Protein Alignment CG7879 and rbm12

DIOPT Version :10

• Sequence 1: NP_647626.1
• Gene: CG7879 / 38184
• FlyBaseID: FBgn0035235
• Length: 985
• Species: Drosophila melanogaster
• Sequence 2: NP_001003856.1
• Gene: rbm12 / 445379
• ZFINID: ZDB-GENE-081022-16
• Length: 876
• Species: Danio rerio
• Alignment Length: 1106
• Identity: 252/1106 - (22%)
• Similarity: 393/1106 - (35%)
• Gaps: 353/1106 - (31%)

  Fly     1 MSVIIRLQNLPWTANARDIRNFFSGLSIPEGGVHIIGGEMGDAFIAFSTDEDARCAMLKDREKLM 65
            |:|:||||.||..|...|||:|||||:||:|||||:|||.|:|||.|:||||||..|::....:.
Zfish     1 MAVVIRLQGLPIVAGTMDIRHFFSGLTIPDGGVHIVGGEHGEAFIVFATDEDARLGMMRTGGSIK 65

  Fly    66 EIQVRLLLSSRAEMQKVIETARKA-ASAQAPVSVPVPMPVVVPVTAAKVAGPAA-PLPPIIGGLN 128
            ..:|.|||||:.|||.:||.:|:. .:..|.|:                ||..: |.||:..|.:
Zfish    66 GSKVSLLLSSKTEMQNMIELSRRRFETGSADVA----------------AGNGSRPGPPVSTGGS 114

  Fly   129 TFLGQGQVKGVATGTVPSFLTYQQQAGITLSDVTGRRSRSRSSSSDDSDRERERDRQRERERGRK 193
               |:|.:...|.|...:..|....|..|...|:.:...:.|:::
Zfish   115 ---GRGNLPTTAQGFSNTTSTTSTTAVSTHEPVSNKTVPTFSTTT-------------------- 156

  Fly   194 RRSDRLDKSQERELKMVAGGGALPSPWAQPPQNQL--PAVGLGLNM-----GLNLNLPQIPSLQS 251
                               .|::|     |..|..  |::.||..|     .||...|.||.|.:
Zfish   157 -------------------MGSMP-----PNFNNFTSPSLSLGSTMTTAMSSLNSVPPPIPPLPA 197

  Fly   252 YTT-----------------STTTTNVTNNYNLEPSATSVQLLTALQQVSSGSAAPAQP---SKS 296
            ..|                 ...|.|...:....|....:..|:||...:.|...|..|   ..:
Zfish   198 MPTLPPMPPIPVPPPVSALPPVPTVNPLTSVPQVPPIAHMPHLSALPPFNPGIPPPVGPVPGGLA 262

  Fly   297 ESEPIAFASVNPYAQMYPQLFQQQQMLLQQQQTQAKVSPTMGGSPGGGSTPQVVADTCYIRMSGM 361
            .|.|::..:.||  .....|.....:.||.....|..:|                |..|:.:.|:
Zfish   263 ASGPLSLGNSNP--MFLNPLNPLNPLNLQPHMKSAITNP----------------DDFYVHLHGL 309

  Fly   362 CQNTSYSDIRKYFQGMYIPHNGIKIMMVN-GSRTGVAYVEFSRVSSAQKAVQRNNTMFRDRLIQI 425
            ..:....:||.:|.|:.|  ..|:::..| |..:|.|.|:|.....:.:|::||..|...|.|::
Zfish   310 PFSVLEHEIRDFFHGLGI--ESIRLLKDNLGRNSGRALVKFYSPHESFEALKRNAGMIGQRYIEV 372

  Fly   426 VPVGDDEFEMAEERASRQGQDGSRSHGNHNGGDRGERGGGAPVP---------VPRPVTNVLYIE 481
            .|        |.||..|:....|::.|:........|...:|.|         .|..:...:|::
Zfish   373 SP--------ATERQWRESVGHSKAGGDSEHNRHRRRSANSPTPSSGERARSRSPHKLDYCVYLK 429

  Fly   482 DLPQTTTEQDIMKMFSASYTVVD-ILLSPSPKNRRESVAFVLFAREAEADSALQDTSKHYIGFRQ 545
            .||.....:.|.:.|.....|.| |.::..|..|.....||.|..|.:..:|| .....|:|.|.
Zfish   430 GLPYEAENKQIFEFFKNLDIVEDSIYIAYGPNGRATGEGFVEFRNEMDYKAAL-GCHMQYMGSRF 493

