRNNTMFRDRLIQIVPVGDDEFEMAE---ERAS--RQGQDG 447
              :||:||..:|:|:.|..|.:|::.|..:...:.:.::...::::..|.   |:.|  |:|
Frog   147 GRDGSKTGNGFVKFTNVVHANEALKFNKCLLDKQCLSVISASEEQWVNAGGTLEKTSKIREG--- 208

  Fly   448 SRSHGNHNGGDRGERGGGAPVPVPRPVTNV----------LYIEDLPQTTTEQDI--------MK 494
                                      .|||          :|:.:||....:.||        ::
Frog   209 --------------------------FTNVIASMHQQQFYIYLLNLPPKVKKSDIRDLLEDPQLE 247

  Fly   495 MFSASYTVVDILLSPSPKNRRESVAFVLFAREAEADSALQDTSKHYIGFR 544
            .|:.|      ||:.|.|..    .||:|..|::..:||....||...:|
Frog   248 DFNIS------LLTSSSKGE----GFVMFKNESQYQAALLAHGKHLHDYR 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7879	NP_647626.1	RRM1_RBM12_like	2..75	CDD:240954	25/72 (35%)
		RRM_hnRNPH_ESRPs_RBM12_like	355..425	CDD:240700	18/72 (25%)
		RRM	<364..551	CDD:223796	42/207 (20%)
		RRM_SF	478..549	CDD:240668	20/75 (27%)
		RRM_SF	702..773	CDD:240668
		RRM_hnRNPH_ESRPs_RBM12_like	910..982	CDD:240700
rbm12b.1	NP_001039079.1	RRM_SF	1..87	CDD:388407	32/101 (32%)
		RRM_SF	115..192	CDD:388407	18/80 (23%)
		RRM_SF	221..298	CDD:388407	20/77 (26%)
		RRM_SF	322..397	CDD:388407
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D132643at33208
OrthoFinder	1	1.000	-	-		FOG0001433
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13976
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020