  Fly   546 LRVRSSSEEDMQNAKEKQRRANEQLLKEEADQREELLKDQQRRQKQQQQENENIQANRFAADPRR 610
            ::|...::::|.                                       |.|.|.|     :|
Zfish   494 IQVHPITKKNMY---------------------------------------EKIDAIR-----KR 514

  Fly   611 RQAEDQQQQQQMNMGPNFNSNMSPNMMAPFVNGGNMPFHMPPLQQNGVNNFPFNMNNNYNYNGNS 675
            .|.....|:.....|.:..|...                        :.|.|:|:.
Zfish   515 MQGSQGDQKSSSGGGKSAKSCAH------------------------ITNIPYNVT--------- 546

  Fly   676 NGNGPNYPNDNGGAGVIQRPRQEDVFVRVHNCEYATRANDLGELFSLEHLRIEHIEQLFNERNQS 740
                                 ::||.:.:          |..|||.      |.::.|.:.....
Zfish   547 ---------------------KKDVRLFL----------DGIELFE------ESLKVLVDSNGNG 574

  Fly   741 SGEFIVEF-SDPASCKLAIREFHNRRFRGRGLRVVAITPQEIADRMKKPFMDYLPGGNGPRKAET 804
            .|:.||:| ||..:.|  ....|.::..||...|..:|    .|:||:...:..|.....:|::.
Zfish   575 LGQAIVQFKSDEDALK--AERLHRQKLNGRDAFVHLVT----FDQMKEVERNPPPQAKRGQKSQQ 633

  Fly   805 N---------NANDGAGGNKASAQPSRR--RGPSRFDKPQEQPSQQQDRPLSLEREDNSSTSSNA 858
            |         :|:       |..||..:  :.|..|      |:...|. .|..| :...|..|.
Zfish   634 NAHAHLHSHVHAH-------AHVQPQAQVPQAPHAF------PTMTGDE-FSFLR-NAVGTLGNG 683

  Fly   859 PVKQHFNPFARPD---------PPLSSS----SLS---------------------PS------- 882
            |  ...|||..|.         ||||::    |||                     ||
Zfish   684 P--PFVNPFVAPGNGLTCPPPLPPLSTALADVSLSVPPPMVGGPLPGPILEHPGFRPSVNTAPPG 746

  Fly   883 -----------------------------NQGQVKPTSPVPVPTSIIPDKFNRPGCVVAMRNVPF 918
                                         ||||..|:..:..|:...|.. :|| .:|.::|:||
Zfish   747 FVGAPEPLRVMPPFDNGSSRKAVTQNRAGNQGQRPPSDNLRGPSPGGPGN-SRP-TIVKIQNMPF 809

  Fly   919 KAELKDIMRFFSDYKLSPDDIIRRFNDEGKPTGDTRVAFESPSEARSAFESRRKKQIFNRTVYLD 983
            ...:.:|:.||..|::.|..:..:|:|:|.|||:..|||:|..||.:|......:.|..|.|.:.
Zfish   810 TVTVDEIIDFFYGYQVLPGSVCLQFSDKGLPTGEAMVAFDSHDEAMAAVMDLNDRPIGARKVKIT 874

  Fly   984 I 984
            :
Zfish   875 L 875

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7879	NP_647626.1	RRM1_RBM12_like	2..75	CDD:409932	42/72 (58%)
		RRM_hnRNPH_ESRPs_RBM12_like	355..425	CDD:409699	20/70 (29%)
		RRM_SF	478..549	CDD:409669	19/71 (27%)
		RRM_SF	700..773	CDD:409669	17/73 (23%)
		RRM5_RBM12_like	909..983	CDD:409937	25/73 (34%)
rbm12	NP_001003856.1	RRM1_RBM12	1..92	CDD:241189	51/90 (57%)
		RRM_SF	301..375	CDD:473069	21/83 (25%)
		RRM3_RBM12	415..515	CDD:409934	26/144 (18%)
		RRM4_RBM12	535..622	CDD:410143	26/162 (16%)
		RRM5_RBM12	799..874	CDD:410145	26/75 (35%)